Kateryna Maslova,Magdalena Chechlinska,Irmina Maria Michalek et al.
Kateryna Maslova et al.
BackgroundTumour biomarkers have become increasingly important in oncology, shaping cancer diagnostics, classification, and patient management. Despite their potential, the use of cancer biomarkers in clinical settings remains limited.Objec...
An integrated bioinformatics and multi-omics investigation of the sirtuin family to identify their prognostic importance in human cancers [0.03%]
结合生物信息学和多种组学对沉默信息调节因子家族的研究以识别其在人类癌症中的预后价值
Md Shahedur Rahman,Rizone Al Hasib,Md Rezanur Rahman et al.
Md Shahedur Rahman et al.
BackgroundIn recent years, the significance of sirtuins in cancer biology has become increasingly evident, but their molecular mechanisms and prognostic impacts remain elusive.ObjectiveThe present study aimed to investigate the differential...
Osteopontin-c gene expression and subcellular localization in ovarian cancer cells: Implications for prognosis and therapeutic responses [0.03%]
卵巢癌细胞中骨桥蛋白基因表达及亚细胞定位与预后和治疗反应的关系研究
Mariana Concentino Menezes Brum,Annie Cristhine Moraes Sousa Squiavinato,Luciana da Torre Carneiro et al.
Mariana Concentino Menezes Brum et al.
BackgroundOsteopontin is a glycophosphoprotein aberrantly expressed in several tumor types, which exhibits several isoforms generated by post-translational and post-transcriptional mechanisms, including alternative splicing. Among total ost...
Asporin increases the extracellular matrix cross-links and inhibits the cancer cell migration [0.03%]
Asporin增加细胞外基质交联并抑制癌细胞迁移
Kimberly Hernandez,Caitlin H Nguyen,Girdhari Rijal
Kimberly Hernandez
BackgroundMigrating strategies of the triple-negative breast cancer (TNBC) together with its role in the establishment of tumor microenvironment (TME), supporting metastasis, have been extensively studied. Extracellular matrix (ECM) is a ma...
External validation of a serum tumor marker algorithm for early prediction of no durable benefit to immunotherapy in metastastic non-small cell lung carcinoma [0.03%]
血清肿瘤标志物算法的外部验证，用于预测无法从免疫治疗中获得持久益处的转移性非小细胞肺癌早期情况
Milou M F Schuurbiers,Freek A van Delft,Hendrik Koffijberg et al.
Milou M F Schuurbiers et al.
BackgroundImmune checkpoint inhibitors (ICIs) provide a significant survival benefit in non-small cell lung cancer (NSCLC) patients; however, accurately predicting which patients will benefit remains a challenge. As previously shown, the ST...
Cervical cancer risk in association with TNF-alpha gene polymorphisms in Bangladeshi women [0.03%]
肿瘤坏死因子基因多态性与孟加拉国妇女宫颈癌发病危险性的病例对照研究
Zasia Hossain Tishe,Sanjana Shawkat,Meherun Nessa Popy et al.
Zasia Hossain Tishe et al.
Background: Tumor necrosis factor-alpha (TNF-α) is among the vital pro-inflammatory cytokines that potentially exerts a significant influence on the immune response, hence potentially regulating the advancement of cervic...
Role of MEK1 and DIAPH3 expression in colorectal adenoma-carcinoma sequence [0.03%]
MEK1和DIAPH3表达在大肠腺瘤-癌序列中的作用分析
Abd AlRahman Mohammad Foda,Amira Kamal El-Hawary,Khaled Elnaghi et al.
Abd AlRahman Mohammad Foda et al.
Background: It is well established that most colorectal carcinomas arise from conventional adenomas through the adenoma-carcinoma sequence (ACS) model. mitogen-activated protein kinases (MAPKs) pathway has been reported a...
Erratum to: Triptolide inhibits thegrowth of osteosarcoma by regulating microRNA-181a via targeting PTEN gene in vivo and vitro [0.03%]
白英等修正：雷公藤红素通过体内和体外作用于PTEN基因调控微小核糖核酸-181а抑制成骨肉瘤生长
Chunming Jiang,Xiang Fang,Hongxu Zhang et al.
Chunming Jiang et al.