Tachykinergic signaling mediated by NK1 receptors in the respiratory parafacial region drives respiratory output and contributes to the chemoreflex response to CO2
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The respiratory parafacial region (pFRG) contributes critically to central chemoreception, CO2/H+ homeostasis and the regulation of all major components of the respiratory rhythm. The respiratory rhythm is also modulated by the neuropeptide substance P which ... ...
