Production of glycolic acid through whole-cell bioconversion from PET monomer ethylene glycol using engineered Corynebacterium glutamicum [0.03%]
采用工程谷氨酸棒杆菌以PET单体乙二醇为底物胞内转化合成甘醇酸
Mohammad Rifqi Ghiffary,Fong Tian Wong,Yee Hwee Lim
Mohammad Rifqi Ghiffary
In the last decade, the global warming and plastic pollution issue have driven research on developing a more sustainable platform for chemicals production from alternative feedstocks. Ethylene glycol (EG), a monomer of polyethylene terephth...
Mapping Epoxyquinoid Biosynthesis: Enzyme Functions Across Bacteria and Fungi [0.03%]
表征环氧化咯酮生物合成途径：细菌和真菌中的酶功能研究
Hsin-Yu Wei,Wei-Hsuan Lin,Hsiao-Ching Lin
Hsin-Yu Wei
Epoxyquinoids are a unique class of natural products featuring an epoxide embedded within a quinone/quinol scaffold, typically as an epoxycyclohexenone (ECH). Their striking stereochemical diversity arises from multiple permutations of epox...
Bioprospecting and Phylogenetic Analysis of Priestia flexa AW3: An Industrially Significant Amylase-Producing Bacterium from Unexplored Contaminated Soil in Layyah [0.03%]
拉亚未探索的污染土壤中具有工业价值的淀粉酶产生菌Priestia flexa AW3 的生物勘探和系统发育分析
Sobia Ramzan,Musrat Shaheen,Mohsin Khurshid et al.
Sobia Ramzan et al.
In spite of wonderful industrial applications of microbial enzymes, still most of habitats in various parts of world are unexplored for bioprospecting of industrial potent microbes. This study represents the first bioprospecting effort in L...
Sustainable β-Carotene Production from Sorghum Syrup Using Rhodotorula glutinis: Bioprocess Optimization and Scale-Up [0.03%]
利用红酵母Rhodotorula glutinis从高粱糖浆中生产可持续β-胡萝卜素：发酵工艺优化及放大研究
Kevaughn Prout,Keerthi Mandyam,Ananda Nanjundaswamy
Kevaughn Prout
β-Carotene, a key provitamin A carotenoid, is widely used as an antioxidant and natural pigment. Due to animals' inability to synthesize carotenoids, dietary sources are essential. This study utilized low-cost sorghum syrup for β-carotene...
Exploring the compatibility of phosphopantetheinyl transferases with acyl carrier proteins spanning type II polyketide synthase sequence space [0.03%]
泛酮合酶序列空间中酰基载体蛋白与磷酸潘théine转移酶的兼容性研究
Areta L N Bifendeh,Kenneth K Hsu,Christina M McBride et al.
Areta L N Bifendeh et al.
Phosphopantetheinyl transferases (PPTases) play an essential role in primary and secondary metabolism. These enzymes facilitate the post-translational activation of acyl carrier proteins (ACPs) central to the biosynthesis of fatty acids and...
Biochemical production of bio-based terephthalic acid from lignocellulosic biomass for CO2 emission reduction [0.03%]
以木质纤维素类生物质为原料生化制备生物基对苯二甲酸以减少二氧化碳排放
Seiji Nakagame,Takuma Kawao,Daiki Narita et al.
Seiji Nakagame et al.
Terephthalic acid, a key precursor for polyester production, is traditionally derived from fossil resources, contributing to global warming. Although numerous studies have explored the production of terephthalic acid from biomass polysaccha...
A Multi-Clone Kinetic Model for Characterising CHO Cell Line Variability [0.03%]
用于表征中国仓鼠卵巢细胞系多样性的多克隆动力学模型
Devi Sietaram,Pavlos Kotidis,Gary Finka et al.
Devi Sietaram et al.
This paper presents the Multi Clone Kinetic Model (MCKM), a novel generalised kinetic mechanistic model for fed-batch cultivations of diverse Chinese Hamster Ovary (CHO) cell lines, producing different recombinant monoclonal antibodies (mAb...
Characterization of S-glycosylated glycocins containing three disulfides [0.03%]
含三个二硫键的S-糖基化糖肽的特征分析
Rachel M Martini,Chandrashekhar Padhi,Wilfred A van der Donk
Rachel M Martini
Glycocins are a growing family of ribosomally synthesized and posttranslationally modified peptides (RiPPs) that are O- and/or S-glycosylated. Using a sequence similarity network of putative glycosyltransferases, the thg biosynthetic gene c...
Anti-Parkinsonian 4-hydroxy-2-pyridones from an endolichenic fungus, Tolypocladium sp. (strain CNC14) [0.03%]
来自内生真菌Tolypocladium属（菌株CNC14）的抗帕金森病4-羟基-2-吡啶酮类化合物
Jin Won Choi,Chaesun Kwon,Jin Woo Lee et al.
Jin Won Choi et al.
4-Hydroxy-2-pyridone alkaloids have attracted considerable attention because of their intriguing structures and diverse bioactivities. In our previous study, 4-hydroxy-2-pyridone alkaloids were shown to exhibit potent activity against neuro...
Screening of cellulose-degrading bacteria and its degradation and growth-promoting applications [0.03%]
纤维素降解菌的筛选及其在纤维素降解和促生长方面的应用
Mengke Chen,Xuebin Li,Er Meng et al.
Mengke Chen et al.
More than one billion tons of chaff waste are generated globally every year, but traditional recycling methods face the dual challenges of inefficiency and environmental risks, to solve this problem, this study innovatively achieves the dua...