Roland Kocijan,Martina Behanova,Stéphane Blouin et al.
Roland Kocijan et al.
Introduction: Male idiopathic osteoporosis (MIO), defined as primary osteoporosis with unclear etiology in men, is characterized by low bone mass and increased fracture risk. The underlying pathophysiology remains poorly ...
Dietary Copper Intake and Bone Health: A Systematic Review and Meta-Analysis of Observational Studies [0.03%]
膳食铜摄入与骨骼健康：观察性研究的系统评价和meta分析
María Auxiliadora Gutiérrez-Guerra,Luis Manuel Puerto-Parejo,Elena Pastor-Ramón et al.
María Auxiliadora Gutiérrez-Guerra et al.
Studies evaluating habitual dietary copper intake and bone mineral density have garnered significant interest due to copper's indispensable role in collagen cross-linking and osteogenesis. These investigations, which employ dietary assessme...
Integrated Bioinformatics Analysis and Experimental Validation of the Role of Cellular Senescence in Osteoporosis [0.03%]
细胞衰老在骨质疏松症中作用的综合生物信息学分析和实验验证
Peiwen Wang,Xiping Hu,Chunqing Han et al.
Peiwen Wang et al.
This study assessed the effect of cellular senescence-related genes in the development of osteoporosis (OP) via the databases, which may be the potential targeted biomarkers of the OP. The development of OP is significantly influenced by ce...
Correction to: Bone Mineral Density During Treatment with The Janus Kinase Inhibitor Baricitinib in Patients with Rheumatoid Arthritis: A Monocentric Observational Study [0.03%]
托法替布治疗类风湿关节炎患者骨密度变化的队列研究及实验室指标分析：一项单中心观察性研究的更正发布公告
Nils Schulz,Thomas Asendorf,Pascal van Wijnen et al.
Nils Schulz et al.
Published Erratum
Calcified tissue international. 2025 Dec 5;116(1):148. DOI:10.1007/s00223-025-01451-0 2025
Association of ABO Blood Groups with Osteoporotic Hip Fracture Susceptibility in Chinese Adults [0.03%]
ABO血型与中国成人骨质疏松性髋部骨折易感性的关联研究
Ruyu Qi,Bin Wang,Faming Tian et al.
Ruyu Qi et al.
Does the Use of Methylphenidate Affect Bone Health? A Systematic Review and Meta-analysis of Preclinical Studies [0.03%]
甲基苯丙胺的使用会影响骨骼健康吗？一项临床前研究的系统评价和荟萃分析
Natália Couto Figueiredo,Murilo Fernando Neuppmann Feres,Irene Machowa Lubker et al.
Natália Couto Figueiredo et al.
Methylphenidate (MP) is widely prescribed for attention-deficit/hyperactivity disorder in children and adults. Concerns have emerged regarding its potential effects on bone health, including changes in bone mineral density, fracture risk, a...
Use of Analgesics in Osteogenesis Imperfecta in Denmark-A Nationwide Register-based Cohort Study [0.03%]
丹麦全国范围内的骨生成不全患者的止痛药使用情况——一项基于登记系统的队列研究
Camilla Gehling Horn,Camilla Christensen,Marc David et al.
Camilla Gehling Horn et al.
Osteogenesis imperfecta (OI) is a group of rare, hereditary diseases caused by mutations to the genes involved in the biosynthesis of collagen type 1. A cardinal feature of OI is the frequent occurrence of fractures. Individuals with OI oft...
Beyond Estrogen Deficiency: The Independent Role of FSH in Site-Specific Bone Loss in Midlife Women [0.03%]
雌激素缺乏之外：促卵泡激素在中年妇女骨丢失中的独立作用
Luis Agustín Ramírez Stieben,Lucas Ricardo Brun,Estefanía Pustilnik et al.
Luis Agustín Ramírez Stieben et al.
Follicle-stimulating hormone (FSH) was independently associated with lumbar spine (LS) bone mineral density (BMD), while estradiol (E2) predicted femoral neck BMD. A threshold effect for FSH (~ 15 mIU/mL) suggests site-specific and non-line...
Increased Osteocyte Lacunae Size and Organic Matrix Pyridinoline Content in Transiliac Bone from Patients with Axial Spondyloarthritis (axSpA) [0.03%]
强直性脊柱炎患者骨盆轴心骨组织中骨细胞空泡增大及有机基质戊二胺含量增加
Barbara M Misof,Natalia P Machado,Shibarjun Mandal et al.
Barbara M Misof et al.
Axial spondyloarthritis (axSpA) is a chronic inflammation disorder commonly associated with osteoporosis and fractures. For further information about the pathophysiology of the latter, we analyzed transiliac biopsy samples from n = 21 men w...
Efficacy and Safety of Oral Meclizine for Growth Promotion in Children with Achondroplasia: A Phase 2 Clinical Trial [0.03%]
口服美克洛嗪治疗软骨发育不全儿童促生长的疗效和安全性二期临床试验
Masaki Matsushita,Hiroshi Kitoh,Takuo Kubota et al.
Masaki Matsushita et al.
Meclizine has been shown to promote bone growth by inhibiting a key signaling pathway involved in achondroplasia (ACH). Earlier studies demonstrated its safety in children with ACH after short-term use. The purpose of this study is to asses...