Efficacy of susceptibility-matched antibiotic treatment of non-typhoidal Salmonella bloodstream infections: a prospective observational study in hospitalized children under-five in DR Congo [0.03%]
刚果民主共和国5岁以下住院儿童非伤寒沙门氏菌败血症的药物敏感性匹配抗生素治疗的有效性:前瞻性观察研究
Bieke Tack,Daniel Vita,Jules Mbuyamba et al.
Bieke Tack et al.
Objectives: In sub-Saharan African children under-five, non-typhoidal Salmonella (NTS) frequently cause fatal bloodstream infections. Antimicrobial resistance and absence of antibiotic treatment efficacy data challenge ef...
The hidden link between cefiderocol resistance and increased virulence in Klebsiella pneumoniae: Insights from a TraDIS-based investigation [0.03%]
头孢迪洛耐药与肺炎克雷伯菌毒力增强之间的隐秘联系:基于TraDIS方法的调查研究见解
Justus U Müller,Elias Eger,Bimal Jana et al.
Justus U Müller et al.
Objective: The emergence of extensively drug-resistant Enterobacterales, particularly carbapenemase-producing Klebsiella pneumoniae, poses a serious global health threat. Cefiderocol (FDC), a sideromycin antibiotic, emplo...
Emergence of cefiderocol resistance mediated by blaAFM-1 overexpression and FptA mutations in clinical Carbapenem-Resistant Pseudomonas aeruginosa isolates [0.03%]
临床分离的碳青霉烯耐药铜绿假单胞菌中blaAFM-1过表达和FptA突变介导的头孢迪洛耐药性的产生
Yanghua Xiao,Jingwen Zhang,Feng Nie et al.
Yanghua Xiao et al.
Objectives: This study evaluated the in vitro activity of cefiderocol against clinical carbapenem-resistant Pseudomonas aeruginosa (CRPA) isolates in China prior to its clinical introduction, and investigated the mechanis...
Maheshi N Ramasamy,Zitta Barrella Harboe;ESCMID executive committee group
Maheshi N Ramasamy
CefiderocolFinder: a tool for detecting genetic adaptations implicated in cefiderocol resistance [0.03%]
CefiderocolFinder:检测舒巴坦耐药相关遗传适应的工具
Bryan van den Brand,Daan W Notermans,Nelianne J Verkaik et al.
Bryan van den Brand et al.
Objectives: Cefiderocol is a novel last-resort cephalosporin antimicrobial increasingly used for difficult-to-treat infections by multidrug-resistant microorganisms (MDRO), and is effective against carbapenem-resistant En...
Current challenges in real-world management of Clostridioides difficile infection [0.03%]
当前难辨梭菌感染管理现状中的挑战
Guido Granata,Kerrie Davies,Benoit Guery et al.
Guido Granata et al.
Carbapenemase-producing Enterobacterales in the hospital water environment: a narrative review [0.03%]
医院水环境中产碳青霉烯酶肠杆菌目:综述
Léna Sleiman,Christelle Elias,Pierre Cassier et al.
Léna Sleiman et al.
Background: Carbapenemase-producing Enterobacterales (CPE) have emerged as critical threats to global health. These bacteria are increasingly responsible for challenging outbreaks within hospital settings, leading to incr...
Performance of diagnostic procedures for bubonic plague in endemic settings in Madagascar: a prospective test accuracy sub-study within the IMASOY trial [0.03%]
马达加斯加地方性鼠疫的诊断试验准确性:IMASOY 试验中的一个前瞻性检验研究子课题
Mihaja Raberahona,Minoarisoa Rajerison,Tansy Edwards et al.
Mihaja Raberahona et al.
Objective: We aimed to assess the diagnostic value of a battery of confirmatory tests included in the World Health Organisation guidelines for bubonic plague, combined and individually, including culture, PCR and serology...
Clinical Adjudication Approach for Rapid Diagnostics Aiming to Identify Bacteria Directly from Blood [0.03%]
临床裁决方法用于快速诊断直接从血液中识别细菌的方法
Sarah B Doernberg,Lauren Komarow,Kerryl Greenwood-Quaintance et al.
Sarah B Doernberg et al.
Clinical and Microbiological Characterization of Intraoperative Findings Suggestive of Endocarditis: A retrospective cohort study [0.03%]
疑似感染性心内膜炎的术中发现的临床和微生物学特征分析:回顾性队列研究
Jean-Roch Le Henaff,Lydie Porte,Clémence Massip et al.
Jean-Roch Le Henaff et al.