Expression of hox Genes and Genes Related to Limb Development During the Homeotic Transformation of Tails Into Limbs Induced by Vitamin A in the Anuran Rana ornativentris [0.03%]
维生素A诱导蛙类尾部向 limbs发生改变过程中HOX基因及肢体发育相关基因的表达模式研究
Sho Morioka,Yoshio Yaoita,Keisuke Nakajima et al.
Sho Morioka et al.
Anuran tadpoles regenerate their tails after amputation. However, when vitamin A is administered, some anuran species such as Rana ornativentris occasionally form ectopic limbs instead of tail. Few analyses of this phenomenon at the molecul...
Fate and Specification of the Ventral Endoderm in and Outside the Foregut of the Avian Embryo at 9-12 Somite Stage [0.03%]
第9～12背节期鸡胚胎腹内胚层在原肠和前肠的命运及特征研究
Susumu Matsushita,Koko Urase
Susumu Matsushita
The fate and specification of the endoderm lining the ventral foregut and outside the foregut cranial to the anterior intestinal portal of the 9-12 somite stage avian embryo were analyzed to determine whether this endoderm was specified acc...
Roles of Extracellular Superoxide Dismutase in Regulating Cell Migration and Vesicle Trafficking in Dictyostelium and Mammalian Cells [0.03%]
胞外超氧化物歧化酶在调控Dictyostelium和哺乳动物细胞迁移及囊泡运输中的作用
Lou W Kim
Lou W Kim
Superoxide dismutases (SODs) are key regulators of reactive oxygen species (ROS) and redox balance. Although intracellular SODs have been extensively studied, growing attention has been directed toward understanding the roles of extracellul...
Integrating Tissue and Cytoplasmic Rigidity Transitions During Morphogenesis [0.03%]
发育过程中组织和细胞质刚度转变的整合
Sameer Thukral,Bipasha Dey,Yu-Chiun Wang
Sameer Thukral
Multicellular organisms generate organizational complexity through morphogenesis, in which mechanical forces orchestrate the movements and deformations of cells and tissues, while chemical signals regulate the molecular events that generate...
Super-Enhancer-Mediated DLX5 Activation Defines Regulatory Mechanisms in Human Embryonic Stem Cell-Derived Osteoblasts [0.03%]
超级增强子介导的DLX5激活定义了人胚胎干细胞来源成骨细胞中的调控机制
Shinse Fujita,Shoichiro Tani,Hiroyuki Okada et al.
Shinse Fujita et al.
Osteoblast differentiation is essential for skeletal development and homeostasis. Although bone marrow-derived mesenchymal stem/stromal cells (BM-MSCs) are commonly used to study osteoblast differentiation in the context of bone homeostasis...
Histone Demethylation Activity of UTX Contributes to the Regulation of Steroid Biosynthesis Genes in Embryonic Gonads but Is Dispensable for Gonadal Sex Determination [0.03%]
UTX组蛋白去甲基化活性调节胚胎性腺固醇生物合成基因表达但在性别决定中非必需
Mio Kojima,Mayu Fujita,Tokuko Iwamori et al.
Mio Kojima et al.
Mammalian sex is determined by the presence or absence of a Y chromosome. The sex-specific features of each cell and tissue in the body then develop in response to the sex hormones secreted by the differentiated reproductive tissues. Both t...
Cell Tracing by a Multicolor Reporter Transgenic Iberian Ribbed Newt Pleurodeles waltl [0.03%]
多色报告转基因伊比利亚肋足新薯蟾(Pleurodeles waltl)细胞追踪
Shinichi Hayashi,Ryohei Seki-Omura,Yuki Sato et al.
Shinichi Hayashi et al.
Living organisms exhibit varying regenerative abilities depending on the species. Among them, urodele amphibians have been widely used in regeneration biology due to their remarkable regenerative capacity. Iberian ribbed newts, in particula...
Foxg1 and Retinoic Acid Signaling Regulate Zonal Patterning in the Developing Olfactory Epithelium [0.03%]
FOXG1和视黄酸信号调控嗅上皮区域模式形成
Anzu Kuriyama,Carina Hanashima
Anzu Kuriyama
Odor information processing begins in the olfactory epithelium (OE), which in mice is spatially divided into two zones: the dorsomedial zone (D-zone), responsible for innate aversive behaviors, and the ventrolateral zone (V-zone), associate...
Unveiling the Molecular Pathogenesis of MCPH: Insights From Drosophila Model System [0.03%]
MCPH分子病理机制的阐释——来自果蝇模型系统的启示
Degisew Yinur Mengistu
Degisew Yinur Mengistu
Primary microcephaly (MCPH) is a rare genetic neurodevelopmental disorder caused by homologous recessive mutations of the MCPH genes. It manifests as a significant reduction in brain volume and intellectual disability at birth. More than 28...
Seiji Saito,Nobuyuki Hibino,Momoko Kyu-Shin et al.
Seiji Saito et al.
One of the most widely used methods for phenotypic analysis in developmental biology is whole-mount skeletal staining of mice. In this method, cartilage and bone are stained using two types of reagents, Alcian blue and Alizarin red, to obse...