Reactivity Ratios of Biobased Dibutyl Itaconate with Conventional and Renewable (Meth)Acrylates: Influence of Depropagation [0.03%]
生物基衣康酸二丁酯与传统和可再生（甲）丙烯酸酯的反应性比值：脱丙氧化作用的影响
Jyoti Gupta,Radmila Tomovska,Shaghayegh Hamzehlou et al.
Jyoti Gupta et al.
The global push for sustainability has driven interest in renewable monomers such as dibutyl itaconate (DBI). Despite its potential for biobased high-performance polymers, DBI's copolymerization with (meth)acrylates is challenging due to lo...
Stoichiometric Antibody-Polymer-Drug Conjugate for Effective Low-Dose Treatment of Breast Cancer [0.03%]
定量抗体-聚合物-药物偶联物有效低剂量治疗乳腺癌
Victor Lehot,Ondřej Lidický,Julien Most et al.
Victor Lehot et al.
In the past two decades, antibody-drug conjugates (ADCs) have emerged as highly effective targeted therapeutics against cancers. One current path to improve ADCs is to increase the amount of cytotoxic payload delivered to cancer cells by co...
NMR Insights into Nanoscale Molecular Interactions between Nucleic Acids and Pristine Graphene in Aqueous Solution [0.03%]
水溶液中核酸与优质石墨烯纳米级分子相互作用的核磁共振研究
Budoor S Al Umairi,David J Clarke,Elena V Bichenkova
Budoor S Al Umairi
Delivery of oligonucleotide therapeutics to the sites of biological action is challenged by their large size and charge. Graphene can serve as a nanocarrier for their transport, but the nature of their molecular interactions with pristine g...
High-Strength Silk from Silkworms Fed Nitrogen-Doped Carbon Quantum Dots [0.03%]
氮掺杂碳量子点喂养家蚕制备高强度丝纤维
Mengyao Pan,Yuwei Jin,Zheyao Lu et al.
Mengyao Pan et al.
The excellent mechanical properties of fluorescent silk play a crucial role in biomedical applications, such as in tendon scaffolds and surgical sutures. However, producing fluorescent silk with high mechanical performance remains challengi...
RAFT-Polymerized Thermoresponsive Glycopolymer- Grafted-Nanoparticles: Modulation of Lectin Binding [0.03%]
RAFT接枝聚合得到的热响应糖基聚合物纳米颗粒及其与凝集素结合性质的研究
Somdatta Rudra,Saradamoni Mondal,Mithun Chakraborty et al.
Somdatta Rudra et al.
The ability of thermoresponsive glycopolymers to undergo solubility transitions at physiological temperatures can enable the modulation of carbohydrate-lectin interactions. This study examines the binding of thermoresponsive glycopolymer-gr...
Microstructure and Performance Evolution of Poly(l-Lactic Acid) during Physical Aging: Effect of Molecular Weight [0.03%]
分子量对聚乳酸物理老化过程中微结构和性能演化的影响研究
Zhi-Xuan Zhang,Chao-Qun Wu,Yi-Fan Zha et al.
Zhi-Xuan Zhang et al.
With the growing public awareness of environmental protection, poly(l-lactic acid) (PLLA) has started to establish a presence across various industries. However, the inevitable physical aging of PLLA products leads to substantial alteration...
Quaternized Nylon-6 Polymers via Ring-Opening Polymerization of Cyclic Lysine Derivatives: A Versatile Antibacterial Platform [0.03%]
通过环状赖氨酸衍生物的开环聚合制备季𬭸化尼龙-6聚合物：一种多功能抗菌平台
Yan Yan,Jinlong Chen,Qun-Liang Zhang et al.
Yan Yan et al.
Nylon-6, while commercially essential, has proven challenging to endow with persistent antibacterial properties due to the lack of efficient and facile synthetic approaches. Poly(ε-lysine) derivatives have attracted considerable research a...
Injectable Hydrogel with Phase-Programmed Release of Centella asiatica Nanocomposites for Infection Control and Scarless Wound Healing [0.03%]
具有分阶段释放积雪草复合纳米材料的可注射水凝胶在感染控制和无疤痕伤口愈合中的应用
Guangxu Wang,Qirui Gong,Yujie Zhao et al.
Guangxu Wang et al.
Infected wounds provoke persistent inflammation that hinders healing. Here, we developed a phase-adaptable, injectable hydrogel (PAC@TAP) that delivers sequential antibacterial, antioxidant, anti-inflammatory, and regenerative effects. Bioa...
Facile Exfoliation of Silk Nanofibrils Enabled by Hydrogen Bond Network Reconfiguration in Deep Eutectic Solvent/Water Systems [0.03%]
深 eutectic 溶剂/水体系中氢键网络重构诱导的蚕丝纳米纤维素片层易剥离制备方法研究
Wen-Qian Lian,Zi-Yang Fan,Sheng He et al.
Wen-Qian Lian et al.
Silk nanofibers (SNFs) with distinctive physicochemical properties are promising nanoscale building blocks of porous materials, yet high-yield exfoliation using green solvents remains challenging. Herein, hydrogen-bonding small molecules (w...
Unimer Exchange as a Tool for Programming Enzymatic Degradation through Micellar Dynamics [0.03%]
基于胶束动力学编程酶促降解的工具——连接臂型嵌段共聚物UniMer交换
Shahar Tevet,Michal Brodsky,Roey J Amir
Shahar Tevet
A key challenge in designing enzyme-responsive micellar nanocarriers lies in balancing their stability and enzymatic degradation. While it has been widely assumed that the micelle-unimer exchange governs enzyme accessibility to the hydropho...