Leveraging adrenergic receptor blockade for enhanced nonalcoholic fatty liver disease treatment via a biomimetic nanoplatform [0.03%]
利用类生物学纳米平台阻断肾上腺素受体治疗非酒精性脂肪肝病的研究
Bingyuan Fei,Yuewu Zhao,Jine Wang et al.
Bingyuan Fei et al.
Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation, steatosis and fibrosis. Sympathetic nerves play a critical role in maintaining hepatic lipid homeostasis and regulating fibrotic progression through ...
Responsive porous microneedles with riboflavin ocular microinjection capability for facilitating corneal crosslinking [0.03%]
一种具有核黄素眼部微量注射能力的可变形多孔微针用于促进角膜交联
Xiaojun Hu,Bin Kong,Yunzhe Wang et al.
Xiaojun Hu et al.
Riboflavin-5-phosphate (riboflavin) is the most commonly used photosensitizer in corneal crosslinking (CXL); while its efficient delivery into the stroma through the corneal epithelial barrier is challenging. In this paper, we presented nov...
miR-NPs-RVG promote spinal cord injury repair: implications from spinal cord-derived microvascular endothelial cells [0.03%]
miR-NPs-RVG促进脊髓损伤修复：源自脊髓的微血管内皮细胞的启示
Chao Li,Zhenyang Xiang,Mengfan Hou et al.
Chao Li et al.
Background: Spinal cord injury (SCI) often leads to a loss of motor and sensory function. Axon regeneration and outgrowth are key events for functional recovery after spinal cord injury. Endogenous growth of axons is asso...
Photoactive nanocatalysts as DTT-assisted BSA-AuNCs with enhanced oxidase-mimicking ability for sensitive fluorometric detection of antioxidants [0.03%]
一种基于DTT辅助的BSA-AuNCs纳米催化剂的模拟氧化酶在荧光检测抗氧化剂中的应用研究
Sanskruti Swain,Ting-Yi Lin,I-Hsuan Chou et al.
Sanskruti Swain et al.
Redox imbalance and oxidative stress are increasingly recognized as significant factors in health disorders such as neurodegenerative disorders, premature aging and cancer. However, detecting antioxidant levels that is crucial for managing ...
Redox-manipulating nanocarriers for anticancer drug delivery: a systematic review [0.03%]
用于抗癌药物输送的红氧操纵纳米载体：系统性综述
Xuan Meng,Yongli Shen,Huanyu Zhao et al.
Xuan Meng et al.
Spatiotemporally controlled cargo release is a key advantage of nanocarriers in anti-tumor therapy. Various external or internal stimuli-responsive nanomedicines have been reported for their ability to increase drug levels at the diseased s...
Ethosomes-mediated tryptanthrin delivery as efficient anti-psoriatic nanotherapy by enhancing topical drug absorption and lipid homeostasis [0.03%]
以角鲨烷为载体的喜树素抗银屑病纳米药物传输体系的研究及其作用机制探讨
Pengyu Wang,Shihao Hong,Can Cao et al.
Pengyu Wang et al.
Psoriasis is a chronic, relapsing, and refractory immune-mediated skin disease with the etiology and pharmaceutical targets remaining unsatisfactorily addressed. Topical herbal-derived compounds, such as tryptanthrin (Tryp), have been consi...
Bei Li,Chen Qi,Yifan Zhang et al.
Bei Li et al.
Kidney diseases represent a diverse range of conditions that compromise renal function and structure which characterized by a progressive deterioration of kidney function, may ultimately necessitate dialysis or kidney transplantation as end...
β-Cyclodextrin-optimized supramolecular nanovesicles enhance the droplet/foliage interface interactions and inhibition of succinate dehydrogenase (SDH) for efficient treatment of fungal diseases [0.03%]
优化的超分子纳米囊泡增强液滴/叶界面相互作用和琥珀酸脱氢酶（SDH）抑制以有效治疗真菌病
Deng-Xuan Guo,Li Song,Jing-Han Yang et al.
Deng-Xuan Guo et al.
Background: Plant fungal diseases present a major challenge to global agricultural production. Despite extensive efforts to develop fungicides, particularly succinate dehydrogenase inhibitors (SDHIs), their effectiveness ...
Encapsulated lactiplantibacillus plantarum improves Alzheimer's symptoms in APP/PS1 mice [0.03%]
包被的植物乳杆菌改善APP / PS1小鼠阿尔茨海默病症状
Fangfang Hu,Qian Gao,Caiyun Zheng et al.
Fangfang Hu et al.
Background: Alzheimer's disease (AD) is a neurodegenerative disorder that can result in neurotoxicity and an imbalance in gut microbiota. Probiotics have been shown to play an important role in regulating the gut microbio...
An antimicrobial microneedle patch promotes functional healing of infected wounds through controlled release of adipose tissue-derived apoptotic vesicles [0.03%]
一种抗菌微针贴片通过控制释放脂肪组织来源的凋亡小体促进感染伤口的功能愈合
Yue Ma,Jia Dong,Maojiao Li et al.
Yue Ma et al.
The high incidence and mortality rates associated with acute and chronic wound infections impose a significant burden on global healthcare systems. In terms of the management of wound infection, the reconstruction and regeneration of skin a...