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Emergence of cefiderocol resistance mediated by blaAFM-1 overexpression and FptA mutations in clinical Carbapenem-Resistant Pseudomonas aeruginosa isolates

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Objectives: This study evaluated the in vitro activity of cefiderocol against clinical carbapenem-resistant Pseudomonas aeruginosa (CRPA) isolates in China prior to its clinical introduction, and investigated the mechanisms under... ...