Self-supplying hydrogen peroxide-driven gold nanoparticle aggregation via bio-orthogonal click reaction activates cGAS-STING-PERK pathway for multimodal tumor therapy
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We developed an effective nanoplatform, T+EPAuNPLu&Lap, that concurrently harnesses Type I photodynamic therapy (PDT), chemodynamic therapy (CDT), photothermal therapy (PTT), and immunomodulation to remodel the immunosuppressive tumor microenvironment (TME). B... ...
