DeepMIR: A Hybrid Convolutional Neural Network-Transformer Framework for Accurate Identification of Target Components from Mid-Infrared Spectra of Mixtures [0.03%]
DeepMIR：一种混合卷积神经网络-变压器框架 准确识别混合物中红外光谱的靶标成分
Lin Tan,Yue Wang,Hailiang Zhang et al.
Lin Tan et al.
Accurate identification of components from mid-infrared (MIR) spectra of mixtures remains a significant challenge in analytical chemistry due to severe spectral overlap and instrumental variability. To address this, we present DeepMIR, a de...
Time-Resolved "Barbecue" Förster Resonance Energy Transfer for Sensitive and Homogenous Detection of Alginate [0.03%]
时间分辨“烧烤”福尔哈德共振能量转移敏感均相检测琼脂糖醛酸
Anran Zhang,Xuanwei Mei,Qianqian Lyu et al.
Anran Zhang et al.
The development of glycoscience has been impeded by the inherent structural complexity of carbohydrates, the lack of template encoding, and the limitations of current methodologies for their identification and quantification. Carbohydrate-b...
Hierarchically Porous Amino-Functionalized Microporous Organic Networks Coated Fiber for Sensitive Breath Metabolite Profiling: A Noninvasive Strategy for Gastric Cancer Diagnosis [0.03%]
分级多孔氨基功能化微孔有机网络包覆纤维用于灵敏地分析呼吸代谢物：一种无创性胃癌诊断策略
Pengfei Li,Feiran Zhang,Hong Wang et al.
Pengfei Li et al.
The application of solid-phase microextraction (SPME) in breath metabolomics represents a promising strategy for noninvasive clinical disease diagnostics and comprehensive metabolic monitoring. Despite its potential, SPME faces several chal...
Recent Progress in Flexible Medical Sensors: Materials, Mechanisms, and Multifunctional Applications [0.03%]
近年来柔性医疗传感器的进展：材料、机制及多功能应用
Yingqing Yu,Qiushi Wang,Jiandong Cui et al.
Yingqing Yu et al.
Integrated Biomimetic Platform for Enhancing the Efficient Capture and Visual Identification of Circulating Tumor Cells [0.03%]
一种用于高效捕获和视觉识别循环肿瘤细胞的集成仿生平台
Tianyu Zeng,Ben Li,Jialin Xu et al.
Tianyu Zeng et al.
The nondestructive capture and direct identification of circulating tumor cells (CTCs) have emerged as the critical technologies in modern oncology for oncology research, clinical diagnosis, and personalized therapy optimization. However, t...
Orthogonal Biochemical Sensing for Concentration-Independent Bacterial Fingerprinting [0.03%]
正交生化传感在浓度无关细菌指纹识别中的应用
Xin Wang,Lilin Yin,Haiyan Li et al.
Xin Wang et al.
Array-based biosensors hold substantial promise for rapid bacterial identification. However, conventional approaches face two key limitations: their reliance on nonspecific interactions with bacterial surfaces hinders biochemical interpreta...
Combined Use of Engineered PfAGO and LbCas12a for Nucleic Acid Detection [0.03%]
工程化PfAGO和LbCas12a结合用于核酸检测
Wanting Zeng,Xiaochen Xie,Xiaolan Yu et al.
Wanting Zeng et al.
The COVID-19 pandemic has underscored the urgent need for rapid, accurate, and accessible nucleic acid detection technologies. Here, we present NAEPLS (Nucleic Acid Detection Based on Engineered PfAgo and LbCas12a with Split crRNA), a novel...
Calibrated Uncertainty Estimation for Soil Organic Carbon from Raman Spectra [0.03%]
拉曼光谱估算土壤有机碳的不确定性校准方法
Jeffrey K Wiens,Natalia Solomatova,Sadegh Shokatian
Jeffrey K Wiens
Machine learning (ML) is a powerful tool for inferring chemometric properties from Raman spectra, expanding the information extractable from high-dimensional spectral data. A growing application is the estimation of soil organic carbon (SOC...
Seawater Salinity Measurement Using Laser-Induced Plasma: Acoustic-Spectral Characteristics and Analytical Performances [0.03%]
基于激光诱导击穿光谱的海水盐度测量：声学-光谱特征及分析性能研究
Ye Tian,Qingxi Liu,Beibei Wang et al.
Ye Tian et al.
Seawater salinity is a critical parameter in marine environments; however, the established methods based on conductivity or refractive index detection can hardly obtain the elemental compositions of seawater that affect the salinity. In thi...
Combining Retip Retention Time Prediction with High-Resolution Mass Spectrometry: A Systematic Analysis of Schisandra chinensis- Evodia Conducted for the First Time [0.03%]
首次结合保留时间预测与高分辨质谱的五味子-胡椒药材系统分析方法学研究
Jiaqi Xu,Lincheng Bai,Tiantian Wang et al.
Jiaqi Xu et al.
Schisandra chinensis-Evodia Herbal Pair (SEHP) is one of the classic Chinese herbal formulas for treating Alzheimer's disease (AD), but its complex chemical composition renders traditional analytical methods inefficient. Retention time (RT)...