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Selective pharmacological blockade of GPR39 markedly reduces no-reflow and infarct volumes in rat acute myocardial infarction when administered before reperfusion

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Our aim was to determine whether selective pharmacological blockade of G protein-coupled receptor 39 (GPR39) by the novel drug, VC108, reduces no-reflow (NRV) and infarct (INV) volumes during acute myocardial infarction (AMI). Immunocytochemistry and quantitat... ...