Hybrid Modeling for Industrial Fermentation Processes with an 'Intra-Batch Experimental Design' [0.03%]
基于批内实验设计的工业发酵过程 hybrid 模型化研究
Marc Lemperle,Pedram Ramin,Julian Kager et al.
Marc Lemperle et al.
Successful development of a predictive digital twin or digital shadow enabling improved batch planning and process optimization of industrial fungal fermentation relies on the fidelity of oxygen transfer rate modeling. Such models depend, a...
Expanding the genetic toolset: Using serine recombinases to integrate riboregulatory elements into industrially relevant microbial chassis [0.03%]
拓展遗传工具箱：利用胸苷酸合成酶重组菌株在工业相关微生物底盘中整合核糖调控元件
Katherine L Wozniak,Austin L Carroll,Steffi A Davison et al.
Katherine L Wozniak et al.
To realize the full potential of biomanufacturing, the breadth of industrial microbes used to consume diverse feedstock and generate bioproducts needs to expand. As such, portable tools are required that can be used by multiple hosts for st...
Isolation and characterization of Saccharomyces cerevisiae mutants with ornithine accumulation for value-added craft beer brewing [0.03%]
酿酒酵母鸟氨酸积累突变株的分离与鉴定及其在增值精酿啤酒酿造中的应用
Akira Nishimura,Shota Isogai,Koya Yamada et al.
Akira Nishimura et al.
Ornithine is a non-proteinogenic amino acid with various health benefits, making it a promising target for functional food development. In this study, we developed the yeast Saccharomyces cerevisiae strains with elevated intracellular ornit...
Kratom Medium-Chain Dehydrogenase/Reductase Enzymes Exhibit Broad Substrate and Cofactor Promiscuity [0.03%]
kratom中链脱氢酶/还原酶酶表现出广泛的底物和辅因子特异性
Anna Koganitsky,Dong Oh Han,Vivian Liu et al.
Anna Koganitsky et al.
Medium-chain alcohol dehydrogenases/reductases (MDRs) are crucial to the biosynthesis of plant monoterpene indole alkaloids (MIAs), yet studies have focused solely on their catalytic activities with strictosidine aglycone derivatives and NA...
Bacterial contamination in starch-to-ethanol fermentations: Can bacteriocin-producing Saccharomyces cerevisiae offer a solution? [0.03%]
淀粉到乙醇发酵过程中的细菌污染：能够产杆菌肽的酿酒酵母能否提供解决方案？
Michelle Rossouw,Bianca J Campbell,Rosemary A Cripwell et al.
Michelle Rossouw et al.
Increasing interest in the bioeconomy has spurred the development of integrated methods to convert organic waste streams, particularly starch-rich substrates, into bioethanol. However, starch-based ethanol fermentations are vulnerable to ba...
Innovations in Process Engineering Approaches for Enhanced Bacteriocin Production [0.03%]
用于增强细菌素生产的工艺工程方法创新
Joan Sweetlin Shanmugam,Sreeja Shanmuga Doss
Joan Sweetlin Shanmugam
Bacteriocins are ribosomally synthesized antimicrobial peptides produced by various classes of bacteria, exhibiting broad-spectrum activity that makes them promising candidates for applications in food preservation and medicine. Their inher...
Citric acid treatment of Tetradesmus obliquus biomass reduces dry matter loss in handling, queuing, and long-term storage, while stimulating auto-fermentative production of succinic acid [0.03%]
柠檬酸处理可减少斜弯藻生物量在处理、等待和长期储存过程中的干物质损失，并能刺激丁二酸的自动发酵生成
Bradley D Wahlen,Chelsea C St Germain,Lynn M Wendt et al.
Bradley D Wahlen et al.
Post-harvest algae biomass is prone to degradation, resulting in mass loss and compositional changes, and preservation is vital to economic viability of algal products. Effective storage solutions are needed to mitigate for seasonal product...
Butyric Acid Production from Corn: Economics of Fermentative Production of a Novel Biobased Chemical [0.03%]
以玉米为原料发酵生产丁酸的经济分析
Nasib Qureshi,Somesh Mishra,Zengshe Liu et al.
Nasib Qureshi et al.
In the present study, the economic evaluation of fermentation produced butyric acid (HBu) from corn was carried out (capacity 40×103 metric tons HBu∙yr-1) and two recovery processes (distillation and adsorption) were compared. Distillatio...
Michelle Feigis,Radhakrishnan Mahadevan
Michelle Feigis
Biomanufacturing can play a pivotal role in the transition away from fossil fuel dependence for the production of chemicals and fuels. There is growing interest in inexpensive alternative bioproduction feedstocks from renewable sources that...
Bio-inspired designer cellulosomes show strongest synergy on industrial substrates under natural-like conditions [0.03%]
仿生设计的纤维素体在类似自然条件下的工业底物上表现出最强的协同效应
Babette Lamote,Julie Vanderstraeten,Nette De Ridder et al.
Babette Lamote et al.
Designer cellulosomes are engineered multi-enzyme complexes inspired by natural cellulosomes, designed to improve lignocellulose breakdown. Their modular architecture enables the spatial colocalization of diverse catalytic activities, poten...