Tandem MICROFASP Method-Enabled High-Sensitivity In Vivo Cross-Linking Mass Spectrometry Analysis of Low-Cell-Number Samples without Enrichment
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Cross-linking mass spectrometry (XL-MS) has emerged as an indispensable tool for dissecting protein conformations and protein-protein interactions (PPIs) within native biological systems. However, conventional in vivo XL-MS workflows suffer from significant sa... ...
