Translational selenium nanomedicine synergizes with nab-paclitaxel to enhance antitumor effects in esophageal squamous cell cancer via selenoprotein N-mediated ER stress [0.03%]
硒纳米药物与白蛋白结合型紫杉醇协同作用通过硒蛋白N介导的内质网应激增强对食管鳞癌的抗肿瘤效应
Haoyang Huang,Shaowei Liu,Ligeng Xu et al.
Haoyang Huang et al.
Though prescribed as first-line drugs for esophageal squamous cell cancer (ESCC) therapy, the antitumor efficacy of Nab-Paclitaxel (Nab-PTX) is still unsatisfactory owing to the limitation on the dosage and therapy duration of Nab-PTX cause...
Decellularized extracellular matrix-loaded exosome hydrogel for cell-free tracheal scaffold in tracheal defect reconstruction and repair [0.03%]
负载外泌体的脱细胞基质水凝胶支气管支架用于气管缺损重建修复
Zhiming Shen,Yibo Shan,Yi Lu et al.
Zhiming Shen et al.
Tracheal reconstruction presents a significant global clinical challenge due to the unique structure and function of the trachea, which complicates its repair. Key challenges include restoring tracheal function post-transplantation, managin...
Exosome-shuttled miR-5121 from A2 astrocytes promotes BSCB repair after traumatic SCI by activating autophagy in vascular endothelial cells [0.03%]
A2星形胶质细胞源外泌体递送的miR-5121促进创伤性脊髓损伤后血脊液屏障修复中血管内皮细胞自噬激活作用机制研究
Xiaowei Wang,Zihan Zhou,Yu Zhang et al.
Xiaowei Wang et al.
Spinal cord injury (SCI) is a severe neurological disorder that significantly impacts patients' quality of life. Following SCI, the blood-spinal cord barrier (BSCB) is destroyed, leading to ischemia and hypoxia, which further exacerbates th...
Correction: Black phosphorus-Au-thiosugar nanosheets mediated photothermal induced anti-tumor effect enhancement by promoting infiltration of NK cells in hepatocellular carcinoma [0.03%]
纠正：黑磷-金-硫糖纳米片通过促进NK细胞在肝癌中的浸润增强光热诱导的抗肿瘤效应
Changchang Jia,Fan Zhang,Jiamei Lin et al.
Changchang Jia et al.
Published Erratum
Journal of nanobiotechnology. 2025 Apr 15;23(1):292. DOI:10.1186/s12951-025-03373-3 2025
Tumor microenvironment-responsive precise delivery nanocarrier potentiating synchronous radionuclide therapy and chemotherapy against cancer [0.03%]
肿瘤微环境响应的精准递送纳米载体增强放射性核素和化疗的同步癌症治疗
Jie An,Qin Zhou,Kaile Chu et al.
Jie An et al.
To achieve better therapeutic outcomes in cancer treatment, the combination of radionuclide and chemotherapy is commonly employed in clinical practice. However, the primary challenge lies in achieving precise drug delivery to tumor tissues,...
Expression of Concern: Curcumin- and resveratrol-co-loaded nanoparticles in synergistic treatment of hepatocellular carcinoma [0.03%]
表达关切：关于协同治疗肝细胞癌的姜黄素和白藜芦醇共载纳米颗粒的研究
Yongshun Zheng,Ran Jia,Jun Li et al.
Yongshun Zheng et al.
Adipose-derived small extracellular vesicle miR-146a-5p targets Fbx32 to regulate mitochondrial autophagy and delay aging in skeletal muscle [0.03%]
脂肪来源的小细胞外囊泡miR-146a-5p靶向Fbxo32调节线粒体自噬及延缓骨骼肌衰老
Mengran Qin,Yan Wang,Zihan Wang et al.
Mengran Qin et al.
This study investigates how miR-146a-5p, found in adipose tissue-derived small extracellular vesicles (sEV), influences mitochondrial autophagy and its impact on delaying skeletal muscle aging through the targeting of Fbx32. The findings hi...
Nanodiamond: a multifaceted exploration of electrospun nanofibers for antibacterial and wound healing applications [0.03%]
纳米钻石：电纺纳米纤维的多方面探索在抗菌和伤口愈合方面的应用
Hyeonseo Park,Tejal V Patil,Changyeun Mo et al.
Hyeonseo Park et al.
In this review, we explore the exciting potential of nanodiamonds (NDs) as innovative materials for future wound dressings. These materials aim to tackle important issues in wound care and offer fresh solutions. While NDs show promising mec...
Biopolymer-based bone scaffold for controlled Pt (IV) prodrug release and synergistic photothermal-chemotherapy and immunotherapy in osteosarcoma [0.03%]
基於生物聚合物的骨支架控制Pt（IV）前药释放并协同进行光热化学治疗和免疫治疗以治疗骨肉瘤
Zuyun Yan,Youwen Deng,Liping Huang et al.
Zuyun Yan et al.
Achieving bone defect repair while preventing tumor recurrence after osteosarcoma surgery has consistently posed a clinical challenge. Local treatment with 3D-printed scaffolds loaded with chemotherapeutic drugs can exert certain effects in...
Functional cobalt-doped hydrogel scaffold enhances concurrent vascularization and neurogenesis [0.03%]
功能钴掺杂水凝胶支架可同时促进血管化和神经发生
Junqing Liu,Jun Kang,Ting Zou et al.
Junqing Liu et al.
Achieving functional tissue regeneration hinges on the coordinated growth of intricate blood vessels and nerves within the defect area. However, current strategies do not offer a reliable and effective way to fulfill this critical need. To ...