Cu-Catalyzed Highly Selective Ritter-Type Reaction of Enaminonitriles with Cycloketoxime Esters: A Direct Route to Diverse α-Tertiary Amines [0.03%]
铜催化烯胺腈与环酮肟酯的高选择性里特尔反应：制备α-三级胺的新方法
Farrukh Sajjad,Jiaqi Zhao,Ling Zheng et al.
Farrukh Sajjad et al.
Significant progress has been made in recent years in Ritter-type reactions, particularly in developing diverse pathways for carbocation generation. However, most existing methods rely on stoichiometric oxidants or expensive reagents and ar...
Kinetic Resolution of Unprotected BINOLs via Lewis Base-Catalyzed O-Boc Protection [0.03%]
Lewis碱催化O-BOC保护反应实现BINOL未保护的对映选择性合成
Zhe Xu,Hongwei Zhou,Xingkuan Chen et al.
Zhe Xu et al.
A Lewis base-catalyzed kinetic resolution of 1,1'-bi-2,2'-naphthols (BINOLs) through atroposelective O-Boc protection is described. Using a commercially available biscinchona alkaloid catalyst, a broad range of unprotected BINOLs undergo se...
Cobalt-Catalyzed Regioselective Hydroxyazidation of 1,3-Dienes: Direct Access to β-Azido Alcohols [0.03%]
钴催化1,3-丁二烯区域选择性羟基叠氮化反应：β-叠氮醇的直接合成方法
Chi-Fan Zhu,Xiao-Jing Li,Jun-Ju Mai et al.
Chi-Fan Zhu et al.
A cobalt-catalyzed stereoselective 1,2-hydroxyazidation of 1,3-dienes has been developed, enabling efficient synthesis of β-azido alcohols, which retain a C═C bond for further derivatization. This protocol features a broad substrate scope...
Radical Borylation of Aryl Sulfones with N-Heterocyclic Carbene Borane: A Modular Approach to Aryl Boranes [0.03%]
N-杂环卡宾硼烷与芳基磺酮的极性交叉硼化反应：制备芳基硼化合物的新方法
Ryo Komatsu,Tsubasa Morioka,Akio Kamimura et al.
Ryo Komatsu et al.
Aryl boron compounds are central to modern synthetic chemistry, yet their preparation often relies on transition metal catalysis or reactive organometallic intermediates. Here, we report a transition-metal-free method for the synthesis of a...
Synthesis of (E)-Silyl-Acrylates via Ruthenium-Catalyzed Selective Dehydrogenative Si-H/C-H Silylation of Acrylates [0.03%]
钌催化烯酸酯选择性脱氢硅基化反应合成(E) acrylic silyl酯
Jiawan Ye,Ping Li,Ruxin Jin et al.
Jiawan Ye et al.
An efficient and selective ruthenium-catalyzed dehydrogenative Si-H/C-H silylation of acrylates is described. A broad range of (E)-silylated acrylates could be easily synthesized with good functional group tolerance in moderate to excellent...
Introduction of an Azoxy Moiety into Advanced Energetic Materials: A Case of Azoxyfuroxans [0.03%]
偶氮氧基取代高级能源材料研究的一个特例——偶氮氧基furloxans类化合物的研究进展
Yuri A Sidunets,Maksim Krykin,Alla N Pivkina et al.
Yuri A Sidunets et al.
A direct synthetic route to an assembly of new energetic materials composed of two 1,2,5-oxadiazole 2-oxide (furoxan) rings connected via an azoxy linker and coupled with a 4-nitramino-3,5-dinitrophenyl scaffold was realized. Due to an adva...
Asymmetric Allylation/Retro-Claisen Cascade Reaction of 1,3-Diketones and 1-Hydroxyallylphenols/Aniline Catalyzed by an Iridium Complex [0.03%]
由铱配合物催化1,3-二酮和1-羟基烯丙基苯酚/苯胺的不对称烯醇化/反向克莱森串联反应
Xiayu Zhang,Lixing Tan,Jiaxing Dong et al.
Xiayu Zhang et al.
An asymmetric allylation/retro-Claisen cascade reaction of 1-hydroxyallylphenols/aniline with 1,3-diarylketones has been developed, and a series of chiral γ,δ-unsaturated 1,3-diaryl ketones could be produced in good to excellent yields (u...
DBU-Mediated Diastereoselective C3-Quaternary Alkylation of Cyclic Dipeptides [0.03%]
脯氨酰胺β位的对映选择性官能团化反应
Ying Hu,Yu-Jia Rao,Yi Luo et al.
Ying Hu et al.
A mild and highly diastereoselective strategy for the direct C3-quaternary carbonation of cyclic dipeptides (CDPs) has been explored using DBU as a base. This approach enabled the efficient functionalization of the C3 position in CDPs that ...
Synthesis of Seven-Membered Nitriles by Formal Anionic Divinylcyclopropane Rearrangement [0.03%]
阴离子型二乙烯基环丙烷重排制备七元氮杂环化合物
Takashi Takeuchi,Yuki Yukutake,Junya Takino et al.
Takashi Takeuchi et al.
A method for the synthesis of 3-cyanocyclohepta-1,4-diene derivatives via divinylcyclopropane rearrangement was developed. The substrate was prepared via the intramolecular alkylation of a diene with a nitrile moiety. Although heating subst...
Copper-Catalyzed Three-Component Radical 1,2-Carboazidation of 1,3-Dienes [0.03%]
铜催化1,3-丁二烯的三组分自由基1,2-碳亚硝基化反应
Xiaoyan Shangguan,Yan Li,Qian Zhang
Xiaoyan Shangguan
Organic azides serve as versatile synthons in organic synthesis, owing to their unique reactivity. Although transition-metal-catalyzed radical azidative difunctionalization of alkenes has achieved considerable progress, the analogous transf...