Preserved diastolic carotid blood flow is associated with higher diastolic aortic pressure in lifelong female pearl divers [0.03%]
Rintaro Sakamoto,Tsubasa Tomoto,Daisuke Hoshi et al.
Rintaro Sakamoto et al.
Higher diastolic aortic pressure is associated with central arterial elastic recoil function and may help preserve peripheral perfusion. Japanese female pearl divers, called "Ama," exhibit lower arterial stiffness as an adaptation to lifelo...
Selective pharmacological blockade of GPR39 markedly reduces no-reflow and infarct volumes in rat acute myocardial infarction when administered before reperfusion [0.03%]
Carmen Methner,Mary Plascencia,Allura Thompson et al.
Carmen Methner et al.
Our aim was to determine whether selective pharmacological blockade of G protein-coupled receptor 39 (GPR39) by the novel drug, VC108, reduces no-reflow (NRV) and infarct (INV) volumes during acute myocardial infarction (AMI). Immunocytoche...
Validation of the detection of the salt sensitivity of blood pressure from 24-h ambulatory blood pressure monitoring data [0.03%]
基于动态血压监测数据的盐敏感性高血压筛查方法的验证研究
Xiangyu Zheng,Leonardo Máximo Cardoso,Christopher Dieffenthaller et al.
Xiangyu Zheng et al.
The salt sensitivity of blood pressure (SSBP) is rarely assessed and represents a critical barrier in precision hypertension treatment. The current approaches to assess salt sensitivity are labor- and resource-intensive, limiting their clin...
Tobacco and marijuana induce adverse effects on cardiac function and platelet activity and reduce tissue preservation following myocardial infarction [0.03%]
Xiaoyin Wang,Daniel D Han,Huiliang Qiu et al.
Xiaoyin Wang et al.
Smoking disrupts cardiac autonomic regulation, vascular biology, and platelet function; however, the acute and longer-term cardiovascular effects of resurging and emerging tobacco and marijuana products remain incompletely characterized. We...
Calcium handling in postinfarction arrhythmias: evidence from large animals [0.03%]
心梗后动物模型室性心律失常的钙稳态重建治疗研究进展
Tristan Hellstrand,Godfrey L Smith,Mathis Korseberg Stokke
Tristan Hellstrand
Understanding the causes of ventricular arrhythmias after myocardial infarction (MI) remains a major challenge to academic and clinical medicine. Key concepts in the pathophysiology underlying such events are based on studies in rodents, in...
Urinary UDP-sugars provide actionable prediction of acute kidney injury in cardiac surgery patients [0.03%]
尿液UDP糖类能预测心脏手术患者急性肾损伤
Christine Légaré,Patrick Caron,Mohammad M Al-Bataineh et al.
Christine Légaré et al.
Acute kidney injury (AKI) affects up to 50% of patients undergoing cardiopulmonary bypass, yet early diagnostic biomarkers and targeted therapies remain limited. Although AKI is attributed to bypass-induced renal ischemia, the underlying mo...
Age-Associated Patterns of Cardiovascular Risk and Disease Phenotypes Across Diverse Care Settings: The GLOB-cAGE Consortium [0.03%]
GLOB-cAGE联盟：不同医疗环境下心血管风险和疾病表型的年龄相关模式
Enyu Yang,Jie Sun,Yanhong Dong et al.
Enyu Yang et al.
Reported prevalence of cardiovascular disease (CVD) risk factors and phenotypes varies widely. In multi-cohort analyses, such variation reflects population risk, care setting, and data capture. We harmonized baseline data from four analytic...
Overlooked and ignored for too long: Investigation of regional and sex-related differences in vascular reactivity along the murine aorta [0.03%]
长久以来被忽视和忽略的：关于小鼠主动脉沿长度方向上血管反应性地区域性和性别差异的研究
Andrew P Braun,Michael A Hill
Andrew P Braun
A peripheral perspective on brain health: vascular and skeletal muscle contributions [0.03%]
从周边角度看待脑健康：血管和骨骼肌的贡献
Joshua L Keller,Kase J Pennartz,Justin D Sprick et al.
Joshua L Keller et al.
Age- and disease-related declines in brain health contribute to impairments in physical function, yet effective approaches to lessen these declines remain limited. Overall health is governed by a network of interdependent organ systems, suc...
A Cross-Sectional Analysis of Vascular Geometry in Adults: Associations of Age and Biological Sex with Iliofemoral Arterial and Venous Tortuosity [0.03%]
成人血管几何结构的横断面分析：年龄和生物性别与髂股动脉和静脉曲张的关系
Pauline M Berens,Benjamin C Liu,Arash Fereydooni et al.
Pauline M Berens et al.
Iliofemoral vascular tortuosity may reflect vascular aging, yet natural anatomic variation remains poorly characterized at scale. In this single-center retrospective study, we quantified arterial and venous iliofemoral tortuosity in a large...