Jun Sun,Li Xiong,Lingfeng Yuan et al.
Jun Sun et al.
Adenosine monophosphate deaminase 1 (AMPD1) gene is highly expressed in human skeletal muscle, primarily responsible for the conversion of AMP to inosine monophosphate (IMP). It plays a crucial role in maintaining the homeostasis of the ade...
From fuzzy slippers to afferent gain: Temperature-dependent modulation of plantar mechanoreceptors [0.03%]
从暖脚拖鞋到传入增益：足底机械感受器的温度依赖性调节
Kelvin E Jones,John E Misiaszek
Kelvin E Jones
The interplay between dynamic regulation of ion-channel gating and trafficking in cardiac arrhythmogenesis [0.03%]
心脏离子通道活化与转运的动态调节在心律失常发生机制中的相互作用关系
Stefan Meier,Anna S Savchenko,Paul G A Volders et al.
Stefan Meier et al.
Cardiac arrhythmias remain a major cause of morbidity and mortality worldwide, yet therapeutic efficacy is constrained by an incomplete understanding of their multifactorial and time-dependent mechanisms. Traditional cardiac electrophysiolo...
Ava Rietdyk,Ruairí Datta
Ava Rietdyk
Vibrotactile intensity perception: Predominant influence of afferents recruited remote from stimulus site [0.03%]
振动触觉强度感知：远离刺激部位募集的传入神经元的主要影响
Kevin K W Ng,Ingvars Birznieks,Richard M Vickery
Kevin K W Ng
Sinusoidal vibratory stimuli are frequently used to study human sensory perception but have the limitation that changes in vibration frequency are accompanied by changes in the number and type of activated mechanoreceptive afferents. Here w...
Jens Bülow
Jens Bülow
The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia [0.03%]
III/IV组-afferent反馈在常氧和低氧条件下运动时呼吸、升压和代谢反应中的作用
Elliott J Jenkins,Phuong L Ha,Connor A Howe et al.
Elliott J Jenkins et al.
Group III/IV muscle afferents play a prominent role in ensuring appropriate arterial oxygenation during exercise. Exercise in hypoxia poses a major cardiorespiratory challenge due to reduced inspired oxygen pressure (PIO2). Although humans ...
APOE4 negates the effects of ovarian hormones on cerebrovascular endothelial and mitochondrial function [0.03%]
载脂蛋白E4通过影响卵泡刺激素和雌二醇对脑血管内皮细胞功能及线粒体活性的影响
Mackenzie N Kehmeier,Alexandra Famiano,Abigail E Cullen et al.
Mackenzie N Kehmeier et al.
The APOEε4 allele and oestrogen deficiency independently predispose females to an increased risk of vascular and metabolic impairments, but their cerebrovascular effects are less understood. The purpose of this study was to determine the i...
Transcutaneous auricular vagus nerve stimulation during short-term motor practice drives cortical plasticity without behavioural improvement [0.03%]
短时运动训练过程中经皮耳迷走神经刺激驱动皮质可塑性而无需行为改善
Kento Nakagawa,Rieko Osu
Kento Nakagawa
Transcutaneous auricular vagus nerve stimulation (taVNS) is emerging as a promising non-invasive neuromodulation technique to augment neurorehabilitation; however, its mechanisms in humans remain poorly understood. Animal studies indicate t...
David J Adams,Livia C Hool
David J Adams
Editorial
The Journal of physiology. 2026 Jun 19. DOI:10.1113/JP289840 2026