RGD-HSA-TAC nanoparticles targeted delivery of tacrolimus and attenuation of podocyte injury in diabetic kidney disease [0.03%]
RGD-HSA-TAC纳米颗粒靶向递送他克莫司并减轻糖尿病肾脏疾病中的足细胞损伤
Zhaochen Guo,Shaohui Gao,Feng Xu et al.
Zhaochen Guo et al.
Background: Diabetic kidney disease (DKD) is a prevalent and severe complication of diabetes and plays a pivotal role in the pathogenesis and progression of DKD. However, the current clinical application of the treatment ...
Cross-protection against homo and heterologous influenza viruses via intranasal administration of an HA chimeric multiepitope nanoparticle vaccine [0.03%]
通过鼻内给药的HA嵌合多抗原纳米颗粒疫苗对同源和异源流感病毒的交叉保护作用
Yongqiang Zhao,Jia Liu,Chun Peng et al.
Yongqiang Zhao et al.
Background: Influenza A viruses (IAVs) cause seasonal influenza epidemics and pose significant threats to public health. However, seasonal influenza vaccines often elicit strain-specific immune responses and confer little...
Astaxanthin-loaded brain-permeable liposomes for Parkinson's disease treatment via antioxidant and anti-inflammatory responses [0.03%]
一种可用于治疗帕金森病的虾青素脑渗透脂质体抗氧化抗炎响应研究
Thai-Duong Nguyen,Shristi Khanal,Eunhee Lee et al.
Thai-Duong Nguyen et al.
Parkinson's disease is a neurodegenerative disorder characterized by cardinal motor symptoms resulting from the loss of dopaminergic neurons in the substantia nigra pars compacta. Although current medications may alleviate its symptoms, Par...
Enhanced penetration and biofilm eradication by sophorolipid micelles encapsulating Honokiol: a comprehensive solution for biofilm-associated lung infections [0.03%]
壳寡糖包封的石松烯 Sophorolipid 多糖胶纳米粒增强渗透及生物膜根除作用：一种治疗肺部生物被膜相关感染的有效方法
Shiyu Lin,Xiaojuan Li,Wei Zhang et al.
Shiyu Lin et al.
Background: Biofilm-associated lung infections, particularly those caused by Staphylococcus aureus (S. aureus), pose significant clinical challenges to conventional therapies. S. aureus Biofilm infections are refractory t...
Simultaneously delivery of functional gallium ions and hydrogen sulfide to endow potentiated treatment efficacy in chemo- and PARPi-resistant ovarian cancer [0.03%]
同时递送功能化镓离子和硫化氢以增强化疗和PARP抑制剂抗性卵巢癌的治疗效果
Sangsang Tang,Yangyang Li,Yifeng Fang et al.
Sangsang Tang et al.
Limited therapeutic options are available for patients with platinum-resistant ovarian cancer (OC). Herein, we developed gallium sulfide-embedded bovine serum albumin nanoformulations (Ga2S3-BSA NMs) with a size of ~ 11 nm via a self-assemb...
Retraction Note: Bone-targeting drug delivery system of biomineral-binding liposomes loaded with icariin enhances the treatment for osteoporosis [0.03%]
撤回 notice: 秦皮素生物矿化绑定脂质体骨靶向药物递送系统增强抗骨质疏松效应研究（撤稿）
Xiaoduan Sun,Jun Wei,Jiayao Lyu et al.
Xiaoduan Sun et al.
Retraction of Publication
Journal of nanobiotechnology. 2025 Feb 1;23(1):75. DOI:10.1186/s12951-025-03173-9 2025
Enhanced tumor self-targeting of lemon-derived extracellular vesicles by embedding homotypic cancer cell membranes for efficient drug delivery [0.03%]
基于同源癌细胞膜嵌合技术的柠檬来源外泌体抗肿瘤药物递送研究
Lu-Yao Yang,Guo-Wu Liang,Bing-Jie Cai et al.
Lu-Yao Yang et al.
Plant-derived nanovesicles (PDVs) as nanodrug delivery carriers have gained recognition due to their satisfactory biosafety. However, there remains a challenge to target tumor sites accurately due to the uncertain membrane protein component...
Navigating a challenging path: precision disease treatment with tailored oral nano-armor-probiotics [0.03%]
精准疾病治疗的个性化口服纳米防护益生菌方案探究
Anmei Chen,Ying Gong,Shaoquan Wu et al.
Anmei Chen et al.
Oral probiotics have significant potential for preventing and treating many diseases. Yet, their efficacy is often hindered by challenges related to survival and colonization within the gastrointestinal tract. Nanoparticles emerge as a tran...
Treatment of rheumatoid arthritis using dual-targeted and dual-response intelligent micelles: a "three birds with one stone" strategy [0.03%]
一种治疗类风湿性关节炎的“一石三鸟”策略：兼备双重靶向与智能响应的纳米药物递送体系
Rui-Bo Guo,Lu Zhang,Yang Liu et al.
Rui-Bo Guo et al.
Rheumatoid arthritis (RA) is an autoimmune disease whose pathophysiology is closely related to inflammation-associated cells and the microenvironment of inflamed joints. This study aimed to develop dual-targeted, reactive oxygen species (RO...
Lemon-derived nanoparticle-functionalized hydrogels regulate macrophage reprogramming to promote diabetic wound healing [0.03%]
基于柠檬提取物的纳米颗粒功能化水凝胶调节巨噬细胞重编程以促进糖尿病伤口愈合
Enyou Jin,Yusheng Yang,Shengjie Cong et al.
Enyou Jin et al.
The orderly regulation of immune inflammation and promotion of the regeneration of skin vessels and fibers are key to the treatment of diabetic skin injury (DSI). Although various traditional polypeptide biological dressings continue to be ...