Synthesis of Stereodefined Cyclopropylamine Derivatives from Cyclopropanols and Sulfinamides
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The synthesis of cyclopropylamine derivatives has been achieved by the reaction of a cyclopropanol and a sulfinamide in the presence of base and a Zn(II) salt via a ring-opened homoenolate intermediate. Enantioenriched cyclopropylamines are accessible by chira... ...