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AnnexinA1-Dectin 1 axis is a key regulator of osteoclastogenesis underlying irradiation induced bone loss in male mice

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The molecular mechanisms linking immune cell signaling to osteoclastogenesis remain incompletely defined. Here, we identify an Annexin A1 (AnxA1)-Dectin-1 axis as a key driver of osteoclast differentiation. Dectin-1 (CLEC7A), a myeloid C-type lectin receptor b... ...