Changes in nasal and throat microbiota composition during and after mupirocin and chlorhexidine decolonisation treatment in asymptomatic MRSA carriers: a longitudinal observational study [0.03%]
无症状MRSA携带者使用莫匹罗星和氯己定去定植治疗期间及治疗后鼻咽微生物群组成的纵向观察研究
Sofie Marie Edslev,Cindy M Liu,Bobby Zhao Sheng Lo et al.
Sofie Marie Edslev et al.
Objectives: Decolonisation treatment of asymptomatic methicillin-resistant Staphylococcus aureus (MRSA) carriage is recommended as a preventive measure in several countries, including Denmark. This study aimed to investig...
Advanced computational analysis in metagenomic studies to support precision medicine [0.03%]
元基因组研究的先进计算分析支持精准医学
Gianmarco Piccinno,Francesco Asnicar
Gianmarco Piccinno
Background: The human microbiome has been linked to host health and is suggested to play a direct role in the onset of certain human diseases, as well as in impacting treatment efficacy. Characterizing the microbiome comp...
Benznidazole therapy is cost-saving compared to no treatment for indeterminate chronic Chagas disease in the Spanish healthcare setting [0.03%]
与无治疗相比，苯硝唑治疗在西班牙医疗保健环境中用于慢性查加斯病零期具有成本效益
Philip Erick Wikman-Jorgensen,Jara Llenas-García,Clara Crespillo-Andújar et al.
Philip Erick Wikman-Jorgensen et al.
Objectives: Chagas disease is increasingly prevalent in Europe, but the main treatment available, benznidazole, is still under-used. This study aimed to assess the cost-effectiveness of benznidazole for chronic indetermin...
Clinical utility of the DENOVA score for predicting infective endocarditis in Enterococcus faecalis bacteremia: external validation with decision curve analysis [0.03%]
DENOVA评分在预测粪肠球菌菌血症感染性心内膜炎中的临床效用：决策曲线分析的外部验证研究
Benedetta Varisco,Daniele Piovani,Elena Rosselli Del Turco et al.
Benedetta Varisco et al.
Objectives: The DENOVA score was developed to support risk stratification for infective endocarditis (IE) in patients with Enterococcus faecalis bacteremia (EfB) and to guide echocardiographic evaluation; external validat...
Dynamics of the gut and lung microbiota in severe infections: from observational studies to therapeutic strategies [0.03%]
重症感染下的肠道和肺微生物群的动态变化：从观察性研究到治疗策略
Duveke P E de Gaay Fortman,Robert F J Kullberg,W Joost Wiersinga et al.
Duveke P E de Gaay Fortman et al.
Background: Severe infections and sepsis are characterized by a disruption of intestinal and respiratory microbial communities. Loss of obligate gut anaerobes and depletion of immunomodulatory metabolites disrupt mucosal ...
Carbapenemase-producing Klebsiella pneumoniae harboring virulence-associated genes among war-affected children from the Gaza Strip [0.03%]
携带毒力相关基因的大肠鸟氨酸激酶肺炎克雷伯菌中产生碳青霉烯酶的流行情况——来自加沙地带战争受害儿童的相关数据
Andrés Pérez-López,Anju Sharma,Ruwa Mohamed et al.
Andrés Pérez-López et al.
Luo-Wei Lin,I-Shu Chen,Shao-Yu Pai et al.
Luo-Wei Lin et al.
Emerging extraintestinal Vibrio infections in Ireland from clinical and marine sources, 2020-2022 [0.03%]
2020-2022年临床和海洋来源的爱尔兰新兴肠外气单胞菌感染
Brigid Hooban,Seán Olann Whelan,Amy Burke et al.
Brigid Hooban et al.
ESCMID Clinical Guidelines on the Evaluation and Management of a Reported Antibiotic Allergy [0.03%]
ESCMID临床指南：抗菌药物过敏的评估和处理
Oana Joean,Kevin Sermet,Liat Ashkenazi-Hoffnung et al.
Oana Joean et al.
Scope: Antibiotic allergies remain one of the most frequently documented drug allergies in clinical records. It is well established that only a small proportion - estimated at 5-10% - represents true immune-mediated hyper...
Evaluating the antibacterial activity of ceftazidime/avibactam and aztreonam combinations against multidrug-resistant Stenotrophomonas maltophilia complex isolates in a hollow fiber infection model [0.03%]
头孢他啶/阿维巴坦和唑托氧胺对多药耐药的恶臭假单胞菌复合体分离株的抗菌活性评价：空纤维感染模型研究
Quentin Vallé,Rajnikant Sharma,Ngoc Minh Bui et al.
Quentin Vallé et al.
Objectives: Stenotrophomonas maltophilia is a multidrug resistant Gram-negative pathogen causing serious infections in vulnerable populations, including individuals with cystic fibrosis and immunocompromised patients. We ...