Mode of action (MOA) for nasal tumors induced by methyl isothiocyanate (MITC) in Sprague Dawley rats [0.03%]
甲基异硫氰酸酯(SD大鼠鼻肿瘤形成的致癌机制研究
Melissa Badding,B Bhaskar Gollapudi,Richard Reiss et al.
Melissa Badding et al.
Methyl isothiocyanate (MITC), a soil fumigant, induced nasal tumors in Sprague Dawley rats exposed by inhalation to a high concentration (20 ppm), but not at 0.5 or 5 ppm. In an inhalation study (1 day, 5 days, or 4 weeks) with MITC, nasal ...
Investigation of mode-of-action and human relevance of cumene-induced mouse liver tumors [0.03%]
丁基苯诱导的小鼠肝肿瘤的作用机制及对人类的相关性研究
Lynn H Pottenger,B Bhaskar Gollapudi,James S Bus
Lynn H Pottenger
Chronic inhalation exposure of mice to high concentrations of cumene resulted in liver tumors. The aim of this review was to investigate the mode of action (MOA) for these tumors and their relevance to humans. A pilot study demonstrated the...
Toxicological insights of silver nanoparticles biosynthesized from plant extracts of the Annonaceae family for control of insect vectors of pathogens: a systematic review [0.03%]
annonaceae植物提取物生物合成的银纳米颗粒控制病原体昆虫载体的毒理学见解：系统性综述
Julianne Soares Pereira,Rodolfo Osin de Moraes,Yasmim Leandro França Do Nascimento et al.
Julianne Soares Pereira et al.
Mosquito-borne diseases remain a major public health challenge, intensified by growing resistance to conventional insecticides. In this context, the green synthesis of silver nanoparticles (AgNPs), especially using plant extracts from the A...
How can academic researchers more effectively contribute to environmental toxicology and health efforts for regulatory decisions, policymakers, nonprofits, and communities? [0.03%]
学术研究人员如何更有效地为环境毒理学和卫生工作的监管决策、政策制定者、非营利组织和社区做出贡献？
Joel N Meyer,Elizabeth F Boxer,Kevin M Crofton et al.
Joel N Meyer et al.
Most ecological and human environmental health researchers are motivated both by curiosity and a desire to do work that will be useful sooner rather than later. However, the academic research process does not always produce and present resu...
A systematic review of environmentally persistent free radical (EPFR) formation, characteristics, and health effects: are there sufficient data for risk assessment? [0.03%]
环境持久性自由基（EPFR）的形成、特性及健康影响的系统评价：风险评估的数据是否足够？
Avinash Kumar,Divine Nde,Chuqi Guo et al.
Avinash Kumar et al.
Environmentally persistent free radicals (EPFRs) are stable free radicals formed on particulate matter (PM) through processes such as combustion and pyrolysis. These free radicals are generated on transition metal oxide surfaces in the pres...
Environmental and animal reservoirs of methicillin-resistant Staphylococcus aureus (MRSA): a One Health challenge [0.03%]
环境和动物甲氧西林耐药金黄色葡萄球菌(MRSA)的储存宿主：一个关于“同一健康”的挑战
Isabela Náthaly Machado da Silva,Marcelino Bemvindo-Souza,Carlos Filipe Camilo-Cotrim et al.
Isabela Náthaly Machado da Silva et al.
Methicillin-resistant Staphylococcus aureus (MRSA) is among the most prevalent nosocomial pathogens. However, in recent decades, infections were reported in communities, infecting individuals without previous hospitalization, and in livesto...
Underexplored terrain: effects of high priority environmental toxicants on skeletal muscle [0.03%]
亟待探索的领域：环境优先污染物对骨骼肌的影响
Zachary Clemens,Lauren Weaver,Abraham Brown et al.
Zachary Clemens et al.
In recent decades, evidence has continuously mounted regarding the myriad adverse health effects that environmental exposures exert on human health, yet little attention has been given to skeletal muscle-related outcomes. With its important...
Systematic review of adverse human health effects following oral exposure to inorganic nitrate and nitrite [0.03%]
无机硝酸盐和亚硝酸盐口服暴露对人类健康不利影响的系统评价
Krista Y Christensen,Paige A Bommarito,Rachel M Shaffer et al.
Krista Y Christensen et al.
Inorganic nitrate and nitrite are naturally occurring anions that play an essential role in Earth's nitrogen cycle. The general population is exposed to nitrate and nitrite from both food and drinking water sources. However, there is eviden...
Genotoxicity and mutagenicity of emerging mycotoxins: a systematic review [0.03%]
新兴霉菌毒素的遗传毒性和致突变性：系统综述
M Benito-Fuertes,A Rodríguez-Garraus,S Gascón-Corella et al.
M Benito-Fuertes et al.
The increasing detection of emerging mycotoxins in food and feed emphasizes the need to assess their potential adverse health risks. Unlike regulated compounds, many mycotoxins lack toxicological data, especially regarding genotoxicity or c...
Ecotoxicological risks and sustainability of integrated biopesticide-based approaches for Aedes aegypti control [0.03%]
基于生物农药的登革热媒介伊蚊综合控制法的生态毒理风险与可持续性研究
Vanessa Santana Vieira Santos,Boscolli Barbosa Pereira
Vanessa Santana Vieira Santos
The global spread of Aedes aegypti poses increasing challenges for vector control programs, especially in the context of insecticide resistance and growing environmental concerns. Innovative control strategies include integrated vector mana...