TRIP8bnano peptide prevents cAMP binding to HCN2 channels alleviating pain-like behaviors in rats with neuropathic pain
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Hyperpolarization-activated cyclic nucleotide-gated 2 (HCN2) channels regulate action potential firing in nociceptors and are critical mediators of neuronal hyperexcitability in response to inflammation and nerve injury. These channels are activated by membran... ...
