Improved ESI-MS Sensitivity via an Imidazolium Tag (DAPMI-ITag) for Precise Sialic Acid Detection in Human Serum and CMAH-Null Mouse Tissues [0.03%]
通过咪唑
Yao-Yao Zhang,Zi-Xuan Hu,Si-Yu Zhang et al.
Yao-Yao Zhang et al.
Sialic acids (Sias), consisting primarily of N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc), play crucial roles in many biological processes. The detection and quantification of Sias are essential for understanding ...
Development of 68Ga-NOTA-cRGD Probe Mediated by Sulfenic Acid for Prolonging Tumor Imaging [0.03%]
通过亚硫酸盐介导的磺烯酸发展68Ga-NOTA-cRGD探针以延长肿瘤成像时间
Xinyu Xue,Wenfang Liao,Xiaotian Guo et al.
Xinyu Xue et al.
High reactive oxygen species (ROS) serve as important signaling molecules in the tumor microenvironment, and their excessive generation is closely associated with tumor growth, drug resistance, and metastasis of tumors. Rrecently, probes ba...
Construction of a Near-Infrared-Light-Triggered Dual-Signal Biosensing Platform for Microcystin-RR Detection Based on the Z-Type Heterojunction of Bi2S3/In(OH)3 [0.03%]
基于Bi₂S₃ / In(OH)₃ Z型异质结的近红外光触发微囊藻毒素-RR检测双信号生物传感平台的构建
Hanjie Dai,Kexin Zou,Shumin Zhang et al.
Hanjie Dai et al.
Traditional single-signal detection modes are susceptible to false positives and false negatives. In contrast, dual-signal detection modes enable the cross-validation of results, thereby enhancing detection accuracy. This study integrates n...
Quantitative Operando EPR Method on Redox-Active Ions in Electrode Materials: Considering the Conversion-Type Reactions as Examples [0.03%]
原位定量EPR研究电极材料中的氧化还原活性离子：以转化反应为例
Yi Liu,Xiang Wu,Xiaobing Lou et al.
Yi Liu et al.
Electron paramagnetic resonance (EPR), a sensitive probe for unpaired electron spins, has been widely used in the investigation of various electrochemical systems. Despite its success in studying electrochemical processes involving radicals...
Top-Down Characterization of Yeast tRNA by Gas-Phase Fractionation and Collisionally Activated Dissociation Informed by Electron Photodetachment Charge Reduction Mass Spectrometry [0.03%]
基于电子光解脱电荷减少质量测定的气体相分馏和碰撞激活解离自上而下表征酵母tRNA
Michael B Lanzillotti,Jessica Pauling,Thanh Nguyen et al.
Michael B Lanzillotti et al.
Many transfer RNAs (tRNAs) are heavily modified and exhibit high sequence heterogeneity, making them challenging targets for characterization. Tandem mass spectrometry can interrogate multiple covalent modifications present on a single type...
Lifu Duan,Zhaoji Guan,Zhile Yuan et al.
Lifu Duan et al.
Rapid detection of hydrogen (H2) is essential for industrial production and environmental monitoring. Beat frequency photoacoustic spectroscopy offers an inherent measurement speed of milliseconds but at the cost of sensitivity. To overcome...
Development of a Thiol-ene Microfluidic Chip for Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS) [0.03%]
用于氢/氘交换质谱(HDX-MS)的硫醇-烯微流控芯片的开发
Anton B Hansen,Rasmus R Svejdal,Jordan T Aerts et al.
Anton B Hansen et al.
Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is a powerful technique for analyzing the conformational dynamics of proteins. Using liquid chromatography coupled to mass spectrometry (LC-MS), the method achieves high sensitivity and...
In-Line Combustion System for the Measurement of δ13C-CH4 in Gas Reference Materials Using Optical Isotope Ratio Spectroscopy [0.03%]
基于光学同位素比率光谱法利用 inline 燃烧系统测量气体参考物中 δ13C-CH4 的值
Aimee Hillier,Eric Mussell-Webber,Emily Hopkinson et al.
Aimee Hillier et al.
Measurements of the stable carbon isotope ratio in methane (δ13C-CH4) are used in determining the source of CH4 emissions on local, regional, and global scales. To achieve the required level of data comparability for atmospheric monitoring...
Bin Ren
Bin Ren
Ions with Ions, Entities with Entities: A Proof-of-Concept Study Using the SELM-1 Yeast Certified Reference Material for Intra- and Extracellular Se Quantification via Single-Cell ICP-Mass Spectrometry [0.03%]
单细胞ICP-MS离子与离子、实体与实体：使用SELM-1酵母标准参考物质进行细胞内和细胞外硒定量的概念验证研究
Antonio Bazo,Eduardo Bolea-Fernandez,Ana Rua-Ibarz et al.
Antonio Bazo et al.
In this work, two novel nanoparticle (NP)-based calibration strategies, external calibration and a relative method, have been explored for single-cell ICP-mass spectrometry (SC-ICP-MS) analysis. The fundamental principle of these methods is...