Monte Carlo Resampling Validates Use of Bone Mineral Density Change as Surrogate to Replace Fracture in Future Randomized Trials of Osteoporosis Treatments: Results From SABER [0.03%]
基于SABER结果的蒙特卡洛重取样验证骨矿物质密度变化替代骨折作为未来随机试验疗效替代指标的有效性
Suzanne M Dufault,Austin R Thompson,Li-Yung Lui et al.
Suzanne M Dufault et al.
We have proposed 24-mo between-treatment difference (active-placebo) in mean percent change in total hip bone mineral density (%THBMD) be used to evaluate whether a drug will likely reduce fracture risk, such that a mean %THBMD change great...
Jump power testing as a screening tool to assess fracture risk: a giant leap or a hop in the right direction? [0.03%]
跳高测试作为评估骨折风险的筛选工具：越性的进步还是正确的方向上的跳跃？
Cassandra Smith,Namki Hong
Cassandra Smith
From frail bones that could not last long to strong bones that support a good and long life-the story of osteogenesis imperfecta [0.03%]
从脆弱的骨骼到坚强的生命——记骨生成不全症患者的故事
Peter Vestergaard
Peter Vestergaard
Serum albumin and the Prognostic Nutritional Index independently predict fracture risk in elderly women [0.03%]
血清白蛋白和营养预后指数可独立预测老年女性骨折风险
Raju Jaiswal,Berit A M Larsson,Maria Åberg et al.
Raju Jaiswal et al.
Serum albumin and the Prognostic Nutritional Index (PNI), based on albumin and lymphocytes, are markers of nutritional and inflammatory status and have been associated with frailty and adverse outcomes in older adults. However, their relati...
AnnexinA1-Dectin 1 axis is a key regulator of osteoclastogenesis underlying irradiation induced bone loss in male mice [0.03%]
annexin a1- dectin 1轴是辐射诱导的小鼠骨丢失中破骨细胞生成的关键调节因素
Gulnaz Guliyeva,Flora Nguemedjio Foko Takile,Verena Stallfort et al.
Gulnaz Guliyeva et al.
The molecular mechanisms linking immune cell signaling to osteoclastogenesis remain incompletely defined. Here, we identify an Annexin A1 (AnxA1)-Dectin-1 axis as a key driver of osteoclast differentiation. Dectin-1 (CLEC7A), a myeloid C-ty...
Journal of Bone and Mineral Research (JBMR) 40th anniversary celebration the third decade (part 1) [0.03%]
骨矿研究杂志(JBMR)四十周年庆典第三个十年（一）
Thomas L Clemens,John P Bilezikian
Thomas L Clemens
SIRT1 enhances alveolar bone repair by regulating glycolytic metabolism via the Wnt/β-catenin pathway [0.03%]
SIRT1通过Wnt/β-连环蛋白信号调节糖酵解代谢促进牙周骨缺损修复
Zerui Shan,Zhongyin Zhang,Yu Xia et al.
Zerui Shan et al.
The repair of alveolar bone is of vital importance for maintaining oral health and promoting recovery following injury or disease. Functioning as an NAD+-dependent protein deacetylase, SIRT1 modulates diverse physiological activities, with ...
Pre-operative MRI Bone Texture is Associated with Complications After Spine Fusion [0.03%]
术前MRI骨纹理与脊柱融合术后并发症的关系
Alison K Heilbronner,Shreya Addepalli,Olivia Blumberg et al.
Alison K Heilbronner et al.
Bone quality is a critical determinant of outcomes following spine fusion surgery. However, patients with skeletal deficits are often only identified intra-operatively when there are unexpected problems with hardware placement, or post-oper...
Chronic Non-bacterial Osteitis Presenting with Upper Limb Deep Vein Thrombosis: Diagnostic Clues and Therapeutic Considerations [0.03%]
慢性非细菌性骨髓炎伴发上肢深静脉血栓的诊断线索和治疗考虑因素
Nina Thomson,Jack Leese,James Bott et al.
Nina Thomson et al.