Retraction: Comparing calpain- and caspase-3-mediated degradation patterns in traumatic brain injury by differential proteome analysis [0.03%]
撤回：通过差异蛋白质组分析比较创伤性脑损伤中的钙蛋白酶和半胱天冬酶-3介导的降解模式
Kevin K W Wang,Ming Cheng Liu,Veronica Akle et al.
Kevin K W Wang et al.
Woo Jun Shim,Chris Siu Yeung Chow,Shaine Chenxin Bao et al.
Woo Jun Shim et al.
Deciphering cell identity remains a central challenge in biology, as experimental profiling can only capture a fraction of the molecular diversity across human cell states. Computational modelling fills this gap by offering scalable predict...
Correction: Induced TRPC1 expression sensitizes intestinal epithelial cells to apoptosis by inhibiting NF-κB activation through Ca2+ influx [0.03%]
订正：TRPC1诱导表达通过钙离子流入抑制NF-κB活化从而促进肠上皮细胞凋亡
Jian-Ying Wang,Bernard S Marasa,Jaladanki N Rao et al.
Jian-Ying Wang et al.
Published Erratum
The Biochemical journal. 2026 Jun 3;483(6):1031-1032. DOI:10.1042/BCJ20060124_COR 2026
Correction: Post-transcriptional regulation of MEK-1 by polyamines through the RNA-binding protein HuR modulating intestinal epithelial apoptosis [0.03%]
订正：多胺通过RNA结合蛋白HuR对MEK-1的转录后调控以调节肠上皮细胞凋亡
Jian-Ying Wang,Peng-Yuan Wang,Jaladanki N Rao et al.
Jian-Ying Wang et al.
Published Erratum
The Biochemical journal. 2026 Jun 3;483(6):1033-1034. DOI:10.1042/BCJ20091459_COR 2026
Retraction: Modulation by miR-29b of intestinal epithelium homoeostasis through the repression of menin translation [0.03%]
撤稿：通过抑制menin翻译调节miR-29b介导的肠道上皮细胞稳态
Jian-Ying Wang,Miao Ouyang,Weijie Su et al.
Jian-Ying Wang et al.
Heparan sulfate promotes autoactivation of procathepsin K by destabilizing the propeptide-catalytic domain interaction [0.03%]
肝素硫酸盐通过破坏前肽与催化结构域之间的相互作用来促进活化 cathb 的自激活
Huanmeng Hao,Xiaoxiao Zhang,Jian Liu et al.
Huanmeng Hao et al.
Procathepsin K (pro-CtsK) is the zymogen of cathepsin K (CtsK), a collagenase that is essential for bone resorption. Pro-CtsK is known to bind heparan sulfate (HS), but the biological significance of the interaction remains unclear. Here, w...
Regulation between LRRK2 and PP2A signaling in cellular models of Parkinsons disease [0.03%]
帕金森病细胞模型中的LRRK2和PP2A信号通路的相互调节作用
Panagiotis S Athanasopoulos,Anna Memou,Franz Y Ho et al.
Panagiotis S Athanasopoulos et al.
Mutations in Leucine-rich repeat kinase 2 (LRRK2) are the most frequent cause of late-onset familial and idiopathic Parkinson's disease (PD), known to date. Importantly, recent data from post-mortem tissue as well as biomarker studies sugge...
Re-evaluating the rationale for targeting oxidative phosphorylation in acute myeloid leukemia [0.03%]
急性髓系白血病中靶向氧化磷酸化的再评估
Brett R Chrest,Kelsey H Fisher-Wellman
Brett R Chrest
Targeting mitochondrial oxidative phosphorylation (OxPhos) has become a recurring strategy in the treatment of cancer, particularly in acute myeloid leukemia (AML). Early reports suggested that leukemic blasts, and especially leukemia stem ...
Photocrosslinking Activity-Based Probes to Capture the Dynamics of Ubiquitin RING E3 Ligase Interactions [0.03%]
用于捕获泛素连接酶RINGS互作动力学的光交联活性基团探针
Sarah F Chandler,Michael H Tatham,Emma Branigan et al.
Sarah F Chandler et al.
Almost all cellular processes are influenced by ubiquitination. A large family of enzymes known as E3 ligases provide the specificity for ubiquitination, with the largest class among them, the RING E3s, comprising over 600 members in humans...
Deep learning insights into β-lactamase dynamics and resistance evolution [0.03%]
深入了解β-内酰胺酶动力学和耐药性进化中的深度学习
Jing Gu,Lin Gao,Shuang Chen et al.
Jing Gu et al.
The rapid global expansion of β-lactamase-mediated antimicrobial resistance demands mechanistic approaches capable of resolving the dynamics of enzyme adaptation. Although β-lactamase evolution often involves subtle rearrangements rather ...