Ibrutinib targets microRNA-21 in multiple myeloma cells by inhibiting NF-κB and STAT3
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The oncogenic microRNA-21 contributes to the pathogenesis of multiple myeloma. Ibrutinib (also referred to as PCI-32765), an inhibitor of Bruton's tyrosine kinase, while its effects on multiple myeloma have not been well described. Here, we show that microRNA-... ...