Timothy M Sveeggen,Anna Kosmach,Ray Mitchell et al.
Timothy M Sveeggen et al.
The aorta varies in structural and biomechanical properties along its length, however, the influence of these properties on aortic pathology is poorly understood. By understanding vascular reactivity profiles along the aorta, we can target ...
Continuous Blood Pressure Variability within Young, Healthy Adults: A Test-Retest Study to Assess Relative and Absolute Reliability [0.03%]
青年健康成年人血压变异性连续监测的再测研究以评估其相对和绝对可靠性
Lydia E Valtadoros,David A Valdez Rendon,Carson A Newton et al.
Lydia E Valtadoros et al.
Variability in 24-hour and visit-to-visit blood pressure has been reported to be predictive of adverse cardiovascular outcomes. While recent studies have employed beat-to-beat blood pressure variability (BPV) as a predictor of cardiovascula...
Near-Infrared Spectroscopy Demonstrates Preserved and Reproducible Resting Skeletal Muscle Oxygenation Across Anatomical Sites in Stable Heart Failure [0.03%]
近红外光谱检测到稳定型心力衰竭患者不同解剖位点骨骼肌静息氧合保存且可重复性良好
Joanne Eng-Frost,Rohanti Ravikulan,Joel A De Pasquale et al.
Joanne Eng-Frost et al.
Background: Near-infrared spectroscopy (NIRS) enables non-invasive assessment of regional tissue oxygenation (StO2). Although impaired skeletal muscle oxygenation during stress is well documented in heart failure (HF), the reproducibility o...
Colin K L Phoon,Jeffrey A Ketterling
Colin K L Phoon
Sex-Specific Molecular Signatures of Reverse Remodeling After Aortic Valve Replacement [0.03%]
主动脉瓣置换术后反向重塑的性别特异性分子特征
Ganesh V Halade
Ganesh V Halade
Sleep restriction and cardiovascular disease risk: insights into potential mechanisms and sex differences [0.03%]
睡眠限制与心血管疾病风险:潜在机制及性别差异的见解
Daniel H Craighead,Ida T Fonkoue
Daniel H Craighead
Progranulin deficiency induces premature vascular senescence and dysfunction [0.03%]
粒细胞集落刺激因子缺乏诱发血管衰老及功能障碍
Renata de Azevedo Melo Luvizotto,Andre F Nascimento,Gustavo F Pimenta et al.
Renata de Azevedo Melo Luvizotto et al.
Significance: Cellular senescence-an age-associated state characterized by irreversible cell cycle arrest and pro-inflammatory signaling-contributes to vascular dysfunction and cardiovascular disease. However, the molecular mechanisms linki...
Left Ventricular Chamber Stiffness and Strain Determines the Myocardial Transcriptional Response to Elevated Filling Pressure [0.03%]
左心室腔僵硬度和应变决定心肌对充盈压升高的转录反应
Luke A Graser,Brian R Weil,Jeffrey C Miecznikowski et al.
Luke A Graser et al.
Transient hypertension precedes sustained hypertension and can arise from reduced aortic compliance with aging. We recently demonstrated that daily hypertension transients in swine rapidly lead to irreversible increases in left ventricular ...
COP9 signalosome deneddylation activity is required for proliferation but not dedifferentiation of vascular smooth muscle cells in neointimal hyperplasia [0.03%]
COP9信号肽体的去泛素化活性可促进新生内膜增生中血管平滑肌细胞的增殖而非去分化
Samiksha Giri,Xuejun Wang
Samiksha Giri
Neointimal hyperplasia (NH) is a prominent pathological consequence following vascular injury and is driven in part by aberrant vascular smooth muscle cell (VSMC) proliferation. COP9 signalosome (CSN) subunit 5 (CSN5/JAB1/COPS5) is the dene...
In vivo evidence of blood flow slippage: failure of the no-slip boundary condition assumption [0.03%]
体内血液滑移现象的实验证据:无滑移边界条件假设不成立
Alena Jarolímová,Jaroslav Hron,Karel Tůma et al.
Alena Jarolímová et al.
The assumption that blood adheres to vessel walls with zero tangential velocity component, the so-called "no-slip" boundary condition, is a foundational premise of cardiovascular fluid dynamics. Whether the no-slip condition holds in vivo, ...