The 76th Mosbacher Colloquium: AI-driven (r)evolution in structural biology and protein design [0.03%]
第76届莫斯巴赫研讨会：结构生物学与蛋白质设计的AI驱动型（革命）变迁
Birte Höcker,Ina Koch,Janosch Hennig
Birte Höcker
The 76th Mosbacher Kolloquium focused on recent advances in machine learning applications for structural biology and protein design. It covered topics spanning artificial intelligence-driven protein structure prediction, integrative modelin...
Drishan Dahal,Luis D Cruz-Zargoza,Peter Rehling
Drishan Dahal
Mitochondria are essential for cellular metabolism, serving as the primary source of adenosine triphosphate (ATP). This energy is generated by the oxidative phosphorylation (OXPHOS) system located in the inner mitochondrial membrane. Impair...
Biogenesis and function of the mitochondrial solute carrier (SLC25) family in yeast [0.03%]
酵母线粒体溶质载体(SLC25)家族的生物发生和功能
Celina Nauerz,Ophry Pines,Johannes M Herrmann
Celina Nauerz
The mitochondrial solute carrier family, also called SLC25 family, comprises a group of structurally and evolutionary related transporters that are embedded in the mitochondrial inner membrane. About 35 and 53 mitochondrial carrier proteins...
Conserved function, divergent evolution: mitochondrial outer membrane insertases across eukaryotes [0.03%]
保守的功能，分歧的进化：真核生物线粒体外膜插入酶
Anna Roza Dimogkioka,Doron Rapaport
Anna Roza Dimogkioka
Mitochondrial function relies heavily on the proper targeting and insertion of nuclear-encoded proteins into the outer mitochondrial membrane (OMM), a process mediated by specialised biogenesis factors known as insertases. These insertases ...
Rapid method for evaluation of CK2 enzymatic activity and CK2α/CK2β-interaction in Escherichia coli cell lysates [0.03%]
一种快速评估大肠杆菌裂解物中CK2酶活性和CK2α/CK2β相互作用的方法
Alexander Gast,Sebastian Schreiber,Joachim Jose
Alexander Gast
This study introduces a novel, rapid assay to measure CK2α activity in Escherichia coli cell lysates. By fusing CK2α with the fluorescent protein mScarlet it was possible to quantify CK2α concentration directly in lysates. We used the do...
Diversification of glutathione transferases in plants and their role in oxidative stress defense [0.03%]
植物谷胱甘肽转移酶的多样化及其在氧化应激防御中的作用
José M Ugalde,Manjeera Nath,Stephan Wagner et al.
José M Ugalde et al.
Plant exposure to unfavourable environmental conditions causes stress and reduces productivity. A common consequence of stress responses, are increased levels of reactive oxygen species (ROS), which if not controlled, could eventually lead ...
Johannes Buchner,Johannes M Herrmann
Johannes Buchner
Editorial
Biological chemistry. 2025 Jul 7. DOI:10.1515/hsz-2025-0168 2025
Felix Jung,David Zimmer,Timo Mühlhaus
Felix Jung
Stress responses in biological systems arise from complex, dynamic interactions among genes, proteins, and metabolites. A thorough understanding of these responses requires examining not only changes in individual molecular components but a...
Karsten Niefind,Claudia Götz,Joachim Jose
Karsten Niefind
Editorial
Biological chemistry. 2025 Jun 3. DOI:10.1515/hsz-2025-0147 2025
Triple SELEX approach for the selection of a highly specific RNA aptamer binding homoeriodictyol [0.03%]
用于选择高特异性的结合homoeriodictyol的RNA适配体的三重SELEX方法
Janis Hoetzel,Cristina Bofill-Bosch,Andres W Martinez et al.
Janis Hoetzel et al.
The application of synthetic riboswitches or aptamer-based biosensors for the monitoring of engineered metabolic pathways greatly depends on a high degree of target molecule specificity. Since metabolic pathways include close derivatives th...