Postoperative CEA is a better prognostic marker than CA19-9, hCGβ or TATI after resection of colorectal liver metastases [0.03%]
CEA术后比CA19-9、HCGβ或TATI术后更好的预测结直肠癌肝转移切除术后的预后标志物
Reetta Peltonen,Pia Österlund,Marko Lempinen et al.
Reetta Peltonen et al.
Liver metastases of colorectal cancer can be operated with a curative intent in selected cases. However, more than half of the patients have a recurrence. The aim of this study was to evaluate the prognostic and predictive value of carcinoe...
Clinical validation of nuclear factor kappa B expression in invasive breast cancer [0.03%]
侵袭性乳腺癌中核因子κB表达的临床验证
Anil Kumar Agrawal,Ewa Pielka,Artur Lipinski et al.
Anil Kumar Agrawal et al.
Breast cancer is the most commonly diagnosed cancer in Polish women. The expression of transcription nuclear factor kappa B, a key inducer of inflammatory response promoting carcinogenesis and cancer progression in breast cancer, is not wel...
MicroRNA-19 contributes to the malignant phenotypes of osteosarcoma in vitro by targeting Pax6 [0.03%]
microRNA-19通过靶向Pax6在体外促进骨肉瘤恶性表型的进展
Qingbing Meng,Ming Dai,Xuejun Nie et al.
Qingbing Meng et al.
This study was conducted to detect the expression of miR-19 and Pax6 (Paired box protein 6) in human osteosarcoma cells and the effects on biological characteristics of osteosarcoma cells. Quantitative real-time polymerase chain reaction wa...
Ibrutinib targets microRNA-21 in multiple myeloma cells by inhibiting NF-κB and STAT3 [0.03%]
依鲁替尼通过抑制NF-κB和STAT3靶向微小核糖核酸-21在多发性骨髓瘤细胞中的作用
Jing Ma,Wei Gong,Su Liu et al.
Jing Ma et al.
The oncogenic microRNA-21 contributes to the pathogenesis of multiple myeloma. Ibrutinib (also referred to as PCI-32765), an inhibitor of Bruton's tyrosine kinase, while its effects on multiple myeloma have not been well described. Here, we...
Differential expression of TGFβ isoforms in breast cancer highlights different roles during breast cancer progression [0.03%]
乳腺癌中TGFβ各亚型的差异表达揭示了其在乳腺癌发展过程中的不同作用
Mahmood Y Hachim,Ibrahim Y Hachim,Meiou Dai et al.
Mahmood Y Hachim et al.
While TGFβ plays a critical role in tumor formation and progression, the role and contribution of its three different isoforms remain unclear. In this study, we aimed at elucidating the prognostic value of the TGFβ isoforms and assessed t...
Normalizers for microRNA quantification in plasma of patients with vulvar intraepithelial neoplasia lesions and vulvar carcinoma [0.03%]
用于量化患有外阴鳞状上皮内瘤变和外阴癌患者血浆中microRNA的标准化因素
Kamil Zalewski,Marcin Misiek,Artur Kowalik et al.
Kamil Zalewski et al.
The role of circulating microRNAs as a promising tool for diagnosing cancer and monitoring anticancer therapies has been widely studied in the past decades. To date, no suitable reference microRNAs for normalizing quantitative real-time pol...
Association of mitochondrial copy number variation and T16189C polymorphism with colorectal cancer in North Indian population [0.03%]
线粒体拷贝数变异和T16189C多态性与北印度人群大肠癌的相关性研究
Bhupender Kumar,Zafar Iqbal Bhat,Savita Bansal et al.
Bhupender Kumar et al.
Globally, colorectal cancer is the third most common type of cancer. Genetic instability leading to cancer development is one of the major causes for development of cancer. Alterations in mitochondrial genome, that is, mutations, single-nuc...
Separation of cell survival, growth, migration, and mesenchymal transdifferentiation effects of fibroblast secretome on tumor cells of head and neck squamous cell carcinoma [0.03%]
头颈鳞状细胞癌成纤维细胞外泌体各组分对肿瘤细胞生存、增殖、迁移及间质转化的分离研究
Veronika Maria Metzler,Christian Pritz,Anna Riml et al.
Veronika Maria Metzler et al.
Fibroblasts play a central role in tumor invasion, recurrence, and metastasis in head and neck squamous cell carcinoma. The aim of this study was to investigate the influence of tumor cell self-produced factors and paracrine fibroblast-secr...
Anti-cancer effects of F16: A novel vascular endothelial growth factor receptor-specific inhibitor [0.03%]
F16的抗肿瘤作用：一种新型血管内皮生长因子受体特异性抑制剂
Appu Rathinavelu,Khalid Alhazzani,Sivanesan Dhandayuthapani et al.
Appu Rathinavelu et al.
Vascular endothelial growth factor receptor-2 is a dynamic target for therapeutic intervention in various types of cancers. This study was aimed to explore the anti-angiogenic activity of a novel vascular endothelial growth factor receptor-...