Optimisation of heat reflux extraction of gallic acid, quercetin and chlorogenic acid from Stevia rebaudiana (Bertoni) leaves by using response surface methodology and adaptive neuro-fuzzy inference system modelling [0.03%]
响应面法和自适应神经模糊推理系统建模优化从Stevia rebaudiana (Bertoni)叶中提取棓酸、山柰酚和氯ogenic酸
Devendra Kumar Pandey,Tuyelee Das
Devendra Kumar Pandey
Stevia rebaudiana Bertoni, belongs to the Asteraceae family is a perennial shrub and widely recognised as a natural sweetener. This plant contains steviol glycosides and antioxidant-rich phytoconstituents. However, optimisation of extractio...
Cannabinol derivatives, a new series of α-glucosidase inhibitors: synthesis, structure-activity relationship, and kinetic study [0.03%]
一类新的大麻酚衍生物α-葡萄糖苷酶抑制剂：合成、构效关系及动力学研究
Anh-Khoa Nguyen,Reza Setiawan,Sumrit Wacharasindhu et al.
Anh-Khoa Nguyen et al.
A new series of cannabinol derivatives was synthesised and assessed for their inhibitory effects against α-glucosidase. Of nineteen derivatives evaluated, the brominated analogues (3a and 3b) demonstrated the most potent inhibition against...
Molecular docking, simulation and ADMET studies of phenolic compounds from olive oil against main protease and RNA-dependent RNA polymerase of SARS-CoV-2 [0.03%]
橄榄油酚类化合物分子对接、模拟及ADMET研究对抗SARS-CoV-2的主要蛋白酶和RNA依赖性RNA聚合酶
Aziz Bouymajane,Soumia Moujane,Fouzia Rhazi Filali et al.
Aziz Bouymajane et al.
Plant extracts exhibit notable anti-SARS-CoV-2 potential due to their richness in biologically active phenolic compounds. This study aimed to evaluate the inhibitory activity of phenolic constituents from Morocco Picholine virgin olive oil ...
Chemical characterisation of the essential oils of three Baccharis species: Baccharis pentodonta Malme, Baccharis tridentata Vahl, and Baccharis linearifolia Pers [0.03%]
三种 Baccharis 植物的精油化学特征：Baccharis pentodonta Malme、Baccharis tridentata Vahl 和 Baccharis linearifolia Pers.
Adriana Rute Cordeiro,Raquel Endler Simioni,Domingos Sávio Nunes
Adriana Rute Cordeiro
Baccharis species (Asteraceae) are widely used in South American traditional medicine and produce essential oils rich in bioactive terpenoids. This study investigated the chemical composition of essential oils from leaves and inflorescences...
Flavonoid-rich fraction of Cyclocarya paliurus enhances osteogenic differentiation through the PI3K-AKT signaling pathway in MC3T3-E1 cells [0.03%]
铜陵胡桃黄酮诱导MC3T3-E1成骨分化的活性及其机制研究
GaoXiang Zhu,Rao Xiong,Zhao Yang et al.
GaoXiang Zhu et al.
Four types of macroporous resins (HPD-600, AB-8, D-101, and DM130) and a polyamide resin were compared for efficiency to extract total flavonoids from Cyclocarya paliurus (Batal.) Iljinskaja (CPF). Among them, HPD-600 was identified as the ...
Non-targeted NMR chemical profiling of vegetable oils: a two-path workflow for fast access to a detailed metabolome [0.03%]
基于NMR的植物油化学指纹图谱非靶向代谢组学快速分析方法研究
Anaïs Cyatwa,Joseph Thiery,Agathe Martinez et al.
Anaïs Cyatwa et al.
Vegetable oils are increasingly used to formulate bioactive ingredients with pharmaceutical, nutraceutical or cosmeceutical applications. Their biological properties depend directly on their chemical profile, but so far it remains difficult...
Expedient MPLC-based isolation of lupane triterpenoids from Glochidion zeylanicum var. tomentosum (Dalzell) Trimen. Bark [0.03%]
从Glochidion zeylanicum var. tomentosum(Dalzell)Trimen树皮中利用MPLC快速分离狼毒素三萜类化合物
Harshal S Patil,K S Jagadeesha,Ashwini Sanjay Baviskar et al.
Harshal S Patil et al.
An automated medium-pressure liquid chromatography (MPLC) system was employed for the preparative-scale isolation of lupane-type triterpenoids from Glochidion zeylanicum var. tomentosum (Dalzell) Trimen. Seven compounds were isolated and id...
Diterpenoids in Burnatia enneandra micheli (alismataceae) are active constituents by demonstrating its antibacterial activities [0.03%]
Burnatia enneandra micheli (alismataceae)中的二萜类化合物通过展示其抗菌活性为有效成分
Honoré Wangso,Gaetan Bayiha Ba Njock,Alphonse Laya et al.
Honoré Wangso et al.
Burnatia enneandra was traditionally used across the world for medicinal purposes. In Cameroon, this plant treats injuries, stomach aches and some intestinal parasites. Therefore, the bioactive molecules responsible for these potentials and...
Three novel benzophenones from Mesua caudata (King) Kosterm. and their cytotoxic activity [0.03%]
Mesua caudata（King）Kosterm。中的三种新型苯并菲酮及其细胞毒性作用
Mulyadi Tanjung,Muhammad Fajar Aldin,Ali Rohman et al.
Mulyadi Tanjung et al.
To clarify the cytotoxic potential of Mesua caudata (King) Kosterm., three novel benzophenone derivatives, mesucaudatins A-C (1-3), along with one known xanthone compound (4), were found in the stem bark of this plant. The structure determi...
Comprehensive chemical profiling and in silico analysis of bioactive metabolites from the unexplored medicinal plant Koenigia mollis [0.03%]
药用植物Koenigia mollis的综合化学谱分析及生物活性代谢物的分子机制研究
Mengukhrienuo Kuotsu,Gaijuliu Gaijuliu,T Tiakaba Jamir et al.
Mengukhrienuo Kuotsu et al.
Koenigia mollis, an underexplored traditional medicinal plant (MP) from Nagaland, was investigated for its phytochemical composition with emphasis on characterisation of bioactive constituents. Metabolic profiling was conducted using prelim...