CRISPR/Cas12a-Based Electrogenerated Chemiluminescence Biosensing Platforms: Advancing Next-Generation Point-of-Care Testing [0.03%]
基于CRISPR/Cas12a的电化学发光生物传感平台：推进下一代即时检测技术
Shiyan Xu,Pan Liu,Jinjing Qin et al.
Shiyan Xu et al.
DYNAMIC: A Novel Software Implementation of a Kinetic Model of TaqMan PCR [0.03%]
DYNAMIC：TaqManPCR反应的Kinetic模型的新软件实现
Louis Kreitmann,Ye Mao,Ke Xu et al.
Louis Kreitmann et al.
Multiplex PCR is a key modality of nucleic acid amplification testing with growing applications in clinical diagnostics, especially in infectious diseases. Recent work has demonstrated that thermodynamic and kinetic information embedded in ...
Covalent Bridging Achieves Nanorestriction Enhanced Aggregation-Induced Electrochemiluminescence for 17β-Estradiol ECL Imaging-Assisted Dual-Mode ECL/EC Detection [0.03%]
共价桥接实现纳受限增强型聚集诱导电化学发光用于雌二醇的ECL成像辅助双模式ECL/EC检测
Hao Geng,Yuan Li,Zhuangzhuang Ru et al.
Hao Geng et al.
This study presents a novel dual-mode biosensor that integrates electrochemiluminescence (ECL) and electrochemical (EC) techniques for the ultrasensitive detection of 17β-estradiol (E2). The biosensor system employed 4',4″,4‴,4'‴-(ethen...
A Multi-Domain Affinity Metal Organic Polymer-MXene Heterostructure for Superior Advanced Antibody Separation [0.03%]
一种多域亲和金属有机聚合物-MXene异构体用于优异的先进抗体分离
Haoran Wang,Lan Liu,Tianbao Li et al.
Haoran Wang et al.
Accurate acquisition of antibody proteins plays a critical role in clinical therapy and biomedical application. Herein, a hierarchical heterostructure framework is engineered through the interfacial polymerization of a polyhedral oligomeric...
Glutaraldehyde-Cross-Linked Polyethylenimine Functionalized Tapered Fiber Interferometer for Ultrasensitive (Sub-nM) Detection of Copper Ions [0.03%]
用于超灵敏（亚纳米）铜离子检测的戊二醛交联聚乙烯亚胺功能化锥形光纤干涉仪
Lei Dai,Muyang Li,Minghui Chang et al.
Lei Dai et al.
This work presents a Mach-Zehnder interferometer (MZI) fiber-optic sensor functionalized with a glutaraldehyde (GA) cross-linked polyethylenimine (PEI) film for the ultrasensitive detection of copper ions (Cu2+) in aqueous environments. The...
Broadband Light Scattering to Characterize the Absorption Spectra of Brown Carbon Chromophores [0.03%]
宽带光散射表征棕色碳发色团吸收光谱特性
Malsha Amugoda,Pedro M De Allende,Bilal Shokoor et al.
Malsha Amugoda et al.
Aerosol particles that contain brown carbon (BrC) chromophores will absorb solar radiation, with important implications for their effects in the environment. Although UV/vis spectroscopy of bulk BrC samples can be used to characterize absor...
High-Affinity Three-Way Junction Aptamers for Sensing Cationic Polymyxin Antibiotics [0.03%]
高亲和力三链接头适配子用于阳离子多粘菌素类抗生素检测
Sihan Wang,Jiayi Liang,Zhanhui Wang et al.
Sihan Wang et al.
Polymyxins B and E (colistin) were historically the last-resort antibiotics for treating infections caused by multidrug-resistant Gram-negative bacteria. However, their narrow therapeutic windows and significant nephrotoxicity necessitate r...
Design of Histidine-Based Antifouling Zwitterionic Peptides for the Reliable Electrochemical Detection of Cortisol in High-Salinity Sweat [0.03%]
一种组氨酸衍生物抗污两性离子多肽及其在高盐汗液中可靠检测皮质醇中的应用
Xiujuan Qiao,Rui Han,Guangyan Xu et al.
Xiujuan Qiao et al.
The reliable detection of cortisol in sweat presents a promising, noninvasive approach for stress monitoring. However, in demanding scenarios such as firefighting and mining, rapid sweat evaporation concentrates salts to high levels that de...
Fluorescence Machine Vision-Based Rapid Quantitative Characterization of Microplastics [0.03%]
基于荧光机器视觉的微塑料快速定量表征方法研究
Qiannan Duan,Hailong Zhang,Jiaqing Tang et al.
Qiannan Duan et al.
Rapid detection of microplastics (MPs) is crucial for reducing their risks to the environment and human health. Recently, advanced optical technologies such as Fourier transform infrared spectroscopy and Raman spectroscopy, combined with ar...
Fiber-Optic Interference Microscopy for Label-Free Monitoring of Cancer Cell Secretion at a Single-Molecule Level [0.03%]
基于光纤干涉的无标记单分子细胞分泌检测技术
Guoquan Wang,Yunli Peng,Guifeng Li et al.
Guoquan Wang et al.
Understanding cell secretion at the single-molecule level in a label-free manner is crucial for elucidating numerous biological processes relevant to health and disease. However, most current optical label-free approaches rely on strong pho...