Shedding Light on Protein Aggregates by Bisindolyl-Based Fluorogenic Probes: Unveiling Mechanistic Pathways and Real-Time Tracking of Protein Aggregation
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Herein, we synthesized a pair of oxidized bisindolyl derivatives with anthracene (probe 1) and pyrene (probe 2) fluorophores for selective protein aggregate detection, crucial in disorders like Alzheimer's disease. Probe 1 exhibited a significant "turn-on" ... ...
