Judith Clements
Judith Clements
Annexin A1 and resolution of inflammation: tissue repairing properties and signalling signature [0.03%]
Annexin A1与炎症消退：组织修复功能和信号特征
Thomas Gobbetti,Sadani N Cooray
Thomas Gobbetti
Inflammation is essential to protect the host from exogenous and endogenous dangers that ultimately lead to tissue injury. The consequent tissue repair is intimately associated with the fate of the inflammatory response. Restoration of tiss...
Lymphocyte signaling and activation by the CARMA1-BCL10-MALT1 signalosome [0.03%]
CARMA1-BCL10-MALT1信号小体在淋巴细胞信号转导和活化中的作用
Isabel Meininger,Daniel Krappmann
Isabel Meininger
The CARMA1-BCL10-MALT1 (CBM) signalosome triggers canonical NF-κB signaling and lymphocyte activation upon antigen-receptor stimulation. Genetic studies in mice and the analysis of human immune pathologies unveiled a critical role of the C...
Synergistic induction of cardiomyocyte differentiation from human bone marrow mesenchymal stem cells by interleukin 1β and 5-azacytidine [0.03%]
白细胞介素1β和5-氮杂胞苷协同诱导人骨髓间充质干细胞分化为心肌细胞
Safoura Khajeniazi,Mahin Solati,Yaghuob Yazdani et al.
Safoura Khajeniazi et al.
Interleukin-1β (IL-1β) is a cytokine protein expressed by cardiomyocyte in myocardial damage-associated inflammation. Although several methods are currently available for treatment of heart diseases none of them are completely successful....
IL-1 family cytokines in cancer immunity - a matter of life and death [0.03%]
细胞毒性淋巴细胞相关细胞因子在癌症免疫中的作用：一个有关生死的问题
Javier Mora,Andreas Weigert
Javier Mora
IL-1 cytokines constitute a family of biologically active proteins with pleiotropic function especially in immunity. Both protective as well as deleterious properties of individual IL-1 family cytokines in tumor biology have been described....
Dipeptidyl peptidase 9 substrates and their discovery: current progress and the application of mass spectrometry-based approaches [0.03%]
二肽基肽酶9的底物及其发现：研究进展与基于质谱的方法学应用
Claire H Wilson,Hui Emma Zhang,Mark D Gorrell et al.
Claire H Wilson et al.
The enzyme members of the dipeptidyl peptidase 4 (DPP4) gene family have the very unusual capacity to cleave the post-proline bond to release dipeptides from the N-terminus of peptide/protein substrates. DPP4 and related enzymes are current...
Membrane trafficking and proteolytic activity of γ-secretase in Alzheimer's disease [0.03%]
阿尔茨海默病中γ-分泌酶的膜转运及蛋白水解活性
Kunihiko Kanatsu,Taisuke Tomita
Kunihiko Kanatsu
γ-Secretase is an intramembrane-cleaving protease that generates various forms of amyloid-β peptides (Aβ) that accumulate in the brains of Alzheimer's disease (AD) patients. The intracellular trafficking and subcellular localization of ...
Hannu Koistinen,Erik Wallén,Henna Ylikangas et al.
Hannu Koistinen et al.
Kallikrein-related peptidase-3 (KLK3, known also as prostate-specific antigen, PSA) is highly expressed in the prostate. KLK3 possess antiangiogenic activity, which we have found to be related to its proteolytic activity. Thus, it may be po...
Emerging functions as host cell factors - an encyclopedia of annexin-pathogen interactions [0.03%]
宿主细胞因子中的新功能——Annexin-病原体相互作用百科全书
Alexander Kuehnl,Agnes Musiol,Carsten A Raabe et al.
Alexander Kuehnl et al.
Emerging infectious diseases and drug-resistant infectious agents call for the development of innovative antimicrobial strategies. With pathogenicity now considered to arise from the complex and bi-directional interplay between a microbe an...
Wei Liu,Katherine A Hajjar
Wei Liu
The formation of new blood vessels from pre-existing vasculature, the process known as angiogenesis, is highly regulated by pro- and anti-angiogenic signaling molecules including growth factors and proteases. As an endothelial cell-surface ...