Synthesis of Stereodefined Cyclopropylamine Derivatives from Cyclopropanols and Sulfinamides [0.03%]
由环丙醇和亚磺酰胺合成立体定义的环丙基胺衍生物
Katerina Scotchburn,Livi G Allen,Sophie A L Rousseaux
Katerina Scotchburn
The synthesis of cyclopropylamine derivatives has been achieved by the reaction of a cyclopropanol and a sulfinamide in the presence of base and a Zn(II) salt via a ring-opened homoenolate intermediate. Enantioenriched cyclopropylamines are...
Electron-Shuttle Catalysis by Diaryl Diselenides for Photochemical Anti-Markovnikov Hydroalkoxylation of Alkenes [0.03%]
diaryl diselenides催化的电子穿梭作用促进的烯烃光化学反马氏羟基官能化反应
Inho Jang,Hun Young Kim,Kyungsoo Oh
Inho Jang
The development of general anti-Markovnikov hydroalkoxylation methods remains challenging due to competing alkene oxidation and photocatalyst-alcohol compatibility issues. Herein, diaryl diselenides serve as efficient electron-shuttle catal...
Photocatalytic Synthesis of α-Fluoro-β-sulfonyl Carbonyl Compounds Using Nucleophilic Fluorine Sources [0.03%]
光催化合成α-氟-β-磺酰基羰基化合物的研究进展——从亲核性氟源出发
Jie Gong,Fang Wang,Shu-Hui Lei et al.
Jie Gong et al.
Herein, we report a photocatalytic synthesis of α-fluoro-β-sulfonyl carbonyl compounds using nucleophilic fluorine sources under photo redox-neutral conditions. The key to this transformation is the generation of α-carbonyl carbocations ...
Visible-Light-Induced Lactone-Fused Indoline Construction via Radical Dearomatization of Indoles with Alcohols [0.03%]
醇与吲哚自由基脱芳构化构建可见光诱导内酯环融合吲哚骨架反应研究
Jingshan Ai,Qihang Xu,Yaru Liu et al.
Jingshan Ai et al.
We report a visible-light-induced strategy for synthesizing lactone-fused indolines via the radical dearomatization of indoles with simple alcohols. This method combines hydrogen atom transfer (HAT) catalysis and Lewis acid activation opera...
A General Electrochemical C(sp3)-H Amination of Hydrocarbons Suitable for Inactive Alkanes, Alkenes and Alkynes [0.03%]
一种适用于惰性烷烃、烯烃和炔烃的官能团化通用电化学C(sp3)—H氨化反应
Zi-Ru Xu,Hui Gao,Pei-Long Wang et al.
Zi-Ru Xu et al.
The first example of the electrochemical C(sp3)-H amination of inactive hydrocarbons with sulfoximines was reported. We proposed the concept of an NH3-induced electrochemical reaction for the first time. Although the electrochemical C(sp3)-...
Casey J McCarthy,Marius Müller,Richard Ma et al.
Casey J McCarthy et al.
Radiocyanation is an attractive approach to introduce carbon-11 into radiopharmaceuticals, as nitriles and other acyl moieties. This report describes a Friedel-Crafts-type electrophilic radiocyanation of (hetero)aryltrimethylgermanes and tr...
Photochemical Zincke-like Reactions Enabled the Expeditious Synthesis of 2-Polyene Sulfonylpyridines [0.03%]
光化学型辛克反应实现多烯磺酰基吡啶的简洁合成
Min Shen,Nian-Hua Luo,Guo-Dong Zhu et al.
Min Shen et al.
A Ce-base-controlled and visible-light-induced approach enables the cleavage of NTf-pyridiniums into various 2-polyene sulfonylpyridines. This Zincke-like reaction involves the conversion of pyridines into electron-rich intermediates and su...
N-Annulated [5]Helicenes: Syntheses, (Anti)Aromaticity and Properties [0.03%]
N-拼合[5]手性螺烯：合成、（反）芳香性和性质
Hemonta Kumar Saha,Tarun,Vishvajeet Kumar et al.
Hemonta Kumar Saha et al.
N-Annulated [5]helicene (NH5) and its dibenzo-extended derivatives are synthesized by cycloisomerization and Scholl-type cyclodehydrogenation methods, respectively. Nitrogen-bridging of fjord-carbons 1 and 14 of [5]helicene endows saddle-li...
Biomimetic Iron-Catalyzed Oxidation of 3-Substituted Indoles to 2-Oxindoles [0.03%]
铁催化吲哚3位取代基的生物模拟氧化反应生成2-氧代吲哚化合物
Changyin Zhao,Yuzhen Dong,Hongbin Liu et al.
Changyin Zhao et al.
A biomimetic iron-catalyzed system has been developed for the selective oxidation of 3-substituted indoles to 3-monosubstituted 2-oxindoles using H2O2 as a green oxidant under mild conditions. This catalytic approach addresses the drawbacks...
User-Friendly Thioglycoside Preactivation via Instant Sulfenyl Chloride Generation [0.03%]
瞬时亚硫酰氯生成激活硫糖苷的用户友好性
Xingchun Sun,Xiao-Lin Zhang,Xin-Ru Qiao et al.
Xingchun Sun et al.
Thioglycoside preactivation enables one-pot oligosaccharide assembly but relies on unstable sulfenyl chloride activators. We report a user-friendly manifold that forms sulfenyl chlorides in seconds from common thiols and N-chlorosuccinimide...