Rapid diagnostic imaging and targeted immunotoxin delivery in aggressive prostate cancer using CEACAM5-specific nanobodies [0.03%]
采用CEACAM5特异性纳米抗体快速诊断成像及靶向免疫毒素递送治疗侵袭性前列腺癌
Zhaoming Xiao,Jingbo Ma,Jinpeng Cen et al.
Zhaoming Xiao et al.
Aggressive variant prostate cancer (AVPC) originates from metastatic prostate cancer (mPCa) following androgen receptor-targeted therapies, leading to diverse pathological subtypes, notably castration-resistant prostate cancer (CRPC). Carci...
Enhancing the potency of 5T4 mRNA vaccine by CD70 mRNA-LNPs through ADCC and T cell boosting in prostate cancer therapy [0.03%]
通过ADCC和T细胞增强提高CD70 mRNA-LNPs联合5T4 mRNA疫苗在前列腺癌治疗中的疗效
Fei Cao,Yuandong Xu,Yupeng Guan et al.
Fei Cao et al.
Background: Prostate cancer remains a significant health challenge, as conventional treatments often fail to provide long-term benefits in the advanced stages. This study explored the potential of mRNA vaccines as novel t...
Lyophilized apoptotic vesicles restore DNA damage and mitochondria dysfunction to ameliorate radiation enteritis [0.03%]
冻干的凋亡小体通过修复辐射诱发的肠道黏膜DNA损伤和线粒体功能障碍治疗放射性肠炎
Bo Yang,Huigen Luo,Xutong Yan et al.
Bo Yang et al.
Radiation therapy for malignant tumor patients often induces radiation enteritis (RE), a condition that impairs their quality of life. Currently, there is no standard treatment regimen available. In this study, we used lyophilized apoptotic...
Efficacy and safety of Fe-curcumin coordination polymer nanodots to prevent corneal neovascularization in alkali burn models [0.03%]
铁-姜黄素配位聚合物纳米点预防碱烧伤模型角膜新生血管化的有效性和安全性
Yan Huo,Lele Song,Zhihui Han et al.
Yan Huo et al.
Alkali burns pose a significant risk of corneal injury, leading to potential blindness. During the progression of alkali burns, heightened oxidation levels can induce corneal damage, resulting in diminished clarity and vision loss. In this ...
Exosomes derived from platelet-rich plasma alleviate synovial inflammation by enhancing synovial lymphatic function [0.03%]
富血小板血浆衍生的外泌体通过增强滑膜淋巴功能来缓解滑膜炎症
Bo Liao,Yu Tian,Mengtong Guan et al.
Bo Liao et al.
Background: Synovial inflammation is a pivotal factor in the pathogenesis of osteoarthritis (OA). Platelet-rich plasma-derived Exosomes (PRP-Exos), known for their low immunogenicity, have demonstrated efficacy in modulat...
Carrier-free nano-integrated strategy of phototherapy and chemotherapy for synergetic AKT targeted therapy to inhibit cancer metastasis and recurrence [0.03%]
一种用于协同靶向AKT治疗的无载体纳米集成光化疗策略以抑制癌症转移和复发
Zhuoting Lu,Tong Wang,Xiangchi Xu et al.
Zhuoting Lu et al.
A key challenge in clinical anticancer treatments is metastasis and recurrence, to address this challenge, it is crucial to develop combination treatment strategies that target different molecular pathways, considering the high complexity o...
CXCL12-targeting siRNA nanoparticles alleviate immunosuppression and inhibit tumor progression in esophageal squamous cell carcinoma [0.03%]
针对CXCL12的siRNA纳米颗粒可缓解食管鳞癌免疫抑制并抑制肿瘤进展
Shuyao Zhang,Hong Jiang,Chengkuan Zhao et al.
Shuyao Zhang et al.
Esophageal squamous cell carcinoma (ESCC) is associated with a highly immunosuppressive tumor microenvironment (TME), driven in part by cancer-associated fibroblasts (CAFs) that promote immune evasion through the secretion of CXCL12. CXCL12...
Correction to: Light-triggered multifunctional nanoplatform for efficient cancer photo-immunotherapy [0.03%]
Correction to：用于高效癌症光免疫治疗的光触发多功能纳米平台
Juan Yue,Qian Mei,Panyong Wang et al.
Juan Yue et al.
Published Erratum
Journal of nanobiotechnology. 2025 Jul 16;23(1):517. DOI:10.1186/s12951-025-03584-8 2025
Unveiling new therapeutic targets for esophageal cancer treatment through single-cell transcriptomics: pH-responsive nanobubbles enhance the efficacy of 125I radiotherapy [0.03%]
单细胞转录组学揭示新的反流性食管癌治疗靶点：pH响应型纳米气泡增强¹²⁵I放射治疗疗效
Yiliang Wang,BangHua Zhong,Xiaoyu Chen et al.
Yiliang Wang et al.
Correction: Multi-enzymatic biomimetic cerium-based MOFs mediated precision chemodynamic synergistic antibacteria and tissue repair for MRSA-infected wounds [0.03%]
Correction: 多酶仿生铈基MOF介导的精确化学动力学协同抗菌及组织修复以治疗耐甲氧西林金黄色葡萄球菌感染伤口
Shiqi Chen,Yifan Li,Qiang Ma et al.
Shiqi Chen et al.
Published Erratum
Journal of nanobiotechnology. 2025 Jul 15;23(1):516. DOI:10.1186/s12951-025-03547-z 2025