Synthesis, characterization, and biological impact of PEGylated uricase from Aspergillus flavus: stability, activity, and in vitro immunological evaluation
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Despite the commercial success of protein- and peptide-based therapeutics, their clinical application remains limited due to rapid clearance and inactivation via metabolic pathways. In this study, we PEGylated Aspergillus flavus-derived uricase (Uox) using met... ...
