Engineering Streptomyces coelicolor for heterologous expression of the thiopeptide GE2270A - a cautionary tale [0.03%]
链霉菌素科里科尔染色体工程异源表达硫霉素GE2270A的研究——一则警示故事
Francesco Del Carratore,Erik K R Hanko,Kamila Schmidt et al.
Francesco Del Carratore et al.
The thiopeptide GE2270A is a clinically relevant, ribosomally synthesised and post-translationally modified peptide (RiPP) naturally produced by Planobispora rosea. Due to the genetically intractable nature of P. rosea, heterologous express...
Beyond MRS Broth: A Soytone Medium towards affordable culturing of South African vaginal Lactobacillaceae isolates [0.03%]
超越MRS肉汤：一种用于南非乳杆菌分离培养的廉价Soytone培养基
Obakeng Luthando Jona,Marijke A Fagan-Endres,Anna-Ursula Happel et al.
Obakeng Luthando Jona et al.
This study assesses a plant-based Soytone Medium as an alternative to the animal-derived standard MRS Broth for the cultivation of Lactobacillaceae. The application focuses on five isolates that have shown probiotic potential for bacterial ...
Riccardo Iacovelli,Dominik Mojzita,Peter Richard et al.
Riccardo Iacovelli et al.
Since ancient times, humans have harnessed the vast metabolic abilities of fungi to produce food, beverages, and medicines. Biotechnology and genetic engineering have opened new avenues to tailor and enhance these abilities, transforming fu...
Genome-mining-guided discovery of coumarubrin: A novel aminocoumarin-substituted rubromycin antibiotic [0.03%]
基于基因组挖掘的氨基香豆素取代抗生素新鲁溴霉素（coumarubrin）的发现
Heiner G Weddeling,Sven T Sowa,Selina Bosshardt et al.
Heiner G Weddeling et al.
Rubromycins are bacterial aromatic polyketides containing a hallmark spiroketal pharmacophore produced by type II polyketide synthases and accessory enzymes. They generally display cytotoxic and antimicrobial properties, frequently disrupti...
Novel Supplementation of Fe3O4-Doped Green Carbonized Nanoparticles on Hydrogenases Genes and Microbial Biodiversity for Enhancing Biohydrogen Yield in Dark Fermentation Microbial Electrohydrogenesis Cells [0.03%]
Fe3O4掺杂绿色碳化纳米颗粒在暗发酵微生物电氢生成电池中增强生物制氢及对产氢基因和微生物多样性的影响研究
Hikmatullah Ahmadi,Anam Jalil,Sohail Khan et al.
Hikmatullah Ahmadi et al.
Achieving high-purity biohydrogen (Bio-H₂) production necessitates the suppression of hydrogenotrophic methanogens, as their activity can impede hydrogen yield. Various inoculum pretreatments have been employed to suppress methane-producin...
Production of extracellular L- arginase by Alcaligenes aquatilis BC2 isolated from soda lakes (Lake Chitu) of Ethiopia [0.03%]
从埃塞俄比亚苏打湖（奇图湖）中分离的产胞外L-精氨酸酶的水生阿爾克阿里根氏菌BC2
Birhan Getie Assega,Kefyalew Ayalew Getahun,Tamene Milkessa et al.
Birhan Getie Assega et al.
L-arginase is a therapeutic enzyme which hydrolyzes L-arginine to ornithine and urea. The L-arginase extracted from bacteria has an anticancer activity by causing starvation of nutrients for cancer cells. The objective of this study was to ...
Biocide-resistant Pseudomonas oleovorans isolated from water-based coatings used in construction [0.03%]
防杀菌剂的假单胞菌(Pseudomonas oleovorans)来源于建筑用水基涂料
Muatasem Latif Ali,Lionel Ferrieres,Tuulia Hyötyläinen et al.
Muatasem Latif Ali et al.
Biocides are crucial in industrial applications to minimize microbial growth and prevent product spoilage. Water-based construction coatings are susceptible to microbial contamination during manufacturing and storage and this adversely impa...
Enhancement of bioactive metabolites from solid-state fermentation of Cordyceps fungus using various substrates on ameliorating oxidative stress to liver health [0.03%]
基于不同底物固体发酵虫草菌丝体改善肝脏氧化损伤的研究
Tin Ei Cho,Guoying Zhang,Jianya Ling
Tin Ei Cho
Cordyceps, a genus of Ascomycetes, represents a group of fungi that has attracted considerable attention from both the scientific community and practitioners of traditional medicine. Extensive research has established that Cordyceps exhibit...
Recent advancement of glucosamine and N-acetyl glucosamine production using microorganisms: A review [0.03%]
微生物生产葡萄糖胺和N-乙酰葡萄糖胺的最新进展：综述
Anica Tasnim Protity,Shengde Zhou
Anica Tasnim Protity
Glucosamine (GlcN) and GlcN-based supplements, e.g. glucosamine hydrochloride, glucosamine sulfate, and N-acetyl glucosamine (GlcNAc), provide symptomatic relief to osteoarthritis patients and have been used as one of the most popular nutra...
Chunsheng Yan,Ikechukwu C Okorafor,Colin W Johnson et al.
Chunsheng Yan et al.
∆9-tetrahydrocannabinol (∆9-THC) and cannabidiol (CBD) are the most abundant natural cannabinoids isolated from the different cultivars of the Cannabis plant. Other natural ∆9-THC analogs, especially those with different alkyl chain subs...