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Kratom Medium-Chain Dehydrogenase/Reductase Enzymes Exhibit Broad Substrate and Cofactor Promiscuity

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Medium-chain alcohol dehydrogenases/reductases (MDRs) are crucial to the biosynthesis of plant monoterpene indole alkaloids (MIAs), yet studies have focused solely on their catalytic activities with strictosidine aglycone derivatives and NADPH as the redox cof... ...