The role of CYP3A-CYP2E1 interactions in activation of CYP3A enzymes by chronic alcohol exposure
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To examine the effect of chronic alcohol exposure on the activity of CYP3A enzymes in human liver, we studied the metabolism of CYP3A-specific substrates 7-benzyloxyquinoline (7-BQ) and ivermectin in 23 preparations of human liver microsomes (HLM) obtained fro... ...
