Effect of preoperative SGLT2 inhibitor use on postoperative acute kidney injury in patients with type 2 diabetes undergoing surgery: A causal inference study using routinely collected data [0.03%]
基于常规收集数据的因果推断研究:钠-葡萄糖协同转运蛋白2抑制剂对2型糖尿病患者手术后急性肾损伤的影响
Frank M Gao,Kartik Kishore,Dinesh Pandey et al.
Frank M Gao et al.
Aims: To assess whether preoperative sodium-glucose co-transporter 2 inhibitor (SGLT2i) use reduces the odds of postoperative acute kidney injury (AKI) in patients with type 2 diabetes undergoing surgery. ...
Peptidylarginine deiminase 4-mediated neutrophil extracellular trap formation aggravates β-cell damage in type 1 diabetes: A multi-model study [0.03%]
肽精氨酸异构酶4介导的中性粒细胞胞外陷阱形成加重1型糖尿病中的β细胞损伤:多模型研究
Li Lei,Yunrong Li,Shoushan Chen et al.
Li Lei et al.
Aims: Type 1 diabetes mellitus (T1DM) is an autoimmune disease characterized by progressive destruction of pancreatic β cells. Increasing evidence suggests that neutrophils and neutrophil extracellular traps (NETs) may c...
Long-term weight maintenance and risk of cardiometabolic multimorbidity and its subtypes in middle-aged and older adults: A pooled landmark analysis in China and the UK [0.03%]
中老年国人和英国人在长期维持体重状态下发生心血管元素病多重慢性疾病及其亚型的风险:中国与英国的联合数据分析研究
Yilin Pan,Jingru Bi
Yilin Pan
Aims: Cardiometabolic multimorbidity (CMM) is a growing global health challenge. Traditional body mass index (BMI) metrics, such as baseline values or simple change, fail to capture the dynamic nature of long-term weight ...
Prevalence of new-onset diabetes following COVID-19 infection: A systematic review and meta-analysis [0.03%]
新冠肺炎感染后新发糖尿病的患病率:系统回顾和荟萃分析
Jordan N Keels,Rose D LaPlante,Christopher S Lee et al.
Jordan N Keels et al.
Aim: To estimate the prevalence of new-onset diabetes in adults (≥ 18 years) following SARS-CoV-2 infection. Materials and methods: Th...
Efficacy and safety of GLP-1 receptor agonists and SGLT2 inhibitors as adjuncts to insulin in type 1 diabetes: Systematic review and meta-analysis [0.03%]
胰高糖素样肽1受体激动剂和钠葡萄糖共转运蛋白2抑制剂作为1型糖尿病患者胰岛素辅助治疗的有效性和安全性:系统评价和-meta分析
Sama M Abdel-Rahman,Rama Al-Shiab,Ermeena Shah et al.
Sama M Abdel-Rahman et al.
Aims: Adjunctive therapies to insulin for type 1 diabetes mellitus (T1DM), including glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is), may improve glycaemic cont...
Dapansutrile preserves pancreatic beta-cell function by regulating insulin vesicle membrane fusion and mitochondrial homeostasis [0.03%]
Dapansutrile通过调节胰岛素囊泡膜融合和线粒体稳态来保持胰腺β细胞功能
Ying Wu,Hongxing Fu,Min Zhu et al.
Ying Wu et al.
Aims/hypothesis: Pancreatic beta-cell dysfunction is pivotal in diabetes pathogenesis, with the NOD-like receptor protein 3 (NLRP3) inflammasome playing a crucial role. Dapansutrile (DAPA), a novel NLRP3 inhibitor, demons...
Rethinking control-IQ+ technology: Simple strategies for easy optimization [0.03%]
重新思考控制-IQ+技术:实现轻松优化的简单策略
Viral N Shah,Pratik Choudhary,Ilana Halperin et al.
Viral N Shah et al.
Control-IQ+ is an automated insulin delivery (AID) algorithm approved for people with type 1 diabetes aged 2+ years and adults aged 18+ years with type 2 diabetes. While numerous publications support improved glycaemia and quality of life f...
Effects of sotagliflozin on markers of volume status and sodium handling in patients with type 1 diabetes: A biomarker analysis of the inTandem3 clinical trial [0.03%]
索格列净对1型糖尿病患者容量状态和钠处理标志物的影响:inTandem3临床试验的生物标志物分析
Massimo Nardone,Erik Moedt,Hiddo J L Heerspink et al.
Massimo Nardone et al.
Aims: Sotagliflozin, an inhibitor of sodium-glucose co-transporter (SGLT)-1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was...
Advancing brain health prevention using explainable CKM-based predictive modelling [0.03%]
基于可解释CKM的预测模型推进脑健康预防
Jiaxuan Li,Xin Miao,Zongbao Li et al.
Jiaxuan Li et al.