Panoramic voltage-sensitive optical mapping of contracting hearts using cooperative multiview motion tracking with 12 cameras [0.03%]
基于十二个视角协作运动跟踪的收缩心脏全景电压敏光学标测技术
Shrey Chowdhary,Jan Lebert,Shai Dickman et al.
Shrey Chowdhary et al.
Voltage-sensitive fluorescence imaging is widely used to image action potential waves in the heart. However, although the electrical waves trigger mechanical contraction, imaging needs to be performed with pharmacologically contraction-inhi...
Dry and humid heat acclimation induces similar adaptations and cross-acclimation benefits in trained male cyclists [0.03%]
训练有素的男车手经历干燥和潮湿热习练产生相似适应性和交叉习练益处
Peter McDonald,Kevin John,Thomas H Topham et al.
Peter McDonald et al.
This study compared adaptive responses and cross-acclimation between dry and humid heat acclimation (HA). In a cross-over design, trained males completed a heat stress test in hot-dry (Dry-HST: 42°C, 25% relative humidity [RH]) and warm-hu...
Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis [0.03%]
重组人红细胞生成素海平面促红细胞生成性作用削弱高原刺激效应反应
Roy M Salgado,Thomas A Mayer,Gabrielle E W Giersch et al.
Roy M Salgado et al.
Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis. However, it is unknown whether pharmacologically augmenting erythropoiesis with rEPO at sea level alters the e...
Gregor A Bergmann,Melissa W Tan,Katie Greenin-Whitehead et al.
Gregor A Bergmann et al.
Neural networks maintain stable activity levels by compensating for perturbations through homeostatic plasticity. However, homeostatic mechanisms operating at different levels may conflict with each other. For example, in inhibitory feedbac...
History bias and its perturbation of the stimulus representation in the macaque prefrontal cortex [0.03%]
历史偏差及其对恒河猴前额叶皮层刺激表征的干扰
Danilo Benozzo,Lorenzo Ferrucci,Francesco Ceccarelli et al.
Danilo Benozzo et al.
Multiple history biases affect our representation of magnitudes, such as time, distance and size. It is not clear whether the previous stimuli interfere with the discrimination process from the moment of stimulus presentation, during workin...
Neurons embedded in loop-like motifs act as central hubs for brain-wide integration [0.03%]
嵌于环状动机中的神经元作为全脑整合的中心节点
Fabrizio Londei,Giulia Arena,Lorenzo Ferrucci et al.
Fabrizio Londei et al.
Efficient cooperation between brain areas requires a dynamic balance between the segregation of region-specific functional roles and information broadcasting. Imaging studies of brain-wide co-ordination cannot reach the single-cell assembly...
Abcc1 deficiency protects from corticosterone but not cortisol-induced adiposity and insulin resistance in a sex-specific manner [0.03%]
ABCC1缺乏通过性别特异性方式保护皮质醇而非 Corticosterone 引起的肥胖和胰岛素抵抗
Mhairi A Paul,Boglarka Nagy,Sofia Laforest et al.
Mhairi A Paul et al.
Exogenous glucocorticoid (GC) therapy, whether physiological replacement in adrenal insufficiency or pharmacological treatment of inflammatory diseases, confers significant cardiometabolic risks, including obesity and insulin resistance. Fi...
Cardiac mitochondrial adaptations supporting high-altitude tolerance in deer mice [0.03%]
适应高海拔环境的黑尾田鼠心脏线粒体的变化规律研究
Megan Margiotta,Isabella Antonacci
Megan Margiotta