Just a little prick: careful cell contacts enabled by ceramic nanostraws [0.03%]
一丝刺痛：陶瓷纳米吸管使细胞接触更轻松
Noah Brechmann,Tamara Büttner,Bernd Walkenfort et al.
Noah Brechmann et al.
Nanostraw arrays represent a novel and promising approach for the controlled delivery of substances into cells characterized by very little cellular activation or damage. Herein, we describe a sensitive strategy to establish intracellular c...
Tachykinergic signaling mediated by NK1 receptors in the respiratory parafacial region drives respiratory output and contributes to the chemoreflex response to CO2 [0.03%]
速激肽能信号通过呼吸副延髓区域的NK1受体驱动呼吸输出并参与CO2介导的化学反射反应
Octávio A C Maia,Luiz M Oliveira,Jan-Marino Ramirez et al.
Octávio A C Maia et al.
The respiratory parafacial region (pFRG) contributes critically to central chemoreception, CO2/H+ homeostasis and the regulation of all major components of the respiratory rhythm. The respiratory rhythm is also modulated by the neuropeptide...
The progression of triple-negative breast cancer is linked to a gradual decrease of the BK channel in the plasma membrane and an increase in intracellular structures [0.03%]
BK通道与三阴性乳腺癌的进展关系研究
Rodrigo Zamora-Cárdenas,Ana Laura López-Serrano,Tania Ferrer et al.
Rodrigo Zamora-Cárdenas et al.
Big Potassium (BK) channels are gated by both the membrane potential and intracellular Ca2+, and hence they have multiple physiological roles, from canonical control of cellular excitability to modulate cell metabolism, proliferation, and g...
Acid-Base homeostasis in the brain: regional heterogeneity and different Acid-Base transporters [0.03%]
大脑酸碱平衡：区域异质性和不同的酸碱转运蛋白
Masoumeh Kourosh-Arami,Alireza Komaki
Masoumeh Kourosh-Arami
The brain employs a sophisticated and multi-layered system to maintain its delicate acid-base balance, ensuring optimal conditions for neuronal and glial function. This intricate regulation involves a combination of chemical buffering, acti...
Electroacupuncture as a therapeutic intervention for obesity: mechanisms and implications [0.03%]
电针治疗肥胖的作用机制及意义研究综述
Lili Hong,Yi An,Xiaoyuan Feng et al.
Lili Hong et al.
Obesity, a prevalent metabolic disease characterized by chronic systemic inflammation and dysregulated energy homeostasis, contributes to comorbidities such as type 2 diabetes and non-alcoholic fatty liver disease. Despite advancements in l...
Activation of the alternative complement pathway and its relevance for sodium retention in experimental nephrotic syndrome [0.03%]
补体旁路途径激活及在实验性肾病综合征钠潴留中的作用
Daniel Essigke,M Zaher Kalo,Lingsi Kong et al.
Daniel Essigke et al.
The complement component C3, factor B (FB) and factor D (FD) belong to the alternative complement pathway and have been identified in urine samples from nephrotic mice. However, it is not yet known whether these factors are involved in medi...
Massimiliano Zaniboni
Massimiliano Zaniboni
Modern cardiac electrophysiology is largely focused on global electrical properties of tissue, frequently assessed by extracellular electrical recordings or optical mapping, whereas studies on the microscopic nature of action potential cond...
Modulation of cardiac contractility and redox balance via cannabinoid type II receptor activation in healthy rats [0.03%]
大麻素受体II型激活调节健康大鼠心肌收缩力和氧化还原平衡
Suzana Luisa Alves Fernandes,Yan Costa Gonçalves,Francisco Tadeu Rantin et al.
Suzana Luisa Alves Fernandes et al.
The activation of cannabinoid receptor type II (CB2r) has been demonstrated to provide cardioprotective benefits against heart diseases. Nevertheless, the physiological effects of CB2r activation in healthy myocardial tissue remain poorly u...
Impact of dietary composition on behavioural expression and gut microbiome dynamics in zebrafish [0.03%]
饮食组成对斑马鱼行为表达及肠道微生物群动态的影响
Dhanusha Sivarajan,Vidya Pothayi,Sebastian Chempakassery Devasia et al.
Dhanusha Sivarajan et al.
Diet is a key physiological factor shaping brain function and gut microbiota, which together form the dynamic gut-brain axis. This bidirectional communication system plays a pivotal role in regulating behavioural outcomes. Therefore, it is ...
Robert G Hahn
Robert G Hahn
Recent kinetic studies show that the interstitial space contains two functional fluid compartments. This study explores the prerequisites for accumulation of infused crystalloid fluid in the remote slow-exchange space ("third fluid space¨,...