Bis-Pseudoindoxyls: A Compact Fluorophore with Red-Shifted Absorption and Fluorescence for Bioimaging Applications [0.03%]
用于生物成像应用的红移吸收和发射的紧凑荧光团双伪吲哚啉化合物
Tomohiro Yazawa,Masaya Nakajima,Akiko Takaya et al.
Tomohiro Yazawa et al.
A new class of single benzene-based fluorophores, bis-pseudoindoxyls, was developed. The core scaffold 14CO25NH is constructed via a visible-light-induced radical cyclization. Subsequent N-alkylation produced pronounced bathochromic shifts....
Electrochemical Dehydrocarboxylation of Alcohols Mediated by Cu0.5Ni0.5-LDH [0.03%]
由Cu0.5Ni0.5-LDH催化醇的电化学脱羧反应
Jiaxiu Liu,Xinyu Zhang,Weisi Guo et al.
Jiaxiu Liu et al.
Oxidation of primary alcohols to produce the corresponding carboxylic acids is a fundamental reaction in organic synthesis. In this article, we report a process for the oxidation of primary alcohols using chemically modified electrodes. Thi...
Stereocontrolled Synthesis of 8-Hydroxycurvularol, a Sesquiterpene with a Modified Trichothecene Skeleton [0.03%]
具有修饰的三帖骨架的倍半萜8-羟基kurvarol的立体选择性合成
Johanna M Masterson,Erik J Sorensen
Johanna M Masterson
The fungal-derived natural product curvularol (3) and its relative 8β-hydroxycurvularol (4) are a type of trichothecene with unique molecular skeletons and potential as anticancer agents. On the foundation of a known substituted cyclohexen...
Condition-Regulated Regiodivergent Synthesis of Biaryl Sulfones via Sulfonylation of Diaryl λ3-Bromanes and Chloranes [0.03%]
通过 diaryl λ3-bromane 和 chlorane 的磺化反应进行的条件依赖性的区域发散式联苯磺酸的合成
Jiahong Chen,Nan Wang,Yuanyuan Huang et al.
Jiahong Chen et al.
A regiodivergent sulfonylation of cyclic diaryl λ3-bromanes and λ3-chloranes has been developed, enabling the selective synthesis of biaryl sulfones. Under base-mediated conditions, meta-selective sulfonylation proceeds via aryne intermed...
Enantioselective Copper-Catalyzed N-H Insertion Reaction of Pyrazoles and α-Diazo Phosphates [0.03%]
手性铜催化吡唑与α-叠氮磷酸酯的N-H插入反应
Lewan Li,Mengxiang Luo,Yuqing Zhang et al.
Lewan Li et al.
Asymmetric N-H insertion reaction provides a streamlined process for accessing N-alkylated pyrazoles and their derivatives. However, the enantioselective N-H insertion reaction of aromatic heterocycles with diazo compounds represents a long...
Continuous-Flow Electrochemistry Enables 1,2-Arylheteroarylation of Alkenes [0.03%]
连续流动电解化学促进烯烃的1,2-芳基杂芳基化反应
Xiaohan Sun,Fantao Meng,Kun Xu et al.
Xiaohan Sun et al.
Despite its potential, the radical-mediated 1,2-arylheteroarylation of alkenes for constructing valuable 1,2-arylheteroaryl ethane motifs remains underdeveloped. We herein report an alternative continuous-flow electrochemical approach using...
Cu/Pd-Catalyzed Ligand-Controlled Regiodivergent Hydroarylation of Allenes Using Diisobutylaluminum Hydride [0.03%]
双异丁基铝 hydride 促进的醛烯烃配体控制区域选择性 allenoid 化合物加成反应
Seungho Kim,Kyeongmin Lee,Seeun Lim et al.
Seungho Kim et al.
We report a ligand-controlled, regiodivergent Cu/Pd-catalyzed hydroarylation of unactivated allenes. The reaction proceeds via Cu-catalyzed hydroalumination with DIBAL-H and subsequent additive-free Pd-catalyzed cross-coupling with aryl bro...
Stepwise Emission Tuning of Thermally Activated Delayed Fluorescence Emitters from the Orange to Near-Infrared Region by Rational Molecular Design [0.03%]
通过合理分子设计实现从橙色到近红外区域热激活延迟荧光发射体的逐步发射调谐
Shantaram Kothavale,Rajendra Kumar Konidena,Hyunjung Lee et al.
Shantaram Kothavale et al.
Herein, we unveiled a rational molecular design to develop rigid and strong acceptors through interlocking followed by cyano substitution to tune the emission wavelength of thermally activated delayed fluorescence emitters from the orange (...
Access to Conjugated Dienes and Cyclic Allenes via a Diazo-Dithiane Rearrangement Cascade [0.03%]
叠氮-二硫化合物重排串联反应合成共轭二烯和环三键化合物
Zhuzhu Zhang,Xiaomeng Gong,Yingze Jin et al.
Zhuzhu Zhang et al.
A transition-metal-free, base-promoted cascade between alkynyl-1,3-dithianes and α-diazodiesters has been developed. The reaction proceeds through an anion relay chemistry (ARC) featuring a selective 1,3-sulfur rearrangement, enabling dive...
Photoinduced Pd-Catalyzed Alkylvinylation of Alkenes via C-H Bond Elaboration [0.03%]
光促进的钯催化烯烃C-H键官能团化参与的烷基 vinyl 化反应
Wen-Ao Li,Xiao-Yun Ruan,Yi-Cong Liu et al.
Wen-Ao Li et al.
A photoinduced palladium-catalyzed alkylvinylation of electron-deficient alkenes has been developed through direct Csp3-H bond activation. This three-component cascade employs diverse Csp3-H donors (ethers, acetals, toluenes, cycloalkanes),...