Surface engineering of extracellular vesicles: trends, strategies, and applications in diagnosis and therapy [0.03%]
Yanhang Hong,Shi Hu,Zitong Yu et al.
Yanhang Hong et al.
Extracellular vesicles (EVs) have emerged as pivotal mediators of intercellular communication, offering exceptional biocompatibility and an innate ability to cross biological barriers. These properties make them highly attractive for therap...
The interplay between autophagy and immunogenic cell death: nanomaterial-based strategies for cancer immunotherapy [0.03%]
Mehdi Khorrami,Mahmood Fadaie,Saeid Razavi Dizaji et al.
Mehdi Khorrami et al.
Cancer immunotherapy has significantly advanced the field of oncology. However, effectiveness of immunotherapy remains limited by tumor heterogeneity, immune evasion, and immunosuppressive tumor microenvironments. Immunogenic cell death (IC...
Unlocking caspase-8 enables Pt(IV) to trigger robust caspase-3/GSDME-mediated pyroptosis via drug co-delivery in chemoresistant bladder cancer [0.03%]
Jintao Wen,Baotong Zhou,Hanchen Zhang et al.
Jintao Wen et al.
Overcoming profoundly suppressed programmed cell death and an immunosuppressive tumor microenvironment (TME) remains a formidable challenge in gemcitabine-cisplatin-resistant muscle-invasive bladder cancer (GP-R MIBC). To address this, we d...
Therapeutic potential of ADAR1-regulated macrophage exosomes for improving myocardial damage in septic cardiomyopathy [0.03%]
Linxiao Wang,Shanshou Liu,Xianqi Wang et al.
Linxiao Wang et al.
Background: Sepsis-induced cardiomyopathy (SICM) is a critical cardiovascular complication characterized by cardiac dysfunction and high mortality. The molecular mechanisms that underlie SICM remain elusive, and effective...
Mechanistic insights into mRNA-LNP interactions: role of ionizable lipid content in regulating mRNA intracellular release and translation [0.03%]
Hoang Quan Truong,Urmila Kafle,Cao Thuy Giang Nguyen et al.
Hoang Quan Truong et al.
Messenger RNA (mRNA) therapeutics rely on lipid nanoparticles (LNPs) for effective intracellular delivery, yet the intracellular release of mRNA from these carriers remains an underexplored barrier to translation. In this study, we investig...
Bee sting-shaped microneedles for accelerating Achilles tendinopathy healing via enhanced regulating macrophage polarization [0.03%]
Muwei Hao,Kai Xiang,Keyi Zhang et al.
Muwei Hao et al.
Achilles tendinopathy (AT) is a common overuse injury to the Achilles tendon, and its progression is closely associated with an imbalance in M1/M2 macrophages and the inflammatory microenvironment. Traditional AT treatments are often limite...
NIR-II photothermal-amplified triple catalysis of a spherical mesoporous iron single-atom nanozyme for potentiating ferroptosis-based tumor therapy [0.03%]
Jingting Li,Sihan Wang,Fan Yang et al.
Jingting Li et al.
Background: Single-atom nanozymes (SAzymes) generally trigger catalytic reactions in situ within tumor cells, generating toxic reactive oxygen species (ROS) that induce cell death through oxidative stress, thereby achievi...
Correction: Regulation of immune microenvironments by polyetheretherketone surface topography for improving osseointegration [0.03%]
Yuqing Zhao,Yanxin An,Fan Wu et al.
Yuqing Zhao et al.
Published Erratum
Journal of nanobiotechnology. 2026 Apr 10;24(1):336. DOI:10.1186/s12951-026-04299-0 2026
Correction: Transdermal delivery of CRISPR/Cas9-mediated melanoma gene therapy via polyamines-modified thermosensitive hydrogels [0.03%]
Meng Li,Songli Zhou,Suqin Zhang et al.
Meng Li et al.
Published Erratum
Journal of nanobiotechnology. 2026 Apr 10;24(1):340. DOI:10.1186/s12951-026-04247-y 2026