Thrombin generation profiling in multiple myeloma: a comprehensive evaluation of prothrombotic state [0.03%]
Ciro Miele,Alessandra Vasco,Luca Manfredi et al.
Ciro Miele et al.
Objective: Venous thromboembolism is a major complication in patients with multiple myeloma (MM), with treatment strategies further increasing thrombotic risk. Conventional coagulation tests (CCT) fail to reflect the in v...
Recombinant ADAMTS13 in thrombotic thrombocytopenic purpura: a systematic review and meta-analysis [0.03%]
遗传性ADAMTS13在血栓性血小板减少性紫癜中的作用：系统评价和Meta分析
Anaya Abdul Samad,Safwat Irshad Qureshi,Akif Shahid Khan et al.
Anaya Abdul Samad et al.
Objective: Thrombotic thrombocytopenic purpura (TTP) is a rare and potentially fatal blood disorder due to deficiency of the enzyme ADAMTS13. Recombinant ADAMTS13 (rADAMTS13) is a new treatment aimed at restoring enzyme a...
To test or not to test: JAK2V617F mutation prevalence in thrombophilia profiles [0.03%]
检测还是不检测：血栓形成倾向谱中JAK2V617F突变的流行率分析
Joseph Stenberg,Elizabeth Donovan,Devon Chabot-Richards et al.
Joseph Stenberg et al.
Whole blood thrombin generation before and after eculizumab in a patient with hemolytic crisis due to paroxysmal nocturnal hemoglobinuria [0.03%]
补体抑制剂依库珠单抗治疗阵发性睡眠性血红蛋白尿症溶血危象患者的病情前后全血凝血酶生成变化
Angela Napolitano,Luca Spiezia,Cristiana Bulato et al.
Angela Napolitano et al.
Overcoming the PROSP pseudogene challenge: accurate diagnosis of a novel PROS1 variant in a patient with dural venous sinus thrombosis [0.03%]
克服PROSP假基因挑战：对一名颅内静脉窦血栓形成患者进行新型PROS1变异准确诊断
Vasant Kumar,Debadrita Ray,Manu Jamwal et al.
Vasant Kumar et al.
Hereditary protein S deficiency, a risk factor for venous thromboembolism, presents diagnostic challenges due to the PROS1 gene's homologous pseudogene, PROSP. The pseudogene's homology risks co-amplification and misinterpretation of sequen...
FIXa-triggered thrombin generation correlates with FVIII levels less than 1% in reconstituted plasma mimicking samples obtained from patients with severe hemophilia A [0.03%]
FIXa激活的凝血酶生成与重度甲型血友病患者样本中因子 VIII 水平低于1％时重组血浆模拟物中的FXIa激活呈相关性
Meijuan Huang,Jorell Gantioqui,Anthony K C Chan et al.
Meijuan Huang et al.
Introduction: More than 10% of severe hemophilia A patients are paradoxically mild bleeders despite factor VIII (FVIII) levels being
Novel compound heterozygous mutation of the KNG1 gene associated with severe HMWK deficiency in a Chinese pedigree [0.03%]
KNG1基因新杂合突变与中国一大家系严重HMWK缺乏症的关系研究
Juan Huang,Wujiao Li,Ying Wang et al.
Juan Huang et al.
Objective: This study identifies and characterizes the novel compound heterozygous mutations in the KNG1 gene responsible for severe high molecular weight kininogen (HMWK) deficiency in a 3-year-old Chinese boy. ...
Performance evaluation of Stago sthemO 301 hemostasis analyzer for routine testing, coagulation factors, and inhibitors [0.03%]
Stago sthemO 301凝血分析仪的性能评估：常规检测、凝血因子和抑制物检测
Marjorie A Goujon,Nicole Pesnel,Joffrey Feriel et al.
Marjorie A Goujon et al.
The sthemO 301 is a new hemostasis analyzer developed by Diagnostica Stago, combining simultaneously three different methodologies (i.e. clotting, chromogenic and immunological assays) on a single platform. The objective of this evaluation ...
Isolated hematuria with ureterolithiasis in an infant with late-onset vitamin K deficiency bleeding [0.03%]
维生素K缺乏晚发性出血伴尿路结石的婴儿血尿一例报告
Supapitch Chanthong,Rungrote Natesirinilkul,Chane Choed-Amphai et al.
Supapitch Chanthong et al.
Late-onset vitamin K deficiency bleeding (VKDB) usually manifests as intracranial or gastrointestinal hemorrhage, and hematuria is rarely reported. We describe a 2-month-old, exclusively breastfed male infant who had received vitamin K prop...
Impaired clot formation and hemostasis in experimental traumatic hemorrhage model [0.03%]
实验性创伤失血模型中的血凝块形成及止血异常现象
Marcus Wannberg,Iva Pruner,Apostolos Taxiarchis et al.
Marcus Wannberg et al.
Objective: Uncontrolled hemorrhage with hemostatic derangement still represents a major preventable cause of death following severe traumatic injury. The purpose of this experimental study was to further investigate the o...