Strategies for the steric shielding of dimetallapolyynes LyM(CC)nMLy: a personal account of approaches to insulated molecular wires and sp carbon allotropes [0.03%]
二金属聚炔LyM(CC)nMLy的位阻屏蔽策略——绝缘分子导线和sp碳同素异形体研究的个人体会
Marsel Z Shafikov,John A Gladysz
Marsel Z Shafikov
The steric shielding of reactive functionality has been extensively used throughout chemistry to enhance stabilities and facilitate studies of otherwise transient molecules. The stabilities of polyynes markedly diminish as the sp carbon cha...
Engineering the dynamic reactant-electrode interface in electroreduction systems: advances, challenges and prospects [0.03%]
电还原系统中反应物-电极界面动态调控的研究进展、挑战及展望
Kouer Zhang,Lizhen Wu,Xiaomin Xu et al.
Kouer Zhang et al.
Electrochemical reduction systems are pivotal for renewable energy conversion and sustainable chemical synthesis, yet their efficiency and selectivity are fundamentally governed by dynamic processes at the reactant-electrode interface. Movi...
Metalloprobes for gasotransmitters/biothiols linked diseases: innovation-to-implementation [0.03%]
与气体信号分子/生物硫醇相关的疾病金属探针：从创新到实施
Snehasish Debnath,Jiyoung Yoo,Yujin Kim et al.
Snehasish Debnath et al.
Early detection of diseases associated with gasotransmitters and biothiols is crucial for improving therapeutic outcomes and increasing patient survival rates. Although metal-complex-based optical probes (metalloprobes) show promise for dia...
MOFs, COFs and other porous framework materials for water purification [0.03%]
用于水净化的MOF、COF及其他多孔骨架材料
Sahel Fajal,Subhajit Dutta,Kishalay Biswas et al.
Sahel Fajal et al.
The increasing prevalence of chemically complex and persistent water contaminants necessitates the development of next-generation remediation technologies that combine selectivity, efficiency, and operational robustness. Porous framework ma...
Narangerel Ganbaatar,Xun Li,James Ormson et al.
Narangerel Ganbaatar et al.
Forces are at the heart of almost every major biological process. The widespread use of molecular machines in nature has inspired scientists to synthesize mechanically interlocked molecules (MIMs) in which controlled, relatively large ampli...
Chengsheng Yang,Doudou Hu,Xiyue Yang et al.
Chengsheng Yang et al.
Heterogeneous catalytic CO2 hydrogenation has emerged as a versatile route for converting captured CO2 and renewable H2 into fuels and chemicals, with relevance to carbon circularity, energy storage, and the progressive defossilisation of c...
Xing Zhang,Junjie Ding,Dihua Tian et al.
Xing Zhang et al.
Photo-chemoresponsive controlled drug delivery enables spatiotemporally precise interventions by transducing optical stimuli into defined drug activation events, overcoming the inability of conventional formulations to synchronize therapeut...
Multimodal antibacterial agents based on photodynamic therapy and photothermal therapy: principles, design strategies and applications [0.03%]
基于光动力疗法和光热疗法的抗菌剂：原理、设计策略及应用
Hongchen Zhai,Li Lv,Hanqi Ren et al.
Hongchen Zhai et al.
Antimicrobial resistance (AMR) and bacterial biofilms pose a dire global health threat. To combat localized infections (e.g., chronic wounds, implant-associated infections), multimodal strategies combining photodynamic therapy (PDT) and pho...
Valery Okatenko,Yuge Feng,Irina L Sinenko et al.
Valery Okatenko et al.
Humanity development has been driven by new materials since the dawn of time. Methods to mine, process, and use metals, as well as their importance for a certain age - their criticality - always evolved in parallel with civilization. With g...
The synthetic landscape of cereblon (CRBN) binders: from thalidomide to emerging chemotypes [0.03%]
从反应停到新兴药型的细胞转蛋白(CRBN)结合剂合成景观
Sergi Rafael,Carolina Sánchez-Zarzalejo,Rory Whelan et al.
Sergi Rafael et al.
Thalidomide, initially marketed as a sedative and anti-emetic, was withdrawn in the 1960s due to catastrophic teratogenic effects. Decades later, thalidomide was reconsidered as an anticancer agent, resulting in FDA approval against multipl...