Assessing Acetyl-Coenzyme A Carboxylase Activity and Inhibition in Caenorhabtidis elegans Using a Partially Purified Protein Extract [0.03%]
基于部分纯化的蛋白提取物检测乙酰辅酶A羧化酶活性及其抑制作用
Gennaro Battaglia,Yamanappa Hunashal,Suma Gopinadhan et al.
Gennaro Battaglia et al.
Acetyl-coenzyme A carboxylase (ACC) catalyzes the ATP-dependent carboxylation of acetyl-CoA into malonyl-CoA, the first step in fatty acid biosynthesis. ACC is increasingly recognized as being crucial for energy metabolism, leading to its e...
Eutectic Point Determination of Type V Hydrophobic Octanoic Acid-Based Solvents by "Lock-Free" 1H and 13C NMR Self-Diffusion Experiments [0.03%]
锁自由核磁自扩散实验在V型辛酸基疏水电解液共晶点的确定中的应用研究
Emilie Thiery,Mervé Yagmur,Jean-Marc Nuzillard et al.
Emilie Thiery et al.
Deep eutectic solvents (DESs) constitute a peculiar class of solvents with specific properties and applications. DESs are classified into five different types (I-V). Unlike types I-IV, type V deep eutectic solvents are a novel class of sust...
Rapid MS-Based Single-Cell Analysis Assisted by Photochemical Derivatization in Living Cell Membranes Reveals Lipidomic Patterns with Located C═C Bonds [0.03%]
基于活细胞膜光化学衍生化的快速单细胞MS分析揭示了具有定位C=C键的脂质组学模式
Chunyan Liu,Xianzhe Wu,Qingxi Ma et al.
Chunyan Liu et al.
Traditional lipidomics methods are not well-suited for studying unsaturated lipids containing located C═C bonds in single cells. Here, we proposed a single-cell mass spectrometry (MS) platform assisted by a photochemical derivatization (PC...
Identification and Distribution of the Dietary Antioxidant Ergothioneine in Humans and Animal Models Combining NMR, RANSY, and MS Methods [0.03%]
结合NMR、RANSY和MS方法鉴定并分析人体及动物模型中的膳食抗氧化剂 ergothioneine的分布及含量
G A Nagana Gowda,Wentao Zhu,Vadim Pascua et al.
G A Nagana Gowda et al.
Ergothioneine (ERG), a unique, naturally occurring antioxidant of dietary origin, is gaining increasing attention due to its crucial roles in human health and diseases. Despite its significance, ERG is rarely detected in biospecimens by mas...
Microfluidic Electrochemical Impedance Sensor for Hematological Tests of Blood under Different Osmotic Conditions [0.03%]
不同渗透条件下血液学检验的微流体电化学阻抗传感器
Alexander Zhbanov,Ye Sung Lee,Minkook Son et al.
Alexander Zhbanov et al.
Blood tests are widely used to assess a patient's health status. Microfluidics, in combination with electrochemical impedance spectroscopy (MEIS), opens up great prospects for blood analysis. This study aimed to improve the MEIS blood tests...
Simple Alternative Approach to the Molybdenum Blue Method for Quantification and Speciation of Phosphate and Arsenate in Freshwater [0.03%]
一种简便的替代钼蓝法用于量化和鉴别淡水中的磷酸盐和砷酸盐的方法
Rihab Masmoudi,Carl Tripp
Rihab Masmoudi
The Molybdenum Blue Method (MBM) is the standard visible spectroscopic approach for the detection of phosphate in water. A major drawback of the MBM is that arsenate also reacts with the molybdate ion to produce the same peak in the visible...
To Spray or To Sublimate: Considerations for the Matrix Application of Three Common Positive Ion Mode Matrices [0.03%]
喷还是升华？三种常见正离子模式基质的应用考量
Ian Spears,Gabriella Lagdameo,Alyson Black et al.
Ian Spears et al.
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) is a powerful tool for imaging lipids, proteins, N-glycans, metabolites, and drugs in situ. A key step in MALDI MSI is matrix deposition, which must balance...
Voltage Switching on a Dual Nano-Electrospray/Atmospheric Pressure Chemical Ionization Platform Provides Higher Discrimination Power for Malaria Detection via Direct Infusion Mass Spectrometry [0.03%]
基于电压切换的双纳升电喷雾/大气压化学电离平台可增强直接进样质谱对疟疾检测的分辨能力
Riley Ferguson,Dmytro S Kulyk,Abraham K Badu-Tawiah
Riley Ferguson
Nanoelectrospray ionization (nESI) is a powerful ion source enabling direct mass spectrometry (MS) analysis of polar compounds in small volumes. The exposure of charged microdroplets derived from nESI to nonthermal plasma discharge allows t...
Knitting Organic Cage into Hyper Cross-Linked Polymers for the Efficient Capture of Fluoroquinolones in Pork Samples [0.03%]
有机笼编织到超交联聚合物中用于捕获猪肉样品中的氟喹诺酮类抗生素
Shuofeng Li,Ying Zhao,Zhi Li et al.
Shuofeng Li et al.
Considering the ubiquitous presence and hazardous effects of fluoroquinolone antibiotics (FQs), developing efficient methods for their detection has become imperative to safeguard human health. In this work, we synthesized a porous organic ...
Ion Transport through Differently Charged Nanoporous Membranes: From a Single Nanopore to Multinanopores [0.03%]
带不同电荷的纳米多孔膜中的离子输运：从中尺度单一纳米通道到多个纳米通道
Hongwen Zhang,Bowen Ai,Zekun Gong et al.
Hongwen Zhang et al.
Nanoporous membranes, leveraging their high-throughput characteristics, have been widely applied in fields such as molecular separation and energy conversion. Due to interpore interactions, besides the applied voltage and solution environme...