Locomotor and discriminative stimulus effects of NBOH hallucinogens in rodents [0.03%]
新型致幻类色氨 Narc.的运动学和辨别刺激作用研究
Daaniyal D Munir,Ritu A Shetty,Michael B Gatch et al.
Daaniyal D Munir et al.
Despite the efforts of the Drug Enforcement Administration to safeguard the public from hazardous analogs of synthetic hallucinogens, these compounds have increasingly been observed in the illicit drug market. Four novel compounds were foun...
Hesperidin produces antidepressant effects by activating AMPA receptor: enhancing synaptic proteins to promote hippocampal neuronal activities [0.03%]
柚皮素通过激活AMPA受体产生抗抑郁作用：增加突触蛋白以促进海马神经元活动
Bo Pang,Ting Cao
Bo Pang
Hesperidin treatments reduce depressive symptoms in mouse models of depression, but the mechanism that mediates its antidepressant effects is unclear. This study shows that hesperidin exerts its antidepressant effects by activating α-amino...
Alcohol consumption and preference in female rats induced by reward downshift reveals sex generality of the modulatory role of physical activity [0.03%]
奖励下降诱导的雌鼠酒精摄入与偏好：由体育活动的调节作用所揭示的性别共性
Elena Castejón,Emilio Ambrosio,Ricardo Pellón et al.
Elena Castejón et al.
Increased voluntary consumption of alcohol has been demonstrated in male rats exposed to frustrative reward downshift (the emotional self-medication effect). Access to a wheel for voluntary running abolished this effect in male rats, sugges...
Stress and glucocorticoids impair inhibitory avoidance memory retrieval and extinction in male mice: the ameliorative effect of Ginkgo biloba extract [0.03%]
应激及糖皮质激素损害雄性小鼠抑制性回避记忆的提取和消退：银杏叶提取物的改善作用
Neda Alizadeh,Fatemeh Dehbashi,Emad Gholami et al.
Neda Alizadeh et al.
Memory retrieval involves recalling previously consolidated information, while memory extinction refers to the gradual weakening of such memories after recall. Stress and glucocorticoids influence the retrieval and extinction of memory. Thi...
The administration of a phentolamine infusion into the basolateral amygdala enhances long-term memory and diminishes anxiety-like behavior in stressed rats [0.03%]
通过侧杏仁核给药酚妥拉明可增强应激大鼠长期记忆并降低焦虑样行为
Ali Dehghani,Gholam Hossein Meftahi,Hedayat Sahraei
Ali Dehghani
The basolateral amygdala (BLA) contains adrenergic receptors, which are known to be involved in stress, anxiety, and memory. The objective of this study was to explore whether inhibition of α-adrenergic receptors (by phentolamine, an α-ad...
An investigation of economic interactions between social reinforcement and heroin or cocaine in rats [0.03%]
关于社会强化与大鼠海洛因或可卡因之间经济互动的调查研究
Toni Bird,Madeline M Beasley,Emma M Pilz et al.
Toni Bird et al.
The primary goal of the present study was to determine the economic relationship between heroin and social reinforcement in rats: are they substitutes, independents, or complements? In Experiment 1, one group of rats was given a budget of r...
Evaluation of akathisia in patients receiving selective serotonin reuptake inhibitors/serotonin and noradrenaline reuptake inhibitors [0.03%]
选择性5-羟色胺再摄取抑制剂和5-羟色胺-去甲肾上腺素再摄取抑制剂治疗患者不安症状的评估研究进展
Ismail Akgoz,Huseyin Kara,Ozgen Ozcelik et al.
Ismail Akgoz et al.
Akathisia is an underestimated but disturbing extrapyramidal side effect of antidepressants, which could reduce treatment compliance in mood disorders. This study aimed to investigate the frequency and risk factors in patients treated with ...
Over-the-counter analgesic usage: associations with attentional biases in young women [0.03%]
年轻女性的非处方止痛药使用与注意偏差的相关性
Elise Solbu Roalsø,Sandra Klonteig,Brage Kraft et al.
Elise Solbu Roalsø et al.
The use of over-the-counter analgesics (OTCA) has been found to alter various aspects of emotional processing and has been linked to increased anxiety and depression symptoms. Attentional bias is an aspect of emotional processing that is cl...
Norharmane potentiated anxiolytic- and antidepressant-like responses induced by imipramine and citalopram: an isobologram analysis [0.03%]
异博果苷增强苯乙醇胺和舍曲林的抗焦虑及抗抑郁作用：等效线图分析
Fatemeh Khakpai
Fatemeh Khakpai
β-carboline compounds display a therapeutic property for treating depression and anxiety behaviors. Imipramine and citalopram play an important role in the modulation of anxiety and depression behaviors. We investigated the effects of norh...
Omeprazole affects the expression of serotonin-1A in the brain regions and alleviates anxiety in rat model of immobilization-induced stress [0.03%]
奥美拉唑影响脑区5-HT-1A表达并缓解束缚应激大鼠的焦虑行为
Sadia Basharat Ali,Raheel Saeed,Khalid Mahmood et al.
Sadia Basharat Ali et al.
Omeprazole, a drug of choice for the management of gastric hyperacidity, influences serotonergic neurotransmission in brain regions and its long-term use is known to cause stress-related behavioral deficits including anxiety. Aim of the cur...