Underexplored terrain: effects of high priority environmental toxicants on skeletal muscle [0.03%]
亟待探索的领域：环境优先污染物对骨骼肌的影响
Zachary Clemens,Lauren Weaver,Abraham Brown et al.
Zachary Clemens et al.
In recent decades, evidence has continuously mounted regarding the myriad adverse health effects that environmental exposures exert on human health, yet little attention has been given to skeletal muscle-related outcomes. With its important...
Systematic review of adverse human health effects following oral exposure to inorganic nitrate and nitrite [0.03%]
无机硝酸盐和亚硝酸盐口服暴露对人类健康不利影响的系统评价
Krista Y Christensen,Paige A Bommarito,Rachel M Shaffer et al.
Krista Y Christensen et al.
Inorganic nitrate and nitrite are naturally occurring anions that play an essential role in Earth's nitrogen cycle. The general population is exposed to nitrate and nitrite from both food and drinking water sources. However, there is eviden...
Genotoxicity and mutagenicity of emerging mycotoxins: a systematic review [0.03%]
新兴霉菌毒素的遗传毒性和致突变性：系统综述
M Benito-Fuertes,A Rodríguez-Garraus,S Gascón-Corella et al.
M Benito-Fuertes et al.
The increasing detection of emerging mycotoxins in food and feed emphasizes the need to assess their potential adverse health risks. Unlike regulated compounds, many mycotoxins lack toxicological data, especially regarding genotoxicity or c...
Ecotoxicological risks and sustainability of integrated biopesticide-based approaches for Aedes aegypti control [0.03%]
基于生物农药的登革热媒介伊蚊综合控制法的生态毒理风险与可持续性研究
Vanessa Santana Vieira Santos,Boscolli Barbosa Pereira
Vanessa Santana Vieira Santos
The global spread of Aedes aegypti poses increasing challenges for vector control programs, especially in the context of insecticide resistance and growing environmental concerns. Innovative control strategies include integrated vector mana...
Database-calibrated toxicity values for human health assessment based on existing toxicology data for one thousand chemicals [0.03%]
基于现有毒理学数据的千种化学品人类健康风险评估毒性参数数据库校准值的研究
Alison H Harrill,Shintaro Hagiwara,Chelsea A Weitekamp et al.
Alison H Harrill et al.
The US Environmental Protection Agency (US EPA) and other regulatory agencies routinely assess whether certain chemical exposures might result in harmful health effects. Traditional human health assessments rely upon expert judgment of dose...
Human biomonitoring and environmental health: a critical review of global exposure patterns, methodological challenges and research gaps [0.03%]
人体生物监测与环境健康：全球暴露模式、方法论挑战及研究空白的批判性回顾
Eduardo de Paula Nunes,Badr Abou Dehn Pestana,Boscolli Barbosa Pereira
Eduardo de Paula Nunes
Human biomonitoring (HBM) is an essential approach for assessing exposure to environmental toxicants and for informing risk assessment frameworks. However, the global expansion of HBM has (1) outpaced efforts to harmonize methodologies, (2)...
Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs) [0.03%]
一组新型方法（NAM）测试全氟和多氟烷基物质（PFAS）库的见解
Grace Patlewicz,Richard Judson,Katie Paul Friedman et al.
Grace Patlewicz et al.
Per- and polyfluoroalkyl substances (PFAS) comprise a large class of human-made chemicals that are in widespread use and present concerns for persistence, bioaccumulation and toxicity. Whilst a handful of PFAS have been characterized for th...
Critical review of the association between environmental manganese and thyroid function, with implications for potential neurodevelopmental effects [0.03%]
环境锰与甲状腺功能关系的批判性评价及其对神经发育影响的启示
N Karyakina,N Shilnikova,N Farhat et al.
N Karyakina et al.
Manganese (Mn) is an essential trace element that, in excess, may initiate adverse health effects. Recent evidence suggested that environmental exposure to Mn may produce thyroid hormone imbalances leading to adverse neurodevelopmental outc...
T G Osimitz,W Droege
T G Osimitz
Quaternary ammonium compounds (QACs) are widely used to kill pathogenic microbes (including COVID-19), providing a substantial public health benefit. This review is an update to our previous publications that summarized and interpreted the ...
Jie Wang,Pengfei Guo,Yanfei Bian et al.
Jie Wang et al.
Morphine has been widely used to treat physical non-cancer pain as well as cancer-related pain. However, a growing body of evidence has emerged indicating that morphine in addition to alleviating pain initiates and suppresses immune functio...