Hsa-miR-10a-5p/RNF186 modulates endoplasmic reticulum stress to exacerbate the development of ulcerative colitis [0.03%]
miR-10a-5p/RNF186通过调节内质网应激促进溃疡性结肠炎的发展
Yifan Guo,Haidong Wu,Xuyong Chen et al.
Yifan Guo et al.
Ulcerative colitis (UC) is a chronic inflammatory bowel disease, and endoplasmic reticulum stress (ERS) may contribute to the pathogenesis and progression of UC. Previous research has found that hsa-miR-10a-5p is abnormally expressed in UC,...
The effect of stromal vascular fraction cells derived from epididymal and inguinal adipose tissues on in vitro spermatogenesis [0.03%]
Epididymis和inguinal脂肪组织来源的血管基质组分细胞对体外精子发生的影响
Nilgün Öksel,Merve Bulut,Selin Önen et al.
Nilgün Öksel et al.
Infertility affects 10-20% of sexually active couples and male-related factors contribute to 30-50% of all cases of infertility. The development of three-dimensional in vitro approaches to promote the differentiation of spermatogonial stem ...
Microscopic and ultrastructural insights into the nephro-therapeutic role of chitosan nanoparticles against streptozotocin-induced diabetic nephropathy [0.03%]
壳聚糖纳米颗粒对链脲佐菌素诱导的糖尿病肾病的肾保护作用的微观和超微结构见解
Aml A Elngar,Eman A Moussa,Felwa A Thagfan et al.
Aml A Elngar et al.
Diabetes mellitus is a prevalent chronic disease, with diabetic nephropathy being a significant complication that causes structural alterations in the kidneys. The purpose of this research was to examine the effects of nano-chitosan (NCh) o...
Unveiling mechanistic effects of mast cell in the progression of fibrosis and malignant transformation of oral submucous fibrosis: a systematic review and meta-analysis [0.03%]
唇黏膜硬化病纤维化进展和恶性转化中肥大细胞作用机制的系统评价和 Meta 分析
Keerthika R,Akhilesh Chandra,Dinesh Raja et al.
Keerthika R et al.
Oral submucous fibrosis (OSMF) is a ubiquitous fatal fibrotic mucosal disease with multifactorial etiology and complex pathogenesis. The role of mast cells in the pathophysiology of OSMF remains uncharted territory owing to a dearth of stud...
CTRPs, β3-AR signaling, and placental fibrin deposition: molecular and histopathological aspects of preterm birth [0.03%]
胎盘纤维蛋白沉积的分子和组织病理学特征：CTRPS、β3-AR信号与早产的关系研究
D Aşkin Özek,R Melekoğlu,N Akpolat et al.
D Aşkin Özek et al.
It has been suggested that adipokines may modulate plasma lipid levels, and β3-adrenergic receptor (β3-AR) gene expressions may affect adipokine levels and play critical roles in lipid metabolism. This study aims to determine predictive b...
Antiapoptotic effects of anthocyanin on testicular damage induced by varicocele in male rats [0.03%]
Anthocyanins对抗精索静脉曲张诱发的大鼠睾丸损伤的抗凋亡作用
Ghasem Rostami,Mohammad Reza Navabakhsh,Seyedeh Sara Salami et al.
Ghasem Rostami et al.
Varicocele is one of the most important disorders causing infertility in men, and oxidative stress is one of the most important factors affecting testicular parenchyma damage caused by varicocele. This study explored the effect of anthocyan...
Therapeutic potential of tanshinone IIA in folic acid-induced acute kidney injury: a network pharmacology approach [0.03%]
基于网络药理学丹参茋甲素IIA治疗叶酸诱导的急性肾损伤的潜力研究
Peijian Chen,Ping He,Jieting Liu et al.
Peijian Chen et al.
Acute kidney injury (AKI) is a clinical syndrome that can be caused by a variety of factors, leading to rapid decline of kidney function and increased morbidity and mortality, whilst also exerting significant economic burden on the affected...
Stereological analysis of spleen alterations in streptozotocin-nicotinamide-induced diabetic rats [0.03%]
链脲佐菌素-尼古丁胺诱导的糖尿病大鼠脾脏改变的立体学分析
Teresa Lucretia,Cherry Azaria,Imelda Imelda et al.
Teresa Lucretia et al.
Studies have indicated that spleen and white pulp atrophy develops within 5 weeks following hyperglycemia onset in streptozotocin-induced diabetic rats. This study aimed to delineate the histopathological alterations in the spleen across tw...
Effect of beta-glucan on oxidative stress, inflammation, hormonal and histopathological changes in dehydroepiandrosterone-induced polycystic ovary syndrome [0.03%]
β-葡聚糖对DHEA诱导的多囊卵巢综合征大鼠氧化应激、炎症及激素和组织学变化的影响研究
H Yüce,N Basak Turkmen,M Aydin et al.
H Yüce et al.
Beta-glucans (βTGs) are a class of dietary fibers and biologically active polysaccharides derived from natural sources, known for their diverse bioactive properties. Their documented effects include anti-tumor, anti-inflammatory, prebiotic...
Expression of programmed death-ligand 1 protein in head and neck squamous cell carcinoma and its clinicopathological correlates [0.03%]
头颈部鳞状细胞癌程序性死亡配体1蛋白表达及其临床病理相关性研究
Abdullah Ahmad Bader,Manal A Abbas,Maher A Sughayer
Abdullah Ahmad Bader
The ability to escape immune surveillance is a hallmark of malignancy. Programmed death ligand 1 (PD-L1) facilitates tumor progression by binding to the immune inhibitory receptor known as programmed cell death protein 1 (PD1) on immune cel...