The expression and prognostic value of stem cell markers Bmi-1, HESC5:3, and HES77 in human papillomavirus-positive and -negative oropharyngeal squamous cell carcinoma [0.03%]
人乳头瘤病毒阳性和阴性口咽鳞癌中干细胞标记物Bmi-1、HESC5：3和HES77的表达及其预后价值
Hesham Mohamed,Jaana Hagström,Lauri Jouhi et al.
Hesham Mohamed et al.
Human papillomavirus is detected in over 50% of oropharyngeal squamous cell carcinomas. Human papillomavirus-positive oropharyngeal squamous cell carcinomas differ from human papillomavirus-negative tumors, and both expression patterns are ...
Investigation on core-fucosylated prostate-specific antigen as a refined biomarker for differentiation of benign prostate hyperplasia and prostate cancer of different aggressiveness [0.03%]
核心岩藻糖化前列腺特异性抗原区分良性前列腺增生和不同侵袭性的前列腺癌的标志物价值研究
Robert Lang,Vinzent Rolny,Andreas Leinenbach et al.
Robert Lang et al.
Prostate cancer represents a major cause of cancer death in men worldwide. Novel non-invasive methods are still required for differentiation of non-aggressive from aggressive tumors. Recently, changes in prostate-specific antigen glycosylat...
Circulating miRNA-1290 as a potential biomarker for response to chemoradiotherapy and prognosis of patients with advanced oral squamous cell carcinoma: A single-center retrospective study [0.03%]
循环miRNA-1290作为预测晚期口腔鳞癌患者化疗联合放疗疗效和预后的潜在生物标志物：单中心回顾性研究
Hikaru Nakashima,Ryoji Yoshida,Akiyuki Hirosue et al.
Hikaru Nakashima et al.
MicroRNAs are a class of small, endogenous, noncoding 18- to 24-nucleotide-long RNAs that can regulate multiple processes related to cancer progression. However, their clinical value in patients with oral squamous cell carcinoma has not yet...
Genetic polymorphisms in CDH1 and Exo1 genes elevate the prostate cancer risk in Bangladeshi population [0.03%]
CDH1和Exo1基因的遗传多态性可提高孟加拉人群患前列腺癌的风险
Hasnain Imtiaz,Sharmin Afroz,Md Amir Hossain et al.
Hasnain Imtiaz et al.
The polymorphisms of invasion suppressor gene CDH1 and DNA mismatch repair gene Exo1 have been reported to play critical role in the development, tumorigenesis, and progression of several kinds of cancers including prostate cancer. This stu...
Gallium nanoparticles along with low-dose gamma radiation modulate TGF-β/MMP-9 expression in hepatocellular carcinogenesis in rats [0.03%]
镓纳米颗粒与低剂量γ射线调节TGF-β/MMP-9在大鼠肝细胞癌变中的表达
Fatma Sm Moawed,Sawsan M El-Sonbaty,Somaya Z Mansour
Fatma Sm Moawed
Combining chemotherapy with radiotherapy potentiates the outcome of cancer treatment for the more comprehensive attack. In the current study, we continued to assess the therapeutic efficaciousness of the newly synthesized gallium nanopartic...
Progesterone receptor expression in proliferating cancer cells of hormone-receptor-positive breast cancer [0.03%]
激素受体阳性乳腺癌增殖细胞的孕酮受体表达
Takayuki Ueno,Shigehira Saji,Tomohiro Chiba et al.
Takayuki Ueno et al.
Breast cancer has been suggested to have two distinct driving mechanisms: the hormone receptor and the growth factor receptor pathways. We hypothesized that each driving system produces a different expression pattern of estrogen-regulated g...
NADPH oxidase 4 expression in the normal endometrium and in endometrial cancer [0.03%]
过氧化物酶体增殖激活因子共刺激因子4在正常子宫内膜和子宫内膜癌中的表达
Christine Degasper,Andrea Brunner,Natalie Sampson et al.
Christine Degasper et al.
The aim of this study was to explore the role of NOX4 in the biology of the normal endometrium and endometrial cancer. NOX4 plays a key role in other adenocarcinomas and has been implicated in the pathogenesis of diabetes and obesity, which...
Role of discoidin domain receptor 2 (DDR2) and microRNA-182 in survival of women with high-grade serous ovarian cancer [0.03%]
盘状胶原受体2和微小核糖核酸-182在高级别浆液性卵巢癌患者生存中的作用
Susana Ramalho,Liliana Al De Angelo Andrade,Cássio Cardoso Filho et al.
Susana Ramalho et al.
The objective of this study is to evaluate the relationship between discoidin domain receptor 2 (DDR2) and miR-182 expression with response to platinum-based chemotherapy and survival in women with high-grade serous ovarian cancer (HGSOC). ...
Feasibility of single-cell analysis of model cancer and foetal cells in blood after isolation by cell picking [0.03%]
一种模型癌症和胎儿细胞的单细胞分析的可行性研究（细胞取用后通过血液分离）
Julie Smith,Andreas Frøslev Mathisen,Nadja Funch Richardt et al.
Julie Smith et al.
The objective of the present feasibility study was to transfer single cell line cells to either microscopy slides for downstream immune characterization or to polymerase chain reaction tubes for downstream DNA quantitation. Tumour cell line...
Metformin diminishes the unfavourable impact of Nrf2 in breast cancer patients with type 2 diabetes [0.03%]
二甲双胍可通过减少Nrf2的不良影响抑制乳腺癌患者的肿瘤生长
Elina Urpilainen,Jenni Kangaskokko,Ulla Puistola et al.
Elina Urpilainen et al.
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is a major regulator of the oxidative stress response and it is negatively regulated by Kelch-like ECH-associated protein 1 (Keap1). The Keap1-Nrf2 axis has a fundamental role in carcinogen...