Correction: Transcranial and precise optical neuromodulation mediated by NIR photoactive nanosheets [0.03%]
Deqi Yang,Ya Zhang,Yun Yuan et al.
Deqi Yang et al.
Published Erratum
Journal of nanobiotechnology. 2026 Jan 2;24(1):2. DOI:10.1186/s12951-025-03886-x 2026
Covalent organic framework-based electrochemical nanosensing: an emerging paradigm for early cancer diagnosis and longitudinal surveillance [0.03%]
基于共价有机框架的电化学纳米传感：一种新兴的癌症早期诊断和长期监测范式
Yue Zhang,Shuyi Chen,Jie Ma et al.
Yue Zhang et al.
The management of cancer relies crucially on early diagnosis and personalized treatment. Real-time analysis of tumor markers within the tumor microenvironment via liquid biopsy opens potential pathways for effective cancer treatment and imp...
β-Carotene liposome-based responsive hydrogel inhibits palmitoylation to restore intracellular calcium homeostasis for effective periodontitis treatment [0.03%]
基于β-胡萝卜素脂质体的响应性水凝胶通过抑制棕榈酰化恢复细胞内钙稳态以有效治疗牙周炎
Shun Huang,Menghan Li,Zishuo Cheng et al.
Shun Huang et al.
Endoplasmic reticulum (ER) stress is a key pathological mechanism in periodontitis. Our study demonstrates that the periodontitis microenvironment induces ER stress, leading to ER Ca2+ efflux via inositol 1,4,5-trisphosphate receptors (IP3R...
Electrically stimulated asymmetric double-layer scaffolds using 3D printing and electrospinning for enhanced bacteria-free wound healing application [0.03%]
基于3D打印和静电纺丝的电刺激不对称双层支架用于抗菌创面修复应用
Jieun Lee,Aayushi Randhawa,Hyeonseo Park et al.
Jieun Lee et al.
Wound healing is a complex process that can be severely impaired in chronic or infected wounds. To overcome these challenges, we developed a bioinspired, double-layer asymmetric hydrogel scaffold combining a conductive hydrogel with an anti...
pH-triggered Mn-ZIF8 nanoreactor enhances tumor immunotherapy by amplifying the cGAS-STING pathway through a self-reinforcing gas-metal synergy strategy [0.03%]
基于自强化气体-金属协同策略的pH触发Mn-ZIF8纳米反应器通过放大cGAS-STING通路增强肿瘤免疫治疗
Ziyi Wu,Guangyao Jiang,Zhijie Jiang et al.
Ziyi Wu et al.
Although conventional immunotherapies have significantly transformed cancer treatment, their efficacy is still fundamentally limited by the immunosuppressive tumor microenvironment and systemic toxicity. In this study, we propose a Gas-Meta...
Biomimetic cell membrane decorated calcium carbonate nanoparticles with asparaginase-metformin preloading for leukemia therapy [0.03%]
用于白血病治疗的生物膜装饰碳酸钙纳米颗粒联合阿斯帕гин酶-二甲双胍载药体系
Guangtao Gao,Junyi Che,Bing Chen et al.
Guangtao Gao et al.
Chemotherapy is the primary clinical treatment for leukemia, while its effectiveness is often limited due to undesired off-target effects and the reduced sensitivity of leukemia cells to chemotherapeutic agents. Therapies capable of targeti...
Engineering endoplasmic reticulum targeted metal-polyphenol curcumin nanomicelles for melanoma therapy [0.03%]
工程内质网靶向金属-多酚纳米胶束用于黑色素瘤治疗中的姜黄素研究
Yixun Zhang,Xuehua Wang,Hongli Zhang et al.
Yixun Zhang et al.
Melanoma has a high incidence and mortality, and current therapies are limited. Here, we developed TCPC, an ER-targeted nanomedicine guided by omics analysis. It consists of curcumin-loaded PEG-PCL nanomicelles coated with a Tannic acid-Cu ...
H2S-responsive CuSe nanoparticles convert into CuSSe in situ with band gap modulation for oxygen self-supply and enhanced colon cancer phototherapy [0.03%]
一种新型的CuSe纳米粒子在肿瘤微环境中可转化为CuSSe并原位产生氧气以促进近红外光动力治疗
Manoj Kandel,Arjun Sabu,Kai-Min Chan et al.
Manoj Kandel et al.
Colorectal cancer (CRC) remains a significant challenge due to its aggressive nature and propensity for metastasis. This study presents a novel approach to CRC treatment by improved photothermal/photocatalytic/chemodynamic combination thera...
131I/MTX-loaded engineered outer membrane vesicles for sequentially coordinated radio-metabolic-immunotherapy of glioma [0.03%]
载有131I/MTX的工程化外膜囊泡用于胶质瘤的序贯同位素-代谢-免疫治疗
Maolin Liang,Longfei Fan,Suming Zhang et al.
Maolin Liang et al.
The efficacy of radiotherapy for brain tumors is limited by tumor cell radio-resistance and the immunosuppressive microenvironment, which often counteracts the immunogenic effects of radiation-induced antitumor responses. To address this, w...
An oral engineered cerium-peptide composite microsphere inhibits inflammatory bowel disease and reverses chronic fibrosis [0.03%]
一种口服工程化铈-肽复合微球可抑制肠炎并逆转慢性纤维化
Wenyu Qiao,Luling Yang,Yu Liu et al.
Wenyu Qiao et al.
Excessive accumulation of reactive oxygen species (ROS) and dysbiosis of the gut microbiota are pivotal contributors to the pathogenesis of inflammatory bowel disease (IBD) and associated fibrosis. In this study, a microfluidic approach was...