Metformin Alleviates High Glucose-Induced Pyroptosis and Inflammatory Responses in HK-2 Cells via SIRT1-Associated Regulation of the TXNIP/NLRP3 Pathway
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Background: Diabetic kidney disease (DKD) is a major cause of renal failure and end-stage renal disease. Pyroptosis, a Gasdermin-dependent inflammatory form of programmed cell death, has been implicated in DKD progression. Metfor... ...
