Olga Lidia Torres-Rocha,Julien Pinaud,Patrick Lacroix-Desmazes et al.
Olga Lidia Torres-Rocha et al.
Cellulose nanocrystals (CNC) offer unique mechanical and optical properties but face challenges that often prevent its commercial development, foremost its high hydrophilicity, which makes it incompatible with most polymers. Covalent polyme...
Multiple Levels of Organization in Amphiphilic Diblock Copolymers Based on Poly(γ-benzyl-l-glutamate) Produced by Aqueous ROPISA [0.03%]
基于聚（γ-苄基-L-谷氨酸）两亲性嵌段共聚物的多级组织结构ISA
Marianna Spyridakou,Ioannis Tzourtzouklis,Robert Graf et al.
Marianna Spyridakou et al.
A recent method for producing amphiphilic block copolymers and nano-objects based on the ring-opening polymerization-induced self-assembly (ROPISA) in aqueous buffer is explored with respect to the tunability toward nanostructures. ROPISA g...
Alexander J Bahnick,David Ruppert,Gabriella A Krisanic et al.
Alexander J Bahnick et al.
Mesh suture is an emerging technology for closing high-tension soft tissue wounds. However, bulky mesh surgical knots can irritate surrounding tissue and harbor bacteria, leading to an increased risk of infection and palpability. Thus, a de...
3D-Printed Protein-Based Bioplastics with Tunable Mechanical Properties Using Glycerol or Hyperbranched Poly(glycerol)s as Plasticizers [0.03%]
以甘油或超支化聚甘油作增塑剂的可用于调节机械性能的基于蛋白质的3D打印生物塑料
S Cem Millik,Naroa Sadaba,Shayna L Hilburg et al.
S Cem Millik et al.
Protein-based materials can be engineered to derive utility from the structures and functions of the incorporated proteins. Modern methods of protein engineering bring promise of unprecedented control over molecular and network design, whic...
Azo-Bridged Dextran: A Photoresponsive Sustainable Material with Photo-Tunable Mechanical Properties [0.03%]
偶氮桥连的右旋糖酐：一种光响应的可持续材料，具有光可调机械性能
Konstantin Knaipp,Rupert Kargl,Damjan Makuc et al.
Konstantin Knaipp et al.
We report on the synthesis, characterization, and properties of dextran polymers, which are covalently bridged/cross-linked by azobenzene moieties. The reversible photoactivity of the azo moiety is retained in the polymers, and the kinetics...
Shedding Light on Protein Aggregates by Bisindolyl-Based Fluorogenic Probes: Unveiling Mechanistic Pathways and Real-Time Tracking of Protein Aggregation [0.03%]
基于双吲哚基的荧光探针揭示蛋白质聚集物：揭露机制途径和实时追踪蛋白质聚集
Rikitha S Fernandes,Aditi Gangopadhyay,Nilanjan Dey
Rikitha S Fernandes
Herein, we synthesized a pair of oxidized bisindolyl derivatives with anthracene (probe 1) and pyrene (probe 2) fluorophores for selective protein aggregate detection, crucial in disorders like Alzheimer's disease. Probe 1 exhibited a signi...
Metformin-Loaded Tannic Acid Nanoparticles Attenuate Osteoarthritis by Promoting Chondrocyte Mitochondria Homeostasis Based on Mitocytosis [0.03%]
载葡萄糖酸乙酯鞣酸纳米粒通过线粒体发生促进软骨细胞线粒体稳态来缓解骨关节炎
Wacili Da,Xiangtian Deng,Quan Chen et al.
Wacili Da et al.
The oxidative stress microenvironment and mitochondrial dysfunction in chondrocytes are key mechanisms in the development of osteoarthritis (OA). Metformin (Met) has demonstrated multiple effects on mitochondria and is regarded as a potenti...
Synthesis and Characterization of Superhigh Moisturizing Carboxymethyl Tamarind Xyloglucan and Its Potential Application in Cosmetics [0.03%]
超保水羧甲基塔木胶xyloglucan的合成与表征及其在化妆品中的潜在应用研究
Ruxia Ning,Chi Feng,Fenglun Zhang et al.
Ruxia Ning et al.
Carboxymethyl tamarind xyloglucan (CMTXG) was synthesized by xyloglucan with sodium chloroacetate in 50% ethanol. The effects of carboxymethylation on the structure and properties of xyloglucan were studied, and its application potential in...
Iron-Doxorubicin Hyaluronan Nanogel as an Effective Targeted Chemotherapy with Modulated Cardiotoxicity [0.03%]
一种有效的针对心脏毒副作用调节的铁-阿霉素透明质酸纳米凝胶化疗药物
Hua Guo,Huimin Wang,Yiyi Zhang et al.
Hua Guo et al.
The complex of doxorubicin (Dox) and intracellular iron in cardiomyocytes generates reactive oxygen species (ROS), contributing to commonly observed cardiotoxicity. To enhance the anticancer potency and minimize the cardiotoxicity, here Dox...
Dual ROS/Glucose-Responsive Quercetin-Loaded Supramolecular Hydrogel for Diabetic Wound Healing [0.03%]
一种用于糖尿病伤口愈合的双功能ROS/葡萄糖响应型芦丁载药超分子水凝胶
Huan Liu,Ronger Ai,Bizhi Liu et al.
Huan Liu et al.
Diabetic wound healing remains a significant challenge due to complex pathological mechanisms, including prolonged inflammation, excessive reactive oxygen species (ROS) accumulation, angiogenesis dysfunction, and increased susceptibility to...